Results 91 to 100 of about 59,616 (308)

Thiamine Acquisition Strategies Impact Metabolism and Competition in the Gut Microbe Bacteroides thetaiotaomicron. [PDF]

, 2017
Thiamine (vitamin B1) is an essential cofactor for all organisms. Humans primarily acquire thiamine through their diet, and thiamine deficiencies have adverse neurological effects.
Costliow, Zachary A, Degnan, Patrick H
core  

Push-pull bithiophene azo-chromophores bearing thiazole and benzothiazole acceptor moieties: synthesis and evaluation of their redox and nonlinear optical properties [PDF]

, 2011
Three series of bithiophene azo dyes functionalized with thiazol-2-yl or benzothiazol-2-yl-diazene acceptor moieties were synthesized through azo coupling reaction using 2,2´-bithiophene, 5-alkoxy-2,2´-bithiophenes, 5-N,N-dialkylamino-2,2´-bithiophenes ...
Belsley, M., Castro, M. Cidália R., Fonseca, A. Maurício C., Raposo, M. Manuela M.   +3 more
core   +1 more source

Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells

Chemistry – A European Journal, EarlyView.
We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu, Kunihiko Morihiro, Rui Cong, Samruddhi Maheshwar Patil, Idoia Wille, Akimitsu Okamoto   +5 more
wiley   +1 more source

Bistratamides M and N, Oxazole-Thiazole Containing Cyclic Hexapeptides Isolated from Lissoclinum bistratum Interaction of Zinc (II) with Bistratamide K [PDF]

, 2017
[Abstract] Two novel oxazole-thiazole containing cyclic hexapeptides, bistratamides M (1) and N (2) have been isolated from the marine ascidian Lissoclinum bistratum (L. bistratum) collected in Raja Ampat (Papua Bar, Indonesia). The planar structure of 1
Cuevas, Carmen, Fernández, Rogelio, Jiménez, Carlos, Pérez, Marta, Rodríguez, Jaime, Urda, Carlos   +5 more
core   +3 more sources

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Ranking ligand affinity for the DNA minor groove by experiment and simulation [PDF]

, 2010
The structural and thermodynamic basis for the strength and selectivity of the interactions of minor-groove binders (MGBs) with DNA is not fully understood.
Anthony N. G., Anthony N. G., Anthony N. G., Bailly C., Chaires J. B., Dervan P. B., Duan Y., Feig M., Freyer M. W., Hamdan I., Hawkins G. D., James P. L., Khalaf A. I., Kopka M. L., Kopka M. L., Lane A. N., Misra V. K., Mrksich M., Patel D. J., Pelton J. G., Syme N. R., Trauger J. W., Treesuwan W., Wade W. S., Wittayanarakul K.   +24 more
core   +2 more sources

Mid‐Infrared Spectroscopy and Machine Learning for Chlorogenic Acid Quantification in Coffee

Chemie Ingenieur Technik, EarlyView.
Chlorogenic acid (CGA) concentration in coffee was predicted using mid‐infrared (MIR) spectroscopy and a machine learning approach. Forty‐four roasting stages (140–220 °C) plus a green coffee control were analyzed. A multilayer perceptron regressor, trained on preprocessed MIR data, outperformed traditional peak analysis, enabling accurate and ...
Deborah Herdt, Felix Wühler, Thomas Kunz, Victoria Schiwek, Sarah Kühnemuth, Brian Gibson, Matthias Rädle   +6 more
wiley   +1 more source

Crystal structures of 6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione and 5′-methyl-6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compounds, C20H16N2O3S, (I), and C21H18N2O3S, (II), differ by the presence of a methyl group in position 5 on the 1H-indole-2-one ring of compound (II). The two compounds have a structural overlap r.m.s. deviation of 0.48 Å.
S. Pangajavalli, R. Ranjithkumar, N. Srinivasan, S. Ramaswamy, S. Selvanayagam   +4 more
doaj   +1 more source

Oxazole and thiazole analogs of sulindac for cancer prevention [PDF]

, 2018
Aim: Experimental and epidemiological studies and clinical trials suggest that nonsteroidal anti-inflammatory drugs possess antitumor potential. Sulindac, a widely used nonsteroidal anti-inflammatory drug, can prevent adenomatous colorectal polyps and ...
Connelly, Michele C., Guy, R. Kiplin, Hobrath, Judith V., Mathew, Bini, Reynolds, Robert C.   +4 more
core   +2 more sources

On the Vapor Pressures, Phase Transitions, and Solid‐State Fluorescence of 2‐(2‐Hydroxyphenyl)benzoxazole and 2‐(2‐Hydroxyphenyl)benzothiazole

ChemPhysChem, EarlyView.
Benzazoles 2‐(2‐hydroxyphenyl)benzothiazole and 2‐(2‐hydroxyphenyl)benzoxazole exhibit tunable optoelectronic properties via excited‐state intramolecular proton transfer. Combining thermogravimetry (TG‐DSC), vapor pressure measurements, and fluorescence spectroscopy, how sulfur (S) versus oxygen (O) substitution dictates their stability, sublimation ...
José M. Silva Ferraz, Ana L. R. Silva, Lorenza Romagnoli, Andrea Ciccioli, Vera L. S. Freitas, Maria D. M. C. Ribeiro da Silva, Stefano Vecchio Ciprioti   +6 more
wiley   +1 more source