Results 101 to 110 of about 133,879,868 (285)

[The Warburg effect: from theory to therapeutic applications in cancer].

, 2013
International audienceCancer cell metabolism described by Otto Warburg in the thirties became a cancer specific hallmark, also called "Warburg effect".
Razungles, Julie, Cavaillès, Vincent, Stéphan Jalaguier, Julie Razungles, Jalaguier, Stéphan, Catherine Teyssier, Teyssier, Catherine, Vincent Cavaillès   +7 more
core   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Warburg non finito

, 2006
Introduzione agli appunti di viaggio di Aby Warburg in New ...
GHELARDI, Maurizio
core  

Weakly Coordinated Solvent Network‐Induced Ternary Water‐Deficient Eutectic Electrolytes for Low‐Polarization Zn Anodes

Advanced Science, EarlyView.
A water‐deficient ternary eutectic electrolyte employs weakly coordinating solvents to decouple strong solvation interactions, constructing a loose and dynamic solvation network. This optimized solvation structure accelerates Zn2+ transport and interfacial kinetics, promotes robust SEI formation, and ultimately enables highly stable and reversible Zn ...
Quancai Li, Jing Liang, Jiayu Wang, Qian Wang, Hehe Ren, Ziyi Gong, Vellaisamy A. L. Roy, Wei Wu   +7 more
wiley   +1 more source

The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells

BMC Cancer, 2018
Background Cancer cachexia is a cancer-induced metabolic disorder and a major cause of cancer-induced death. The constituents of cancer cachexia include an increase in energy expenditure, hepatic gluconeogenesis, fat lipolysis, and skeletal-muscle ...
Feng Wang, Hongyi Liu, Lijuan Hu, Yunfei Liu, Yijie Duan, Rui Cui, Wencong Tian   +6 more
doaj   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

Advanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran, Yanchun Fang, Shengming Ruan, Juling Wang, Songbai Liu, Yuan Mao, Dongsheng Hou, Yanping Wang, Zi Ye, Qiong Li, Daoxiang Zhang   +10 more
wiley   +1 more source

Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors.

PLoS Computational Biology, 2018
Cancer metabolism has received renewed interest as a potential target for cancer therapy. In this study, we use a multi-scale modeling approach to interrogate the implications of three metabolic scenarios of potential clinical relevance: the Warburg ...
Mengrou Shan, David Dai, Arunodai Vudem, Jeffrey D Varner, Abraham D Stroock   +4 more
doaj   +1 more source

Nachforschungen zum Schicksal der Jüdischen Kultusgemeinde zu Warburg.

, 1977
Letter soliciting information about the Jewish community in Warburg in North Rhine-Westphalia, Germany. It includes a list (names and addresses) of former members of this community worldwide. Also included is a booklet with photographs of
Hermes, Hermann
core  

Glycolysis inhibition for anticancer treatment The Warburg effect [PDF]

, 2014
PósterReview the peculiarities in the energy metabolism of cancer cells (Warburg effect). Review of the different inhibitors of this pathway, and combinations with other therapeutic methods of cancer ...
Hernández Ubieto, Clara, Universitat Autònoma de Barcelona. Facultat de Veterinària   +1 more
core   +1 more source