Results 121 to 130 of about 67,735 (340)

Design and Synthesis of Oxazoline-Based Scaffolds for Hybrid Lewis Acid/Lewis Base Catalysis of Carbon–Carbon Bond Formation [PDF]

, 2016
A new class of hybrid Lewis acid/Lewis base catalysts has been designed and prepared with an initial objective of promoting stereoselective direct aldol reactions.
Benoit, Adam R., Dockendorff, Chris, Porter, Jacob D., Shanaa, Alaa, Virdi, Rajdeep S., Wiedenhoeft, Dennis, Wu, Yibiao   +6 more
core   +1 more source

Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides. [PDF]

, 2017
A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl ...
Gu, Yang, Gu, Yucheng, Lu, Changhui, Shen, Qilong, Wu, Jiang   +4 more
core   +1 more source

Oxidative Dehydrogenation of N‐Heteroaromatic Alkyl Alcohols and Amines Facilitated by Dearomative Tautomerization

Chemistry – A European Journal, EarlyView.
N‐heteroaromatic alkyl alcohols and amines are inherently unstable in acidic and/or basic solution due to an irreversible dehydrogenation that proceeds from a minority tautomer. In many cases, this reaction results in quantitative oxidation to the corresponding aldehyde, providing a simple, convenient, and green approach for preparing versatile ...
Omid Ghasemloo, Carson L. Hasselbrink, Douglas D. Cardona, Brenton DeBoef, Dugan Hayes   +4 more
wiley   +1 more source

Synthesis and in Vitro Evaluation of New Nitro-Substituted Thiazolyl Hydrazone Derivatives as Anticandidal and Anticancer Agents

Molecules, 2014
Fourteen new thiazolyl hydrazone derivatives were synthesized and evaluated for their anticandidal activity using a broth microdilution assay. Among the synthesized compounds, 2-[2-((5-(4-chloro-2-nitrophenyl)furan-2-yl)methylene)hydrazinyl]-4-(4 ...
Mehlika Dilek Altıntop, Ahmet Özdemir, Gülhan Turan-Zitouni, Sinem Ilgın, Özlem Atlı, Fatih Demirci, Zafer Asım Kaplancıklı   +6 more
doaj   +1 more source

Bithiazole: An Intriguing Electron-Deficient Building for Plastic Electronic Applications. [PDF]

, 2017
The heterocyclic thiazole unit has been extensively used as electron-deficient building block in π-conjugated materials over the last decade. Its incorporation into organic semiconducting materials is particularly interesting due to its structural ...
Al-Hashimi, Ando, Ando, Balan, Baumgartner, Berlin, Brabec, Brabec, Brondijk, Bronstein, Calhoun, Cao, Cho, Cho, Cunningham, Dennler, Dutta, Dutta, Facchetti, Fan, Fu, Getmanenko, Guo, Guo, Guo, Guo, Guo, He, Heyd, Heyd, Heyd, Holliday, Hou, Hu, Huang, Huang, Ie, Jesper, Jung, Jung, Kim, Kudla, Lee, Lee, Lee, Lee, Li, Li, Li, Lin, Lin, Liu, Liu, Liu, Loewe, Lu, Lu, Moon, Oniwa, Ortiz, Paek, Pammer, Pammer, Patra, Patra, Shen, Shi, Sirringhaus, Sirringhaus, Stalder, Tada, Tam, Usta, Wang, Wang, Wang, Wong, Wong, Xia, Yanai, Ying, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zheng, Zhou, Zotti   +93 more
core   +2 more sources

6′-(3-Bromophenyl)-7′-nitro-1′,6′,7′,7a'-tetrahydro-3′H-spiro[indeno[1,2-b]quinoxaline-11,5′-pyrrolo[1,2-c]thiazole]

IUCrData, 2018
The title compound, C26H19BrN4O2S, crystallizes in a monoclinic C-centred lattice with eight molecules in the unit cell. The five-membered thiazole and pyrrolidine rings adopt envelope conformations and the bromophenyl and indenoquinoxaline planes are ...
C. Muthuselvi, M. Muthu, S. Athimoolam, B. Ravikumar, S. Pandiarajan, R. V. Krishnakumar   +5 more
doaj   +1 more source

From Donor-Acceptor Ligands to Smart Coordination Polymers: Cyanothiazole-Cu(I) Complexes for Multifunctional Electronic Devices. [PDF]

Chemistry
Cyanothiazoles, paired with copper(I) iodide, form complexes with luminescent properties. X‐ray crystallography revealed two types of coordination polymers, while spectroscopic, synchrotron, and electric measurements supported by density functional (DFT) calculations studies highlighted their unique electronic features, offering a foundation for future
Gutmańska K, Podborska A, Mazur T, Sławek A, Sivasamy R, Maximenko A, Orzeł Ł, Oszajca J, Stochel G, Dev AV, Vijayakumar C, Szaciłowski K, Dołęga A.   +12 more
europepmc   +2 more sources

Antimicrobial activity, synergism and inhibition of germ tube formation by Crocus sativus-derived compounds against Candida spp [PDF]

, 2016
The limited arsenal of synthetic antifungal agents and the emergence of resistant Candida strains have prompted the researchers towards the investigation of naturally occurring compounds or their semisynthetic derivatives in order to propose new ...
ANGIOLELLA, Letizia, CARRADORI, Simone, CHIMENTI, Paola, Fazzari, Marina, GRANESE, ARIANNA   +4 more
core   +2 more sources

Is Mycobacterial InhA a Suitable Target for Rational Drug Design?

ChemMedChem, EarlyView.
InhA is the target of isoniazid, a first‐line antituberculosis drug. Isoniazid is, in fact, a prodrug that needs to be activated. Researchers are trying to develop direct inhibitors of InhA. This includes the resolution of crystallographic structures. The Protein Data Bank contains over a hundred InhA structures.
Julien Rizet, Laurent Maveyraud, David Rengel, Valérie Guillet, Gabriel Publicola, Frédéric Rodriguez, Christian Lherbet, Lionel Mourey   +7 more
wiley   +1 more source

SYNTHESIS AND ANTIMICROBIAL ACTIVITY EVALUATION OF SOME SCHIFF BASES DERIVED FROM 2-AMINOTHIAZOLE DERIVATIVES

Indonesian Journal of Pharmacy, 2013
Various substituted acetophenones (1-5) on treatment with iodine and thiourea yielded 2-amino-4-(substituted-phenyl)-thiazole (1a-5a), which on further treatment with various substituted aldehydes to get N-(substitutedbenzylidene)-4-(substitutedphenyl ...
Rajul Gupta, Neeraj Kumar Fuloria, Shivkanya Fuloria   +2 more
doaj   +1 more source