Results 141 to 150 of about 53,058 (296)

Impurity Tolerance in LiFePO4 Cathodes: Contrasting Structural, Electronic, and Electrochemical Roles of Residual Ni and Cr

Advanced Science, EarlyView.
Impurity tolerance in LiFePO4 cathodes varies strongly with impurity type and content. Low Ni levels are accommodated within the lattice with minimal structural disruption, whereas higher Ni contents introduce antisite disorder. In contrast, Cr impurities segregate from the LiFePO4 framework, blocking lithium‐ion pathways and leading to inferior ...
Minjin Kim, Hyerin Jeon, Jinhee Lee, Jinsub Choi   +3 more
wiley   +1 more source

High Fracture Toughness of 1D Copper‐Based MOP Electrode Enables Fast‐Charging Lithium‐Ion Batteries

Advanced Science, EarlyView.
Traditional electrode materials suffer from particle cracking and rapid capacity fade during fast charging, largely originating from their low fracture toughness. This work introduces a one‐dimensional Cu‐based metal–organic polymer, in which strong π‐d conjugation and π–π stacking endow the framework with high fracture toughness, simultaneously ...
Mingli Li, Zhenzhen Wu, Pan Yang, Di Zhao, Mengyang Dong, Muhammad Tayyab Ahsan, Lei Zhang, Shanqing Zhang, Yun Wang   +8 more
wiley   +1 more source

K+‐Triggered Defect Engineering and Proton‐Coupled Storage in V2O5·nH2O for Advanced Zn‐Ion Thin‐Film and Microbatteries

Advanced Science, EarlyView.
K+ pre‐intercalation in V2O5·nH2O induces interlayer contraction, oxygen‐vacancy formation, and mixed‐valence states, activating defect‐mediated proton‐dominated transport. This enables cooperative H+/Zn2+ storage with enhanced kinetics and stability. The resulting Zn‐based thin‐film and microbatteries deliver high areal energy and capacity, offering a
Jingli Luo, Sanat Nalini Paltasingh, Bastola Narayan, Yijia Zhu, Debashish Das, Shuhui Li, Firoz Alam, Subhra R. Pattanayak, Sijin Liu, Tharangattu N. Narayanan, Georgios Nikiforidis, Gopinathan Sankar, Ivan P. Parkin, Saroj Kumar Nayak, Buddha Deka Boruah   +14 more
wiley   +1 more source

Cancer metabolism: The Warburg effect today

Experimental and Molecular Pathology, 2010
One of the first studies on the energy metabolism of a tumour was carried out, in 1922, in the laboratory of Otto Warburg. He established that cancer cells exhibited a specific metabolic pattern, characterized by a shift from respiration to fermentation, which has been later named the Warburg effect.
openaire   +2 more sources

CEBPG‐Mediated Palmitic Acid Adaptation of Cancer‐Associated Fibroblasts Drives Metastasis of Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study reveals a metabolic signaling axis in the OSCC microenvironment where palmitic acid (PA) drives the activation of CAFs. PA uptake triggers CEBPG‐dependent epigenetic remodeling to upregulate ERN1 and TMBIM6, thereby mitigating ER stress. This adaptive program sustains CAF survival and the pro‐metastatic phenotype, establishing this pathway ...
Yiling Duan, Yitong Li, Yufei Wu, Xiao Yang, Rui Li, Hui Zhao, Zhengjun Shang   +6 more
wiley   +1 more source

Synergistic 3D Porous Architectures and Halogen Redox Chemistry for High‐Energy and High‐Power Microbatteries

Advanced Science, EarlyView.
3D porous Ni scaffolds with PANI cathode, Zn anode, and halogen redox chemistry synergistically enhance on‐chip microbattery performance by improving active material loading, Zn2+ diffusion, and charge‐transfer kinetics. The resulting 3D Zn//I2 microbatteries deliver high areal capacity, high energy and power density, and excellent cycling stability ...
Yijia Zhu, Monojit Mondal, Xiaopeng Liu, Nibagani Naresh, Firoz Alam, Mingqing Wang, Buddha Deka Boruah   +6 more
wiley   +1 more source

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo, Rong Hu, Yuhang Hu, Ping Hu, Shengbo Han, Guozheng Lv, Zhu Zeng, Yong Zhao, Yang Li, Yan Huang, Yingsong Zhao, Hongda Wang, Guangyu Zhao, Eryang Zhao, Gang Zhao   +14 more
wiley   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Tumor Microenvironment‐Responsive Nanoreactor Induces Disulfidptosis in Pancreatic Cancer via Metabolic Interference and Redox Catalysis

Advanced Science, EarlyView.
Schematic illustration of a tumor microenvironment‐responsive nanoreactor for imaging‐guided induction of disulfidptosis in pancreatic cancer via metabolic interference and redox catalysis. (A) Stepwise fabrication of Pht@HMnO2‐HA, including MnO2 growth on a SiO2 template, template removal to form hollow mesoporous MnO2, Pht loading, and subsequent ...
Rui Fu, Qing Li, Guanzhong Zhao, Qingyan Gao, Huantong Chen, Khemayanto Hidayat, Jiaying Xu, Liqiang Qin, Chunhong Hu, Yu Chong, Su Hu   +10 more
wiley   +1 more source