Results 31 to 40 of about 260,137 (386)
Although mesenchymal stem cell-derived exosomes (MSC-exos) have been shown to have therapeutic effects in experimental periodontitis, their drawbacks, such as low yield and limited efficacy, have hampered their clinical application.
Yong Zhang +9 more
semanticscholar +1 more source
Histopathologic and immunological features of Imiquimod induced psoriatic mouse model
Objective: To investigate the dermatopathologic and immunological features of Imiquimod induced psoriatic mice model. Methods: Twenty BALB/c mice were grouped in IMQ-model group and control group randomly, each had 10 mice.
Zhong-zhou HUANG +5 more
doaj +1 more source
Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
doaj +1 more source
IL-17 signaling is regulated through intrinsic stability control of mRNA during inflammation
Interleukin (IL)-17 is a proinflammatory cytokine mainly produced by immune cells, especially activated T-helper 17 cells, which contribute to chronic inflammatory and autoimmune diseases including psoriasis.
Ryuta Muromoto +2 more
doaj +1 more source
Th17 cells are a distinct lineage of effector CD4+ T cells characterized by their production of interleukin (IL)-17. We demonstrate that Th17 cells also expressed IL-22, an IL-10 family member, at substantially higher amounts than T helper (Th)1 or Th2 ...
Spencer C. Liang +6 more
semanticscholar +1 more source
Metabolic regulation of regulatory T cell development and function [PDF]
It is now well established that the effector T cell (Teff) response is regulated by a series of metabolic switches. Quiescent T cells predominantly require ATP-generating processes, whereas proliferating Teff require high metabolic flux through growth ...
Alves +68 more
core +6 more sources
Th17 and Th17/Treg ratio at early HIV infection associate with protective HIV-specific CD8+ T-cell responses and disease progression [PDF]
The aim of this study was to analyze Th17 and Treg subsets and their correlation with anti-HIV T-cell responses and clinical parameters during (acute/early) primary HIV infection (PHI) and up to one year post-infection (p.i).
Cahn, Pedro +13 more
core +1 more source
Guohong Hu, Xiansheng Zhou Dermatology Hospital of Jiangxi Province, Nanchang, 330001, Jiangxi, People’s Republic of ChinaCorrespondence: Guohong HuDermatology Hospital of Jiangxi Province, No.
Hu G, Zhou X
doaj
Mycobacterium bovis (M. bovis) is a zoonotic pathogen that causes bovine and human tuberculosis. Dendritic cells play a critical role in initiating and regulating immune responses by promoting antigen-specific T-cell activation.
Han Liu +11 more
doaj +1 more source
The role of the novel Th17 cytokine IL-26 in intestinal inflammation [PDF]
Background and aims: Interleukin 26 (IL-26), a novel IL-10-like cytokine without a murine homologue, is expressed in T helper 1 (Th1) and Th17 cells. Currently, its function in human disease is completely unknown. The aim of this study was to analyse its
Auernhammer, Christoph J. +7 more
core +1 more source

