One-Pot Chemoenzymatic Multicomponent Synthesis of Thiazole Derivatives
A novel chemoenzymatic one-pot multicomponent synthesis of thiazole derivatives was developed. A series of thiazole derivatives were synthesized with high yields up to 94% under mild enzyme-catalyzed conditions.
Hui Zheng+4 more
doaj +1 more source
Toward eradication of B-vitamin deficiencies : considerations for crop biofortification [PDF]
'Hidden hunger' involves insufficient intake of micronutrients and is estimated to affect over two billion people on a global scale. Malnutrition of vitamins and minerals is known to cause an alarming number of casualties, even in the developed world ...
Strobbe, Simon+1 more
core +3 more sources
Department of Chemistry, Punjab University, Chandigarh-160014 Manuscript received 11 February 1974; accepted 20 August 1974 Some Pyrazolo(3,4-d)-thiazoles have been synthesised by the condensation of phenyl thioureas with 4-bromo-1,3 diphenyl pyrazolone-5. However, In each case, two products have been isolated.
H. K. GAKHAR, VED PARKASH, KUL BHUSHAN
openaire +1 more source
A novel series of some hydrazones bearing thiazole moiety were generated via solvent-drop grinding of thiazole carbohydrazide 2 with various carbonyl compounds.
Sraa Abu-Melha+5 more
semanticscholar +1 more source
Structural Basis for the Catalytic Mechanism of ATP‐Dependent Diazotase CmaA6
Several diazotases have been reported in recent years, but the detailed catalytic mechanism is unclear. From X‐ray crystallography and Cryo‐EM analysis, we obtained the structure of a diazotase CmaA6, which synthesizes 3‐diazocoumaric acid. Kinetic analysis and computational analysis indicated that CmaA6 catalyzes diazotization via an unprecedented ...
Seiji Kawai+5 more
wiley +2 more sources
Reactivity of 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3- carbonitrile towards thioglycolic acid resulted in thiazole derivative 1. The latter reacted with different chemical reagents to give thiazole, pyrano[2,3-d]thiazole and thiazolo[ 4,5-d ...
Mohareb Rafat M.+2 more
doaj +1 more source
Fluorescent turn-on probes for wash-free mRNA imaging via covalent site-specific enzymatic labeling. [PDF]
Investigating the many roles RNA plays in cellular regulation and function has increased demand for tools to explore RNA tracking and localization within cells.
Alexander, Seth C+2 more
core +2 more sources
Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells [PDF]
Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl ...
Buglioni, Simonetta+14 more
core +6 more sources
Reactivity of [Re\u3csub\u3e2\u3c/sub\u3e(CO)\u3csub\u3e8\u3c/sub\u3e(MeCN)\u3csub\u3e2\u3c/sub\u3e] with Thiazoles: Hydrido Bridged Dirhenium Compounds Bearing Thiazoles in Different Coordination Modes [PDF]
Reactions of the labile compound [Re2(CO)8(MeCN)2] with thiazole and 4-methylthiazole in refluxing benzene afforded the new compounds [Re2(CO)7{μ-2,3-η2-C3H(R)NS}{η1-NC3H2(4-R)S}(μ-H)] (1, R = H; 2, R = CH3), [Re2(CO)6{μ-2,3-η2-C3H(R)NS}{η1-NC3H2(4-R)S}2(
Ahmed, Faruque+8 more
core +1 more source
Ionization effects on the partitioning behavior of food and beverage aroma compounds between aqueous phases and air and organic matrices [PDF]
Aroma compounds in the Flavornet database were screened for ionizable functional groups such as carboxylic acids, aliphatic and aromatic amines, phenols, alcohols, and thiols.
Kaya Forest, Sierra Rayne
core +2 more sources