Results 11 to 20 of about 165,252 (249)

Spatiotemporal Cellular Networks Maintain Immune Homeostasis in the Lung

open access: yesEuropean Medical Journal Respiratory, 2020
A dynamic and intricately connected tissue-resident immune cell network continuously monitors the lungs, which are incessantly subjected to external environmental insults.
Jessica G. Borgeredo
doaj   +1 more source

Pollinosis in children and adolescents: modern aspects of pathogenesis and tendencies in therapy

open access: yesАллергология и Иммунология в Педиатрии, 2023
The development of pollinosis in children and adolescents is determined by the influence of genetic and environmental factors. The pathogenetic basis of pollinosis in children and adolescents is the differentiation of Th0 to Th2, activation of Th2cells ...
I. I. Balabolkin
doaj   +1 more source

Hypericum perforatum Alleviates Ovalbumin-Induced Asthma through Downregulating TH2 and Upregulating TH1 Related Parameters in BALB/C Mice [PDF]

open access: yesPharmaceutical Sciences
Background: Allergic asthma is a chronic and inflammatory disease of the respiratory tract, which is characterized by inflammation, airway obstruction and swelling. Anti-inflammatory compounds can be used to improve the disease severity.
Fahimeh Rostamabadi   +3 more
doaj   +1 more source

Effect of lead exposure and nutritional iron-deficiency on immune response: A vaccine challenge study in rats

open access: yesJournal of Immunotoxicology, 2020
The prevalence of iron (Fe) deficiency and subclinical lead (Pb) toxicity is high in developing countries like India, and information on their potential additive effects on immune responses is scant.
Srinivasa Reddy Yathapu   +4 more
doaj   +1 more source

Innate immune system and preeclampsia

open access: yesFrontiers in Immunology, 2014
Normal pregnancy is considered as a Th2 type immunological state that favors an immune-tolerance environment in order to prevent fetal rejection.
Alejandra ePerez-Sepulveda   +3 more
doaj   +1 more source

Th1/Th2 in aspergillosis [PDF]

open access: yesMedical Mycology, 2006
The outcome of the Th1/Th2 balance is a critical determinant of the outcome in invasive aspergillosis. The innate immune system encounters the pathogen first. Dendritic cells (DC) appear to be the critical fulcrum at the intersection of the innate immune system, and which receptors are engaged, particularly which Toll-like receptors are triggered by ...
openaire   +2 more sources

Induction of Severe Eosinophilic Esophagitis and Multi-Organ Inflammation by Airborne Allergens is Associated with IL-4/IL-13 and CCL11 but Not IgE in Genetic Susceptible Mice

open access: yesJournal of Inflammation Research, 2022
Anish Maskey,1 Kamal Srivastava,1,2 Gary Soffer,3 David Dunkin,4 Qian Yuan,5 Xiu-Min Li1,6 1Department of Pathology, Microbiology & Immunology, New York Medical College, Valhalla, NY, USA; 2General Nutraceutical Technology, LLC, Elmsford, NY, USA ...
Maskey A   +5 more
doaj  

CD4 T-cell subsets in Malaria: TH1/TH2 revisited

open access: yesFrontiers in Immunology, 2015
CD4+ T cells have been shown to play a central role in immune control of infection with Plasmodium parasites. At the erythrocytic stage of infection, IFN-γ production by CD4+ T cells and CD4+ T-cell help for the B-cell response are required for control ...
Damian ePerez-Mazliah, Jean eLanghorne
doaj   +1 more source

Th1/M1 conversion to Th2/M2 responses in models of inflammation lacking cell death stimulates maturation of monocyte precursors to fibroblasts

open access: yesFrontiers in Immunology, 2013
We have demonstrated that cardiac fibrosis arises from the differentiation of monocyte-derived fibroblasts. We present here evidence that this process requires sequential Th1 and Th2 induction promoting analogous M1 (classically activated) and M2 ...
JoAnn eTrial   +5 more
doaj   +1 more source

Beyond CCR7: dendritic cell migration in type 2 inflammation

open access: yesFrontiers in Immunology
Conventional dendritic cells (cDCs) are crucial antigen-presenting cells that initiate and regulate T cell responses, thereby shaping immunity against pathogens, innocuous antigens, tumors, and self-antigens. The migration of cDCs from peripheral tissues
Audrey Meloun   +2 more
doaj   +1 more source

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