Results 31 to 40 of about 235,232 (245)
IL-17 and Th17 cells in systemic sclerosis: a comprehensive review
Romanian Journal of Internal Medicine, 2017 T cells (especially T helper cells) seem to be strongly associated with systemic sclerosis pathogenesis. Th17-IL-17 axis was proved to be involved in the pathogenesis of multiple autoimmune diseases.
Bălănescu Paul +2 more
doaj +1 more source
Cell Death and Disease, 2021 The T helper 17 (Th17) cells in tumor microenvironment play an important role in colorectal cancer (CRC) progression. This study investigated the mechanism of Th17 cell differentiation in CRC with a focus on the role of tumor exosome-transmitted long ...
Junfeng Sun +6 more
semanticscholar +1 more source
Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis [PDF]
, 2010 © 2010 Cascão et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
AF Mourao +50 more
core +3 more sources
Transcriptional and posttranslational regulation of Th17/Treg balance in health and disease
European Journal of Immunology, 2021 Regulatory T (Treg) cells and T helper type 17 (Th17) cells play important roles in adaptive immune responses, antagonizing each other in immune disorders. Th17/Treg balance is critical to maintaining the immune homeostasis of human bodies and is tightly
Weiqi Zhang +6 more
semanticscholar +1 more source
Early predictors of efficacy of biological therapy for psoriasis in children
Аллергология и Иммунология в Педиатрии, 2023 .
D. G. Kuptsova +4 more
doaj +1 more source
Salt-responsive gut commensal modulates TH17 axis and disease
Nature, 2017 A Western lifestyle with high salt consumption can lead to hypertension and cardiovascular disease. High salt may additionally drive autoimmunity by inducing T helper 17 (TH17) cells, which can also contribute to hypertension.
N. Wilck +38 more
semanticscholar +1 more source
IL-6 controls susceptibility to helminth infection by impeding Th2 responsiveness and altering the Treg phenotype in vivo [PDF]
, 2013 IL-6 plays a pivotal role in favoring T-cell commitment toward a Th17 cell rather than Treg-cell phenotype, as established through in vitro model systems.
Maizels, Rick M, Smith, Katherine A
core +2 more sources
Clinical, Cosmetic and Investigational Dermatology, 2021 Guohong Hu, Xiansheng Zhou Dermatology Hospital of Jiangxi Province, Nanchang, 330001, Jiangxi, People’s Republic of ChinaCorrespondence: Guohong HuDermatology Hospital of Jiangxi Province, No.
Hu G, Zhou X
doaj
The Balance of Th17 versus Treg Cells in Autoimmunity
International Journal of Molecular Sciences, 2018 T helper type 17 (Th17) cells and pTreg cells, which share a common precursor cell (the naïve CD4 T cell), require a common tumor growth factor (TGF)-β signal for initial differentiation.
G. Lee
semanticscholar +1 more source
Cytochrome P4501-inhibiting chemicals amplify aryl hydrocarbon receptor activation and IL-22 production in T helper 17 cells [PDF]
, 2018 The aryl hydrocarbon receptor (AHR)controls interleukin 22 production by T helper 17 cells (Th17). IL-22contributes to intestinalhomeostasis but has also been implicated inchronic inflammatory disorders and colorectal cancer, highlighting the need for ...
Das, S +4 more
core +1 more source