Results 31 to 40 of about 59,616 (308)

2-[5-(Benzo[d]thiazol-2-yl)thiophen-2-yl]benzo[d]thiazole

Acta Crystallographica Section E, 2010
The structure of the title compound, C18H10N2S3, consists of a central thiophene ring and two terminal thiazole rings. The two S atoms of the thiazole rings are trans to the thiophene S atom sulfur.
Thomas I. A. Gerber, Eric Hosten, Peter Mayer, Kim Potgieter   +3 more
doaj   +1 more source

Synthesis and Antiproliferative Potential of Thiazole and 4-Thiazolidinone Containing Motifs as Dual Inhibitors of EGFR and BRAF^V600E

Molecules, 2023
Thiazole and thiazolidinone recur in a wide range of biologically active compounds that reach different targets within the context of tumors and represent a promising starting point to access potential candidates for treating metastatic cancer. Therefore,
Alaa A. Hassan, Nasr K. Mohamed, Ashraf A. Aly, Mohamed Ramadan, Hesham A. M. Gomaa, Ahmed T. Abdel-Aziz, Bahaa G. M. Youssif, Stefan Bräse, Olaf Fuhr   +8 more
doaj   +1 more source

One-Pot Chemoenzymatic Multicomponent Synthesis of Thiazole Derivatives

Molecules, 2013
A novel chemoenzymatic one-pot multicomponent synthesis of thiazole derivatives was developed. A series of thiazole derivatives were synthesized with high yields up to 94% under mild enzyme-catalyzed conditions.
Hui Zheng, Yi-Jia Mei, Kui Du, Xian-Ting Cao, Peng-Fei Zhang   +4 more
doaj   +1 more source

4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis [PDF]

, 2019
A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents
Alcaro, Stefano, Bagetta, Donatella, Carradori, Simone, Chimenti, Paola, D’Ascenzio, Melissa, Guglielmi, Paolo, Ortuso, Francesco, Petzer, Anél, Petzer, Jacobus P., Secci, Daniela, Zengin, Gokhan   +10 more
core   +1 more source

Synthesis and cytotoxicity evaluation of thiazole conjugated amino acid derivatives

CTU Journal of Innovation and Sustainable Development
This paper presents the three-step synthesis and cytotoxicity evaluation of the thiazole-conjugated amino acid derivatives. Starting from the commercially available benzophenone and thiourea, the thiazole structure was successfully constructed bearing ...
Nhut Linh Huynh, Truong Giang Nguyen, Thi My Tien Nguyen, Pham Xuan Truc Nguyen, Minh Thi Bui, Trong Hieu Le, Vinh Quang Hong, Minh Kiep Do, Hiroyuki Morita, Thi Buu Hue Bui   +9 more
doaj   +1 more source

Synthesis and cytotoxicity evaluation of thiazole derivatives obtained from 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene- 3-carbonitrile

Acta Pharmaceutica, 2017
Reactivity of 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3- carbonitrile towards thioglycolic acid resulted in thiazole derivative 1. The latter reacted with different chemical reagents to give thiazole, pyrano[2,3-d]thiazole and thiazolo[ 4,5-d ...
Mohareb Rafat M., Abdallah Amira E. M., Ahmed Ebtsam A.   +2 more
doaj   +1 more source

Benzo[1,2,3]dithiazole Compounds: A History of Synthesis and Their Renewed Applicability in Materials and Synthetic Chemistry, Originating from the Herz Reaction

Reactions, 2021
The benzo[1,2,3]dithiazole is a unique heteroaromatic functionality whose conjugated profile instils some fascinating electronic properties. This has been historically recognized in the design and manufacture of organic dyes early last century. Although,
Alexander J. Nicholls, Ian R. Baxendale
doaj   +1 more source

A Rigid Polymer Donor Based on a Simple Benzodithiophene-Thiazole Backbone for Organic Photovoltaics. [PDF]

ChemSusChem
A new polymer donor, PBDTTz, with a simple benzodithiophene–thiazole backbone, features intramolecular N···S interactions that lock the backbone into a rigid, coplanar conformation and enhance π–π stacking, while the electron‐deficient thiazole units also deepen the highest occupied molecular orbital level.
Teshima Y, Yamanaka K, Sato Y, Jeon J, Saito M, Mikie T, Kim HD, Ohkita H, Osaka I.   +8 more
europepmc   +2 more sources

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells [PDF]

, 2016
Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl ...
Buglioni, Simonetta, Carradori, Simone, DE LUCA, Teresa, De Maria, Ruggero, Del Bufalo, Donatella, Desideri, Marianna, DI MARTILE, Marta, Eramo, Adriana, Gabellini, Chiara, Mai, Antonello, Milella, MICHELE STANISLAW, Rotili, Dante, Secci, Daniela, Sette, Giovanni, Trisciuoglio, Daniela   +14 more
core   +4 more sources

Synthetic Routes to Coumarin(Benzopyrone)-Fused Five-Membered Aromatic Heterocycles Built on the α-Pyrone Moiety. Part II: Five-Membered Aromatic Rings with Multi Heteroatoms

Molecules, 2021
Coumarins are natural heterocycles that widely contribute to the design of various biologically active compounds. Fusing different aromatic heterocycles with coumarin at its 3,4-position is one of the interesting approaches to generating novel molecules ...
Eslam Reda El-Sawy, Ahmed Bakr Abdelwahab, Gilbert Kirsch   +2 more
doaj   +1 more source