Results 81 to 90 of about 67,735 (340)

Effect of novel 2-amino-5-benzylthiazole derivative on cellular ultrastructure and activity of antioxidant system in murine lymphoma cells

Біологічні студії, 2019
The influence of newly synthesized thiazole derivative N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide on cellular ultrastructure and anti­oxidant system activity in lymphoma cells was studied in vitro. A pronounced cytotoxic action
Ya. R. Shalai, M. V. Popovych, O. R. Kulachkovskyy, V. P. Hreniukh, S. M. Mandzynets, N. S. Finiuk, A. M. Babsky   +6 more
doaj   +1 more source

1,3-Thiazole-4-carbonitrile

IUCrData, 2021
The title compound, C4H2N2S, is a 1,3-thiazole substituted in the 4-position by a nitrile group. In the crystal, C—H...N hydrogen bonds and aromatic π–π stacking interactions are observed.
Martin J. G. Fait, Anke Spannenberg, Evgenii V. Kondratenko, David Linke   +3 more
doaj   +1 more source

Second-generation nitazoxanide derivatives: thiazolides are effective inhibitors of the influenza A virus [PDF]

, 2018
Aim: The only small molecule drugs currently available for treatment of influenza A virus (IAV) are M2 ion channel blockers and sialidase inhibitors. The prototype thiazolide, nitazoxanide, has successfully completed Phase III clinical trials against ...
Andrew V Stachulski, Brian M Eklov, Chandrakala Pidathala, Eleanor C Row, Giuseppe Belardo, J Edward Semple, Jean-Francois Rossignol, La Frazia S, M Gabriella Santoro, Mazhar Iqbal, Neil G Berry, Paul M O'Neill, Podlogar BL, Rossignol JF, Rossignol JF, Sara Piacentini, Sarah A Allman, Simone La Frazia   +17 more
core   +1 more source

New Series of Thiazole Derivatives: Synthesis, Structural Elucidation, Antimicrobial Activity, Molecular Modeling and MOE Docking

Molecules, 2019
Based on the extensive biological activities of thiazole derivatives against different types of diseases, we are interested in the effective part of many natural compounds, so we synthesized a new series of compounds containing di-, tri- and ...
I. Althagafi, Nashwa M. El‐Metwaly, T. Farghaly   +2 more
semanticscholar   +1 more source

Green synthesis of highly functionalized octahydropyrrolo[3,4-c]pyrrole derivatives using subcritical water, and their anti(myco)bacterial and antifungal activity [PDF]

, 2018
A series of novel 2-(thiazol-2-yl)-octahydropyrrolo[3,4-c]pyrroles was synthesized by reaction of octahydropyrrolo[3,4-c]pyrrole N-benzoylthiourea derivatives and α-haloketones in subcritical water at 130 °C in 75-91% yield.
De Coen, Laurens, Gemili, Muge, Nural, Yahya, Ulger, Mahmut, Yabalak, Erdal   +4 more
core   +1 more source

ChemInform Abstract: Bioactive Thiazole and Benzothiazole Derivatives

ChemInform, 2015
AbstractReview: [90 refs.
Rouf, Abdul, Tanyeli, Cihangir
openaire   +5 more sources

6-Bromo-2-methylsulfanyl-1,3-benzothiazole

Acta Crystallographica Section E, 2011
The title molecule, C8H6BrNS2, is almost planar with a dihedral angle of 0.9 (1)° between the benzene and thiazole rings. The values of the geometry-based index of aromaticity (HOMA) and the nucleus-independent chemical shift (NICS ...
Michał A. Dobrowolski, Marta Struga, Daniel Szulczyk   +2 more
doaj   +1 more source

closo‐Carboranyl Analogs of β‐Arylethylamines: Direct Synthesis from Alkenes via EnT‐Catalysis

Angewandte Chemie International Edition, EarlyView.
A strategy to directly synthesize closo‐carboranyl analogs of medicinal chemically important β‐arylethylamines from alkenes is reported. This reaction is enabled by the first formation of closo‐carboranyl radicals by energy transfer (EnT) catalysis and its unique mechanistic features.
Fritz Paulus, Corinna Heusel, Marc Jaspers, Lilli M. Amrehn, Florian Schreiner, Debanjan Rana, Constantin G. Daniliuc, Michael Ryan Hansen, Frank Glorius   +8 more
wiley   +1 more source

Study of Antibacterial Effect of Novel Thiazole, Imidazole and Tetrahydropyridine Derivatives against Escherichia coli

Journal of Medical Bacteriology, 2015
Background: Escherichia coli is one of the important pathogens in human with global importance. Because of the necessity for identification and the use of novel antibacterial compounds against E.
Behzad Ghasemi, Hamid Beyzaei, Seyed Hadi Hashemi, Hamidreza Majidiani   +3 more
doaj  

Thiazole ring- the antimicrobial, anti-inflammatory, and anticancer active scaffold

Arabian Journal of Chemistry, 2023
Background: Thiazole ring is one of the most important heterocycle scaffolds in organic and medicinal chemistry due to this scaffold being the backbone of numerous drugs and their significant activities against various diseases have made it one of the ...
Seyedmohammad Hosseininezhad, Ali Ramazani   +1 more
doaj