Results 21 to 30 of about 401,370 (283)
Modulating Th2 Cell Immunity for the Treatment of Asthma
Frontiers in Immunology, 2021 It is estimated that more than 339 million people worldwide suffer from asthma. The leading cause of asthma development is the breakdown of immune tolerance to inhaled allergens, prompting the immune system's aberrant activation.
B. León, A. Ballesteros-Tato
semanticscholar +1 more source
Recent advances in understanding the Th1/Th2 effector choice
Faculty Reviews, 2021 For over 35 years since Mosmann and Coffman proposed the seminal “type 1 T helper (Th1)/type 2 T helper (Th2)” hypothesis in 1986, the immunological community has appreciated that naïve CD4 T cells need to make important decisions upon their activation ...
M. Butcher, Jinfang Zhu
semanticscholar +1 more source
Th1/Th2 Imbalance and Elevated PD-L1 in Pleural Effusion Predict the Risk of Multi-Drug Resistant Tuberculous Pleuritis [PDF]
Iranian Journal of Immunology, 2020 Background: Patient immune status might be indicative of the variance in bacterial genetics in drug-resistant tuberculous pleuritis and could be used for predicting the risk of multi-drug resistant tuberculous pleuritis (MDR-TB).
Hongyan Xu +3 more
doaj +1 more source
In Vivo CD4+ T Cell Differentiation and Function: Revisiting the Th1/Th2 Paradigm.
Annual Review of Immunology, 2020 The discovery of CD4+ T cell subset-defining master transcription factors and framing of the Th1/Th2 paradigm ignited the CD4+ T cell field.
Mikel Ruterbusch +3 more
semanticscholar +1 more source
Frontiers in Immunology, 2020 During pregnancy, various immune effectors and molecules participating in the immune-microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus.
Wen-juan Wang +3 more
semanticscholar +1 more source
Review – Helicobacter: inflammation, immunity and vaccines [PDF]
Microbiota in Health and Disease, 2021 Helicobacter pylori is a bacterium that colonizes the human stomach and is the risk factor for severe gastroduodenal diseases, such as gastric cancer, gastric lymphoma, autoimmune gastritis and peptic ulcer. H.
M. D’Elios, M. de Bernard
doaj +1 more source
Helminthiasis, eosinophils, COVID-19 and vaccination
Southern African Journal of Infectious Diseases, 2022 No abstract available.
Miles B. Markus
doaj +1 more source
CD11a polymorphisms regulate TH2 cell homing and TH2-related disease [PDF]
Journal of Allergy and Clinical Immunology, 2014 TH2-dependent diseases vary in severity according to genotype, but relevant gene polymorphisms remain largely unknown. The integrin CD11a is a critical determinant of allergic responses, and allelic variants of this gene might influence allergic phenotypes.We sought to determine major CD11a allelic variants in mice and human subjects and their ...
Knight, John +6 more
openaire +3 more sources
Inhibitory control of feature selectivity in an object motion sensitive circuit of the retina [PDF]
, 2017 Object motion sensitive (OMS) W3-retinal ganglion cells (W3-RGCs) in mice respond to local movements in a visual scene but remain silent during self-generated global image motion. The excitatory inputs that drive responses of W3-RGCs to local motion were
Kerschensteiner, Daniel, Kim, Tahnbee
core +3 more sources
Paracrine IL-2 Is Required for Optimal Type 2 Effector Cytokine Production [PDF]
, 2017 IL-2 is a pleiotropic cytokine that promotes the differentiation of Th cell subsets, including Th1, Th2, and Th9 cells, but it impairs the development of Th17 and T follicular helper cells.
Cherukur, Yesesri +8 more
core +1 more source