Results 51 to 60 of about 59,616 (308)

Polymorphism in metal complexes of thiazole-4-carboxylic acid [PDF]

, 2016
Five new molecular complexes of chemical formula [M(4-tza)₂(H₂O)₂] (M = Co, Ni, and Cu) and a complex of [Cu(4-tza)₂]∙4H₂O using thiazole-4-carboxylic acid (4-tza) as the ligand have been successfully synthesized and structurally characterized by single ...
Meundaeng, Natthaya, Prior, Timothy J., Rujiwatra, Apinpus   +2 more
core   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Design and Synthesis of Oxazoline-Based Scaffolds for Hybrid Lewis Acid/Lewis Base Catalysis of Carbon–Carbon Bond Formation [PDF]

, 2016
A new class of hybrid Lewis acid/Lewis base catalysts has been designed and prepared with an initial objective of promoting stereoselective direct aldol reactions.
Benoit, Adam R., Dockendorff, Chris, Porter, Jacob D., Shanaa, Alaa, Virdi, Rajdeep S., Wiedenhoeft, Dennis, Wu, Yibiao   +6 more
core   +1 more source

Intermolecular C-H...N and C-H...O interactions in (2S,4S,5R)-(-)-3,4-dimethyl-5-phenyl-2-(1,3-thiazol-2-yl)-1,3-oxazolidine [PDF]

, 1999
The title compound, C₁₄H₁₆N₂OS, prepared from (1R,2S)-(-)-ephedrine, contains the oxazolidine ring in an envelope conformation, with the nitrogen atom 0.623 (2) Å from the plane of the other four oxazolidine ring atoms. Intermolecular C--H...N and C--
Fitzsimons, Lavelle M., Gallagher, John F.   +1 more
core   +1 more source

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

Nucleic Acid Specificity, Cellular Localization and Reduced Toxicities of Thiazole Orange‐Neomycin Conjugates

ChemistryOpen
Selective binding of small molecule ligands to nucleic acids with high affinity and limited toxicity remains an important goal in the development of compounds that can probe DNA or RNA in cells.
Antwine W. McFarland Jr., Lawrence P. Fernando, Patrick Kellish, Sandra P. Story, Gretchen B. Schober, Sunil Kumar, Changjun Gong, Ada King, Xianchang Gong, Alain S. Leutou, Dev P. Arya   +10 more
doaj   +1 more source

Targeting DESI2 as a Novel Therapeutic Strategy for JAK2‐Mutant Leukemias

Advanced Science, EarlyView.
Mass spectrometry‐based proteomics identify DESI2 as a novel component of the JAK2‐V617F complex, which associates with and stabilizes mutant JAK2 through deSUMOylation and deubiquitination, therefore promoting JAK2 mutant cell growth and MPN disease onset in vivo.
Husheng Mei, Wuqiang Wen, Wenjun Zhang, Shujing Zhang, Ting Sun, Guiming Li, Jing Zhang, Shuang Qi, Jie Zhou, Bing Li, Yunshuo Zhao, Xiaotong Chen, Bowen Li, Yiying Xue, Wang Lu, Yanli Sun, Jingyao Wang, Hengyue Shan, Shengzhe Zhang, Yushan Huang, Yisa Chen, Wenchao Wang, Qingsong Liu, Wenchao Lu, Li Tan, Yi Ding, Jianfei Fu, Jun Long, Lei Zhang, Baobing Zhao, Aibin Liang, Baishan Jiang, Jing Yang   +32 more
wiley   +1 more source

6-Bromo-2-methylsulfanyl-1,3-benzothiazole

Acta Crystallographica Section E, 2011
The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski, Marta Struga, Daniel Szulczyk   +2 more
doaj   +1 more source

Bioactive thiazole and benzothiazole derivatives

European Journal of Medicinal Chemistry, 2015
The heterocycles are the versatile compounds existing in almost all natural products and synthetic organic compounds, usually associated with one or the other biological activity. Among the heterocycles the thiazoles and benzothiazoles occupy a prominent position.
Rouf, Abdul, Tanyeli, Cihangir
openaire   +3 more sources

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source