Results 31 to 40 of about 67,735 (340)

Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport [PDF]

, 2014
A potent class of indolinyl-thiazole based inhibitors of cellular lipid uptake mediated by scavenger receptor, class B, type I (SR-BI) was identified via a high-throughput screen of the National Institutes of Health Molecular Libraries Small Molecule ...
Bennion, Melissa, Dandapani, Sivaraman, Dockendorff, Chris, Faloon, Patrick W., Krieger, Monty, Lam, Garrett, Lewis, Timothy A., Munoz, Benito, Nag, Partha P., Negri, Joseph, Nieland, Thomas J.F., Palmer, Michelle A., Paterson, Conor, Penman, Marsha, Perez, José R., Pu, Jun, Schreiber, Stuart L., Youngsaye, Willmen, Yu, Miao   +18 more
core   +3 more sources

Synthesis of Stable Thiazole-Linked Covalent Organic Frameworks via a Multicomponent Reaction.

Journal of the American Chemical Society, 2020
The development of robust synthetic routes to stable covalent organic frameworks (COFs) is important to broaden the range of applications for these materials.
Kewei Wang, Z. Jia, Yang Bai, Xue Wang, Sophie E. Hodgkiss, Linjiang Chen, S. Chong, Xiaoyan Wang, Haofan Yang, Yongjie Xu, Feng Feng, J. W. Ward, A. Cooper   +12 more
semanticscholar   +1 more source

Polymorphism in metal complexes of thiazole-4-carboxylic acid [PDF]

, 2016
Five new molecular complexes of chemical formula [M(4-tza)₂(H₂O)₂] (M = Co, Ni, and Cu) and a complex of [Cu(4-tza)₂]∙4H₂O using thiazole-4-carboxylic acid (4-tza) as the ligand have been successfully synthesized and structurally characterized by single ...
Meundaeng, Natthaya, Prior, Timothy J., Rujiwatra, Apinpus   +2 more
core   +1 more source

Activity of antioxidant enzymes in hepatocytes of mice with lymphoma under the action of thiazole derivative in complex with polymeric nanocarrier

Біологія тварин, 2023
Many chemotherapeutics drugs have low water solubility, which potentially can decrease their anticancer potential. The use of drug delivery systems has proven to be highly effective in addressing the challenges associated with delivering hydrophobic ...
B. Omeliukh, Ya. Shalai, M. Bura, M. Ilkiv, Yu. Ostapiuk, N. Mitina, O. Zaichenko, A. Babsky   +7 more
doaj   +1 more source

Intermolecular C-H...N and C-H...O interactions in (2S,4S,5R)-(-)-3,4-dimethyl-5-phenyl-2-(1,3-thiazol-2-yl)-1,3-oxazolidine [PDF]

, 1999
The title compound, C₁₄H₁₆N₂OS, prepared from (1R,2S)-(-)-ephedrine, contains the oxazolidine ring in an envelope conformation, with the nitrogen atom 0.623 (2) Å from the plane of the other four oxazolidine ring atoms. Intermolecular C--H...N and C--
Fitzsimons, Lavelle M., Gallagher, John F.   +1 more
core   +1 more source

Antibacterial Activity of Thiazole and its Derivatives: A Review

Biointerface Research in Applied Chemistry, 2021
Thiazoles are one of the most intensively scrutinized classes of 5-membered aromatic heterocycles. Many natural and synthesized thiazole and its derivatives showed significant biological activity.
P. Mohanty, Sunita Behera, R. Behura, Lipsa Shubhadarshinee, Priyaranjan Mohapatra, A. K. Barick, B. R. Jali   +6 more
semanticscholar   +1 more source

Molecular mechanisms of the non-coenzyme action of thiamin in brain. Biochemical, structural and pathway analysis [PDF]

, 2015
Thiamin (vitamin B1) is a pharmacological agent boosting central metabolism through the action of the coenzyme thiamin diphosphate (ThDP). However, positive effects, including improved cognition, of high thiamin doses in neurodegeneration may be ...
Andrey, Vovk, Contestabile, Roberto, DI SALVO, Martino Luigi, Garik, Mkrtchyan, Lucien, Bettendorff, Parroni, Alessia, Thilo, Kaehne, Vasily, Aleshin, Victoria, Bunik, Yulia, Parkhomenko   +9 more
core   +1 more source

Thiazoles in Peptides and Peptidomimetics [PDF]

, 2015
The natural occurrence of the thiazole ring in chemistry and biology has inspired its widespread use in synthetic peptidomimetics as structural templates, biological probes, and pharmaceuticals. Thiazole can be viewed as a dehydrated cyclized derivative of cysteine, incorporated into peptide sequences through chemical synthesis or ribosomal ...
Mak, Jeffrey Y. W., Xu, Weijun, Fairlie, David P.   +2 more
openaire   +3 more sources

A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole Tautomerase [PDF]

Journal of the American Chemical Society, 2011
In many bacteria tenI is found clustered with genes involved in thiamin thiazole biosynthesis. However, while TenI shows high sequence similarity with thiamin phosphate synthase, the purified protein has no thiamin phosphate synthase activity, and the role of this enzyme in thiamin biosynthesis remains unknown.
Abhishek Chatterjee, Rung-Yi Lai, Steven E. Ealick, Ying Han, Amrita B. Hazra, Tadhg P. Begley, Yang Zhang   +6 more
openaire   +3 more sources

Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides

Heteroatom Chemistry, 2017
AbstractThis research reports a novel method for synthesizing new thiazole thioglycosides. This series of thiazole thioglycosides were designed by the reaction of potassium cyanocarbonimidodithioate 2 with benzoyl acetonitrile 3a and ethyl bromoacetate 3b in the presence of ethanol‐KOH to give the corresponding potassium 4‐amino‐5‐substituted‐thiazole ...
Mamdouh A. Abu‐Zaied, Galal H. Elgemeie   +1 more
openaire   +2 more sources