Results 101 to 110 of about 53,058 (296)

Image_2_Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α.tif

, 2019
The Warburg effect is a peculiar feature of cancer’s metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal tissue.
Yurou Xie (8054852), Yifan Yang (170387), Jinglong Pang (8054858), Yesen Li (4430377), Tianhui Hu (166418), Kaifeng Zheng (8054855), Daxuan Wang (8054864), Yan-yan Zhan (5985440), Xiaoting Hong (2316733), Hanwei Cao (166403), Panying Mi (8054861), Xiaolin Xu (493031), Wenqing Zhang (56658), Linhai Zhong (8054849), Gang Song (34196)   +14 more
core   +1 more source

Low Resistance Interphase Formation at the PEO‐LiTFSI|LGPS Interface in Lithium Solid‐State Batteries

Advanced Materials Interfaces, EarlyView.
Interfacial charge transfer and low‐resistance interphase formation between PEO‐based polymer and Li10GeP2S12 solid electrolytes are investigated using multi‐electrode impedance spectroscopy and advanced analytical techniques such as XPS and ToF‐SIMS.
Ujjawal Sigar, Timo Weintraut, Sebastian L. Benz, Semih Engün, Sascha Kremer, Anja Henss, Felix H. Richter   +6 more
wiley   +1 more source

Warburg Effect: a Diagnostic Challenge for Clinicians

, 2019
International audienceThe Warburg effect is a common and serious complication at the onset or during the management of solid neoplasms or haematological malignancies.
Maize, J., Marolleau, J-P, Gruson, B., Marc, J., Brault, C., Delette, C., Zerbib, Y.   +6 more
core   +1 more source

BioEISense: A Microfluidic Platform for Real‐Time Monitoring of Staphylococcus aureus Biofilm Formation and the Efficacy of Antibiofilm Agents

Advanced Materials Interfaces, EarlyView.
BioEISense is a microfluidic device with integrated impedance sensors, for real‐time, label‐free monitoring of S. aureus biofilms. In this study, the biofilm culture conditions were optimized to support sensitive and reproducible detection of biofilm formation and eradication under dynamic flow‐through conditions. The system was also validated for both
Jéssica Amorim, Laura Vesalainen, Loïc Dreano, Markus Haapala, Cristina D. Cruz, Päivi Tammela, Tiina M. Sikanen   +6 more
wiley   +1 more source

Interaction networks of macrophage glycolysis and inflammation in sepsis: mechanisms and therapeutic potential

Frontiers in Immunology
Sepsis is a severe threat to human health with high mortality rates, but so far its pathogenesis is unclear and lacks effective therapeutic drugs. Macrophages function as one of the most important innate immune cells and play an integral role in the ...
Peiyao Luo, Hao Liu, Hao Liu, Ting Zhang, Ting Zhang, Wenfang He   +5 more
doaj   +1 more source

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension

Nature Communications, 2019
Pulmonary hypertension is characterized by a metabolic switch similar to the Warburg effect in cancer. Here Dabral et al. describe a RASSF1a-HIF-1α feedforward loop driving the Warburg effect both in a mouse model of hypoxia-induced pulmonary ...
Swati Dabral, Christian Muecke, Chanil Valasarajan, Mario Schmoranzer, Astrid Wietelmann, Gregg L. Semenza, Michael Meister, Thomas Muley, Tamina Seeger-Nukpezah, Christos Samakovlis, Norbert Weissmann, Friedrich Grimminger, Werner Seeger, Rajkumar Savai, Soni S. Pullamsetti   +14 more
doaj   +1 more source

An Attempt to Reverse Aspects of the Warburg Effect Using 17 β-estradiol

, 2012
A Thesis submitted to The University of Arizona College of Medicine - Phoenix in partial fulfillment of the requirements for the Degree of Doctor of Medicine.The Warburg effect is defined as the propensity for cancer cells to favor glycolysis over ...
Nelson, Vanessa
core  

Upcycling Compact Discs Into Ultra‐Stable, Flexible, and Stretchable Nanoporous Gold Electrodes for Enhanced Biosensing Performance

Advanced Materials Technologies, EarlyView.
This article highlights the development of robust and high‐performance flexible and stretchable biosensors that maintain long‐term functionality and optimal electrical conductivity under mechanical deformation, utilizing sustainable and cost‐effective manufacturing principles.
Mousa H. Aldosari, Ahyeon Koh
wiley   +1 more source

Warburg Effect in Oncology

International Journal of Trends in OncoScience
The Warburg effect, defined by cancer cells’ preference for aerobic glycolysis over mitochondrial oxidative phosphorylation for energy production, has been a central topic in cancer research since its identification in 1924. This process involves elevated glucose uptake and lactate production, even in the presence of oxygen, supporting rapid cell ...
Dr. T. Shehnaz Begum, Prof Dr. Ammar A. Razzak Mahmood, Maya Prabhakaran Pillai V, Dr. John Abraham, Dr. Vanitha Innocent Rani, Amutha Chellathurai, Dr. Somenath Ghosh   +6 more
openaire   +1 more source

Understanding the Warburg Effect

, 2012
This senior integrative exercise explores the current knowledge surrounding the genetic causes and metabolic effects of the Warburg effect in cancer ...
Amaefuna, Steve C.
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