Results 21 to 30 of about 10,822,632 (330)
CXCL10+ peripheral activation niches couple preferred sites of Th1 entry with optimal APC encounter
Cell Reports, 2021 Summary: Correct positioning of T cells within infected tissues is critical for T cell activation and pathogen control. Upon tissue entry, effector T cells must efficiently locate antigen-presenting cells (APC) for peripheral activation.
Hen Prizant +12 more
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IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation
Scientific Reports, 2017 IL-10 is an immunomodulatory cytokine with a critical role in limiting inflammation in immune-mediated pathologies. The mechanisms leading to IL-10 expression by CD4+ T cells are being elucidated, with several cytokines implicated. We explored the effect
Ruth E. Mitchell +6 more
semanticscholar +1 more source
Turkish Archives of Otorhinolaryngology, 2015 Objective:With regard to the correlation between T helper1/T helper2 (Th1/Th2) cell balance and 1α,25-dihydroxyvitamin D3, active metabolite of vitamin D, we studied Th1/Th2 cell balance by measuring levels of the cytokines interleukin (IL)-4, IL-10 and ...
Erol Keleş +5 more
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Common Features of Regulatory T Cell Specialization During Th1 Responses
Frontiers in Immunology, 2018 CD4+Foxp3+ Treg cells are essential for maintaining self-tolerance and preventing excessive immune responses. In the context of Th1 immune responses, co-expression of the Th1 transcription factor T-bet with Foxp3 is essential for Treg cells to control ...
Katharina Littringer +14 more
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Transcription factors gene expression in chronic rhinosinusitis with and without nasal polyps
Radiology and Oncology, 2019 Chronic rhinosinusitis (CRS) current therapeutic approaches still fail in some patients with severe persistent symptoms and recurrences after surgery.
Soklic Tanja Kosak +6 more
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Brazilian Journal of Medical and Biological Research, 2019 The aim of this study was to evaluate the influence of artesunate on Th1 differentiation and its anti-tumor effect on ovarian cancer. A Murine ovarian cancer model was established by ID8 cells transplantation. The expression of miR-142 and Sirt1 proteins
Xiao Chen +3 more
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Frontiers in Immunology, 2022 Selective differentiation of CD4+ T helper (Th) cells into specialized subsets such as Th1 and Th2 cells is a key element of the adaptive immune system driving appropriate immune responses. Besides those canonical Th-cell lineages, hybrid phenotypes such
Philipp Burt +21 more
doaj +1 more source
PLoS ONE, 2010 BackgroundThere is consensus that experimental autoimmune encephalomyelitis (EAE) can be mediated by myelin specific T cells of Th1 as well as of Th17 phenotype, but the contribution of either subset to the pathogenic process has remained controversial ...
Helena S Domingues +4 more
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JCI Insight, 2021 Oligoarticular juvenile idiopathic arthritis (oligo JIA) is the most common form of chronic inflammatory arthritis in children, yet the cause of this disease remains unknown. To understand immune responses in oligo JIA, we immunophenotyped synovial fluid
Amélie M. Julé +24 more
doaj +1 more source
Th1/Th2 Balance in Young Subjects: Relationship with Cytokine Levels and Metabolic Profile
Journal of Inflammation Research, 2021 Ines Matia-Garcia,1 Eduardo Vadillo,2 Rosana Pelayo,3 José F Muñoz-Valle,4 Mariel García-Chagollán,4 Jaqueline Loaeza-Loaeza,1 Amalia Vences-Velázquez,1 Lorenzo Salgado-Goytia,1 Samuel García-Arellano,4 Isela Parra-Rojas1 1Facultad de Ciencias Químico ...
Matia-Garcia I +9 more
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