England's Dementia Diagnosis Landscape: Strengths, Limitations, and Future Directions
International Journal of Geriatric Psychiatry, Volume 41, Issue 7, July 2026.ABSTRACT Background The National Health Service (NHS) England Primary Care Dementia Data (PCDD) provides a comprehensive dementia registry, underpinning national policy to improve diagnosis, care, and support. Methods This paper evaluates the PCDD in comparison with international quality dementia registries (SveDem, NorCog, ADNeT). Results We highlight
Jemma Hazan +2 more
wiley +1 more source
Crashing by design: Utilizing DNA damage for MCC differentiation. [PDF]
Trends Cell BiolSuva EE, Mitchell BJ.
europepmc +1 more source
Hematological Oncology, Volume 44, Issue 4, July 2026.ABSTRACT Chronic lymphocytic leukemia (CLL) is a clinically and molecularly heterogeneous disease. PKMYT1, a G2/M cell cycle kinase, has been implicated in tumor progression in several cancers, but its role in CLL remains unclear. We evaluated PKMYT1 expression in primary CLL samples and analyzed associations with cytogenetic features and clinical ...
Elizabete Cristina Iseke Bispo +6 more
wiley +1 more source
Association between dynamic digital radiography findings and post-extubation respiratory deterioration: A retrospective exploratory analysis of a prospectively collected ICU cohort. [PDF]
PLoS OneKomatsu S +4 more
europepmc +1 more source
RNA Modifications in Tumor Microenvironment: A New Dimension for Cancer Treatment
MedComm, Volume 7, Issue 7, July 2026.Tumor initiation and progression depend on a supportive and highly heterogeneous tumor microenvironment (TME). RNA modifications regulate signaling pathways and cytokine networks that shape TME dynamics, facilitating interactions between cancer cells and noncancerous stromal cells, and ultimately promoting immune evasion and tumor progression ...
Qiwen Li +3 more
wiley +1 more source
Molecular insights into DNA damage response plasticity in glioma stem cells. [PDF]
Commun BiolMolinari NC +6 more
europepmc +1 more source
Cellular Senescence and Aging: Mechanisms, Disease Convergence, and Therapeutic Frontiers
MedComm, Volume 7, Issue 7, July 2026.This schematic illustrates the hierarchical and interconnected nature of the primary molecular hallmarks of aging. The progression of aging is driven by a convergence of intrinsic molecular insults. Within the nucleus, genomic instability and telomere attrition trigger persistent DDR, accompanied by extensive epigenetic alterations.
Guowei Cai +10 more
wiley +1 more source
From discarding to leveraging: quality-aware collaborative learning for robust diabetic retinopathy grading. [PDF]
Front Med (Lausanne)Pan Y +5 more
europepmc +1 more source
Molecular Interplay of PARN and Telomerase: Tail Modifiers and Disease Implications
WIREs RNA, Volume 17, Issue 4, July/August 2026.Schematic representation of the molecular interplay between PARN, telomerase‐associated, and the involvement of p53 in regulating telomere maintenance and genome stability. The top panel shows how normal PARN levels are involved in regulating p53 levels and balanced telomerase activity through their regulatory interaction with TERC and TERRA, thus ...
Sujitha Felicitus +5 more
wiley +1 more source
CDK7 as a Potential Exploratory Biomarker for Distinguishing Acute Myocardial Infarction Subtypes via DDR Pathways: Evidence From a Bangladeshi Cohort. [PDF]
Clin CardiolRipon RH +6 more
europepmc +1 more source