Results 61 to 70 of about 22,410 (257)

Robust Systemic and Mucosal Immune Responses to Coxsackievirus B3 Elicited by Spider Silk Protein Based Nanovaccines via Subcutaneous Immunization

open access: yesAdvanced Functional Materials, Volume 35, Issue 15, April 10, 2025.
Spider minor ampullate silk protein (MiSp) and retinoic acid (RA) based nanovaccine are capable of eliciting both mucosal and systemic immune responses following subcutaneous administration and demonstrate significant protective effects against CVB3 infection in mice.
Xingmei Qi   +4 more
wiley   +1 more source

The Five Elements of Th1-Th2 System [PDF]

open access: yesarXiv, 2008
The T helper (Th) phenotypes, Th1/Th2, are acquired upon interaction of a naive T helper cell and an antigen presenting cell (APC). Naive T helper cells may differentiate into either phenotype, and the actual outcome is determined by the density and avidity of the antigenic determinants presented by the APC, and the APCs inherent costimulatory ...
arxiv  

Enhanced Terahertz Spectroscopy of a Monolayer Transition Metal Dichalcogenide

open access: yesAdvanced Functional Materials, EarlyView.
An ad‐hoc engineered metallic surface is employed to perform enhanced terahertz spectroscopy of a monolayer transition metal dichalcogenide (TMD). Thanks to a local absorption boost of 104, this technique allows for the extraction of the phonon resonance features and effective permittivity of the 2D material, paving the way for the rational design of ...
Xin Jin   +11 more
wiley   +1 more source

Dissecting the enigma of scleroderma: possible involvement of the kynurenine pathway

open access: yesPteridines, 2017
The kynurenine pathway (KP) is the metabolic pathway via which L-tryptophan is converted to nicotinamide. It serves important immune-regulatory roles. This article will review the evidence for involvement of the KP in scleroderma and present a possible ...
Noakes Rowland
doaj   +1 more source

Modeling the influence of TH1 and TH2 type cells in autoimmune diseases [PDF]

open access: yesarXiv, 2000
A sharp TH1/TH2 dichotomy has often been used to define the effects of cytokines on autoimmune diseases. However contradictory results in recent research indicate that the situation may be more complex. We build here a simple mathematical model aimed at settling the contradictions.
arxiv  

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Role of eosinophils in protective immunity against secondary nematode infections

open access: yesImmunological Medicine, 2019
Infections with parasites, especially those involving nematodes that invade tissues, induce a strong Th2-type immune response, which increases immunoglobulin E and eosinophil levels in the blood and tissues.
Koubun Yasuda, Etsushi Kuroda
doaj   +1 more source

Omnidirectional Transmissive Acoustic Metasurfaces Based on Goldberg Polyhedra

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces omnidirectional acoustic metasurfaces capable of manipulating wavefronts in multiple arbitrary directions simultaneously. A full‐stack pipeline for design, optimization, and fabrication is presented to construct near‐spherical holograms based on Goldberg polyhedra.
Andrea Achilleos   +3 more
wiley   +1 more source

Recent Developments in Immune Network Theory including a concept for an HIV Vaccine [PDF]

open access: yesarXiv, 2008
The symmetrical network theory is a framework for understanding the immune system, that dates back to the mid 1970s. The symmetrical network theory is based on symmetrical stimulatory, inhibitory and killing interactions between clones that are specific for each other.
arxiv  

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 10, April 15, 2025.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden   +5 more
wiley   +1 more source

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