Molecular modeling and docking of new 2-acetamidothiazole-based compounds as antioxidant agents
The highly versatile, 2-chloroacetamido-5-(4-chlorophenylazo)thiazole (2) was synthesized and used as a precursor for the production of five 2-(2-substitutedacetamido)thiazole compounds by its reaction with different types of nucleophiles such as ...
Sraa Abu-Melha
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Expected and unexpected products of reactions of 2-hydrazinylbenzothiazole with 3-nitrobenzenesulfonyl chloride in different solvents [PDF]
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the X-ray data collections.
de Souza, Marcus V. N. +3 more
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Demethylation and desulfonation of textile industry dye, Thiazole Yellow G by Aspergillus niger LAG
Filamentous fungi perform tremendously in adsorption of dyes from polluted environment. In this study, Aspergillus niger LAG decolorized thiazole yellow G dye within 5 days. Scale up studies done revealed that maximum decolorization (98%) was achieved at
Paul O. Bankole +2 more
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Thiazole, triazole, thio and semicarbazones are privileged motifs that act as pharmacophores in bioactive compounds for various diseases, such as Tuberculosis (TB).
Cauê Benito Scarim +1 more
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Methyl 2-amino-5-isopropyl-1,3-thiazole-4-carboxylate [PDF]
The title compound, C8H12N2O2S, forms a supramolecular network based on N-HN hydrogen-bonded centrosymmetric dimers that are linked in turn by N-HO ...
Kennedy, Alan R. +3 more
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Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus [PDF]
Aim: The only small molecule drugs currently available for treatment of influenza A virus (IAV) are M2 ion channel blockers and sialidase inhibitors. The prototype thiazolide, nitazoxanide, has successfully completed Phase III clinical trials against ...
Andrew V Stachulski +17 more
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A series of new thiazole-based stilbene analogs were designed, synthesized and evaluated for DNA topoisomerase IB (Top1) inhibitory activity. Top1-mediated relaxation assays showed that the synthesized compounds possessed variable Top1 inhibitory ...
Jin-Chuan Liu +5 more
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Polysaccharide‐Coated
ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares +4 more
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Optimized gating and reference ranges of reticulated platelets in dogs for the Sysmex XT-2000iV [PDF]
Background: Canine reticulated platelets (r-PLTs) i.e., juvenile PLTs reflecting thrombopoiesis can be measured automatically with the hematology analyzer Sysmex XT-2000iV using manual gating options.
Bauer, Natali +5 more
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2-(Benzothiazol-2-ylsulfanyl)acetic acid
In the title compound, C9H7NO2S2, the benzine ring is essentially co-planar with the thiazole ring, making a dihedral angle of 0.36 (7)°. In the crystal structure, molecules are linked by intermolecular O—H...N hydrogen bonds
Zhi-li Fang, Jun Wang
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