Results 141 to 150 of about 44,050 (359)

Optimizing Odorants for Olfactory Training Based on Olfactory Receptor–Ligand Pair Analysis

The Laryngoscope, EarlyView.
This study employs receptor–ligand interaction analysis and olfactory epithelium transcriptomics to optimize olfactory training (OT). A novel four‐odorant combination (galaxolide, eugenol acetate, [−]‐menthol, geranyl acetate) activates 83.9% of 385 human olfactory receptors (ORs), covering 69.9% of estimated OR expression—significantly outperforming ...
Hironobu Nishijima, Eric H. Holbrook, James E. Schwob, Eri Mori, Ryoji Kagoya, Kei Ogawa, Kyohei Horikiri, Kenji Kondo   +7 more
wiley   +1 more source

The Trials and Tribulations of Structure Assisted Design of KCa Channel Activators. [PDF]

, 2019
Calcium-activated K+ channels constitute attractive targets for the treatment of neurological and cardiovascular diseases. To explain why certain 2-aminobenzothiazole/oxazole-type KCa activators (SKAs) are KCa3.1 selective we previously generated ...
Brown, Brandon M, Fettinger, James C, Shim, Heesung, Singh, Latika, Singh, Vikrant, Wulff, Heike, Yarov-Yarovoy, Vladimir   +6 more
core  

Stepwise cycloaddition reaction of N-phenacylbenzothiazolium bromides and nitroalkenes for tetrahydro-, dihydro- and benzo[d]pyrrolo[2,1-b]thiazoles

Scientific Reports, 2017
The triethylamine promoted stepwise 1,3-dipolar cycloaddition reaction of N-phenacylbenzothiazolium bromides with nitroalkenes in ethanol resulted in a mixture of two isomeric tetrahydrobenzo[d]pyrrolo[2,1-b]thiazoles with cis/trans/cis- and all-trans ...
Gong Jin, Jing Sun, Ren‐Yin Yang, Chaoguo Yan   +3 more
semanticscholar   +1 more source

An ecological framework for microbial metabolites in the ocean ecosystem

Limnology and Oceanography Letters, EarlyView.
Abstract The ocean microbe‐metabolite network involves thousands of individual metabolites that encompass a breadth of chemical diversity and biological functions. These microbial metabolites mediate biogeochemical cycles, facilitate ecological relationships, and impact ecosystem health. While analytical advancements have begun to illuminate such roles,
Bryndan P. Durham, Winifred M. Johnson, Catherine C. Bannon, Erin M. Bertrand, Anitra E. Ingalls, Bethanie R. Edwards, Amy Apprill, Angela K. Boysen, Randelle M. Bundy, Huan Chen, Frank X. Ferrer‐González, Cara Fiore, Katherine R. Heal, Constanze Kuhlisch, Shuting Liu, Kaijun Lu, Laurel E. Meke, Sammy Pontrelli, Prabavathy Vaiyapuri Ramalingam, Alicia M. Reigel, Joshua S. Sacks, Jeremy E. Schreier, Jegan Sekar, Mario Uchimiya, Elizabeth B. Kujawinski   +24 more
wiley   +1 more source

Versatile Direct (Hetero)Arylation Polymerization of Electro‐Deficient Unsubstituted Thiazolo[5,4‐d]Thiazole: A Tool to Lower the LUMO Level

Macromolecular Rapid Communications, EarlyView.
An unsubstituted thiazolo[5,4‐d]thiazole (TzTz) unit is used to synthesize a series of novel semiconducting polymers via eco‐friendly direct arylation polymerization. These TzTz‐based copolymers, with various electron‐withdrawing comonomers, display optical bandgaps of 1.5–2.0 eV and strong thermal stability.
Badr Jismy, Pablo Durand, Jasmine P. Jacob, Fanny Richard, Olivier Boyron, Benoit Heinrich, Bruno Schmaltz, Patrick Lévêque, Olivier Bardagot, Nicolas Leclerc   +9 more
wiley   +1 more source

Origin and characterization of cyclodepsipeptides: Comprehensive structural approaches with focus on mass spectrometry analysis of alkali‐cationized molecular species

Mass Spectrometry Reviews, EarlyView.
Abstract Cyclodepsipeptides (CDPs) represent a huge family of chemically and structurally diverse molecules with a wide ability for molecular interactions. CDPs are cyclic peptide‐related natural products made up of both proteinogenic and nonproteinogenic amino acids linked by amide and ester bonds.
Sophie Liuu, Annelaure Damont, Alain Perret, Olivier Firmesse, François Becher, Gwenaëlle Lavison‐Bompard, Amandine Hueber, Amina S. Woods, Ekaterina Darii, François Fenaille, Jean‐Claude Tabet   +10 more
wiley   +1 more source

The influence of volatile compounds of the flavour of raw, boiled and baked potatoes: Impact of agricultural measures on the volatile components [PDF]

, 2009
In dem Beitrag werden die Entstehungswege flüchtiger Verbindungen in rohen, gekochten und gebackenen Kartoffeln und deren Bedeutung für das Kartoffelaroma aufgezeigt.
Böhm, Herwart, Dresow, Jana F.
core  

The effect of N‐oxide phenazine producer Lysobacter antibioticus on bacterial leaf streak in rice and the rhizosphere microbial community

New Plant Protection, EarlyView.
Lysobacter antibioticus OH13 and its antibiotic myxin effectively control rice bacterial leaf streak (BLS) under greenhouse conditions and in field trials. OH13 alters the rhizosphere microbiome, enriching beneficial bacteria. Myxin production was boosted 3.19‐fold via mutagenesis and optimization, highlighting the potential of OH13 as a sustainable ...
Junjing Chen, Xinyi Cheng, Gaoge Xu, Yancun Zhao, Fengquan Liu, Yangyang Zhao   +5 more
wiley   +1 more source

Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study

Drug Design, Development and Therapy, 2021
Sobhi M Gomha,1,2 Hyam A Abdelhady,2 Doaa ZH Hassain,2 Aboubakr H Abdelmonsef,3 Mohamed El-Naggar,4 Mahmoud M Elaasser,5 Huda K Mahmoud2 1Chemistry Department, Faculty of Science, Islamic University in Almadinah Almonawara, Almadinah Almonawara, 42351 ...
Gomha SM, Abdelhady HA, Hassain DZH, Abdelmonsef AH, El-Naggar M, Elaasser MM, Mahmoud HK   +6 more
doaj  

SiO2@Benzothiazole‐Cl@Fc as an Efficient Heterogeneous Catalyst for the Synthesis of 1,3,5‐Trisubstituted Pyrazoles by A3 Coupling

ChemistryOpen, EarlyView.
This research introduces the preparation and analysis of a newly heterogeneous catalyst developed silica nanospheres supporting a ferrocene‐containing ionic liquid (SiO2@Benzothiazole‐Cl@Fc) for the A3 coupling reaction. The catalyst facilitates the efficient synthesis of 1,3,5‐trisubstituted pyrazoles from aromatic hydrazides, aldehydes, and aromatic ...
Fadhil Faez Sead, Vicky Jain, Roopashree R, Aditya Kashyap, Suman Saini, Girish Chandra Sharma, Pushpa Negi Bhakuni, Mosstafa Kazemi, Ramin Javahershenas   +8 more
wiley   +1 more source