Results 61 to 70 of about 24,222 (188)

(E)-N′-(4-Fluorobenzylidene)-5-methyl-2-(pyridin-3-yl)thiazole-4-carbohydrazide

Molbank, 2019
5-methyl-2-(pyridin-3-yl)-1,3-thiazole-4-carbohydrazide (1) on treatment with 4-fluorobenzaldehyde in presence of catalytic amount of acetic acid, accessed the target compound (2) with the yield of 79%.
Vinuta Kamat, Rangappa Santosh, Suresh P. Nayak   +2 more
doaj   +1 more source

Indole‐Based π‐Extended Monophosphine Ligands for Enhanced Palladium‐Catalyzed Sonogashira Coupling

Journal of Heterocyclic Chemistry, EarlyView.
A general palladium‐catalyzed Sonogashira cross‐coupling of (hetero)aryl chlorides with aliphatic, (hetero)aryl alkynes is described using Pd(dba)₂/PCy2‐Napdole‐phos catalyst system. The reaction protocol exhibits broad substrate scope and the catalyst loading can be down to 0.2 mol% Pd.
Yu Kiu Lau, Chun Pong Hui, Cheuk Long Li, Ho Chung Chang, Man Ho Tse, Ho Kwan Lou, Iat In Chan, Raymond Wai‐Yin Sun, Pui Ying Choy, Fuk Yee Kwong   +9 more
wiley   +1 more source

Efficient One‐Pot Synthesis of Benzothiazole Compounds From Vinamidinium Salts

ChemistryOpen, EarlyView.
A catalyst‐free one‐pot reaction of vinamidinium salts with benzothiazole hydrazines efficiently produces 1,3‐bis((3‐methylbenzo[d]thiazol‐2(3H)‐ylidene)hydrazineylidene)propan‐2‐ol (BBTA) and 1‐((1Z,3E)‐1‐(dimethylamino)‐3‐(((Z)‐3‐methylbenzo[d]thiazol‐2(3H)‐ylidene)hydrazineylidene)prop‐1‐en‐2‐yl)pyridin‐1‐ium (DMBT) derivatives.This simple method ...
Zeinab khosravi, Abdolmohammad Mehranpour, Mohammad Reza Mohammadizadeh, Genta Kojya, Satoru Arimitsuc   +4 more
wiley   +1 more source

Synthesis of Pyrido[2,3‐d]Azolopyrimidinones: Design and Epidermal Growth Factor Receptor‐Targeted Molecular Docking Toward Novel Anticancer Leads

ChemistryOpen, EarlyView.
New pyrido[2,3‐d]azolopyrimidinones were synthesized and evaluated as potent EGFR‐targeted anticancer leads. Molecular docking and cytotoxicity studies revealed strong receptor binding and submicromolar activity, highlighting this scaffold as a promising framework for future targeted drug development.
Sobhi M. Gomha, Sami A. Al‐Hussain, Basant Farag, AbdElAziz A. Nayl, Wesam Hussein, Abdelwahed R. Sayed, Magdi E. A. Zaki   +6 more
wiley   +1 more source

Crystal structures of 6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione and 5′-methyl-6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione

Acta Crystallographica Section E: Crystallographic Communications, 2019
The title compounds, C20H16N2O3S, (I), and C21H18N2O3S, (II), differ by the presence of a methyl group in position 5 on the 1H-indole-2-one ring of compound (II). The two compounds have a structural overlap r.m.s. deviation of 0.48 Å.
S. Pangajavalli, R. Ranjithkumar, N. Srinivasan, S. Ramaswamy, S. Selvanayagam   +4 more
doaj   +1 more source

Integrating tunable LED‐induced plant responses with novel solar cell technologies for energy‐efficient agrivoltaic systems

PLANTS, PEOPLE, PLANET, EarlyView.
The increasing demand for sustainable food production requires innovative solutions that balance productivity, resource efficiency, and environmental impact. Vertical Farming Systems (VFSs) offer a promising approach; however, their high energy consumption remains challenging.
Alessio Dessì, Carlo Spampinato, Fabiano Sillo, Salvatore Valastro, Mauro Centritto, Cecilia Brunetti, Andrea Ghirardo, Jörg‐Peter Schnitzler, Alessandra Alberti, Gianna Reginato, Aurora Rizzo, Raffaella Balestrini   +11 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

4-(Benzofuran-2-yl)-2-[3-(4-chlorophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]thiazole

IUCrData, 2019
The molecule of the title compound, C26H17ClFN3OS, comprises benzofuranyl (A), thiazolyl (B), pyrazolyl (C), chlorophenyl (D) and fluorophenyl (E) ring systems. Rings A–D are almost coplanar, as indicated by the twist angles between the ring pairs A/B, B/
Gamal A. El-Hiti, Bakr F. Abdel-Wahab, Alaa Alqahtani, Amany S. Hegazy, Benson M. Kariuki   +4 more
doaj   +1 more source

Trace Element Analysis in Human Neuroblastoma Cell Spheroids Supplemented With ZnCl2 by Micro‐XRF

X-Ray Spectrometry, EarlyView.
ABSTRACT Neuroblastoma, the most common extracranial solid tumor of childhood, is responsible for ~10% of pediatric cancer deaths and has high potential for metastasis. Metals are extremely important in biological processes, and changes in their levels have been correlated with the development of cancerous growth.
J. E. P. Rosa, R. G. Leitão, G. C. Ferreira, C. Palmero, E. G. Oliveira‐Barros, M. A. Oliveira, C. G. L. Canellas, L. E. Nasciutti, D. F. Olivera, R. T. Lopes, M. J. Anjos   +10 more
wiley   +1 more source

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source