Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H37Rv and the β-Ketoacyl-ACP Synthase mtFabH [PDF]
, 2009 Background Tuberculosis (TB) is a disease which kills two million people every year and infects approximately over one-third of the world's population.
Abbott, G +13 more
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Synthesis and Biological Evaluation of Bisthiazoles and Polythiazoles
Molecules, 2018 Small heterocyclic compounds containing nitrogen and sulfur atoms, such as thiazole derivatives, represent a significant class of organic azoles that exhibit promising bioactivities and have a great potential in medicinal and agricultural fields.
Mohammed A. Al-Omair +2 more
doaj +1 more source
Thiazole formation through a modified Gewald reaction
Beilstein Journal of Organic Chemistry, 2015 The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2 ...
Carl J. Mallia +3 more
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The thiazole and triazole derivatives as inhibitors of metal corrosion: Part II
Zaštita Materijala, 2016 The result of the literature survey about the possibility inhibition of copper corrosion in different conditions using thiazole and triazole derivatives are presented in this review.
Đenđi Vaštag, Jelena Nakomčić
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Scientific Opinion on the safety and efficacy of thiazoles, thiophene, thiazoline and thienyl derivatives (chemical group 29): 3-acetyl-2,5-dimethylthiophene when used as a flavouring for all animal species [PDF]
EFSA Journal, 2013 The current opinion concerns only one of the compounds belonging to chemical group 29, 3-acetyl-2,5-dimethylthiophene. 3-Acetyl-2,5-dimethylthiophene is genotoxic in vitro and in vivo.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
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Crystal structure of 4-(benzofuran-2-yl)-2-(3-(4-fluorophenyl)-3,3a,4,5-tetrahydro-2H-benzo[g]indazol-2-yl)thiazole, C28H20FN3OS [PDF]
, 2016 C28H20FN3OS, triclinic, P1̅ (no. 2), a = 9.5719(5) Å, b = 10.7499(6) Å, c = 10.9238(5) Å, α = 95.470(4)°, β = 102.133(4)°, γ = 97.962(4)°, V = 1079.30(10) Å3, R gt(F) = 0.0482, wR ref(F 2) = 0 ...
Abdel-Wahab, Bakr F. +4 more
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Iridium-Catalyzed Silylation of Five-Membered Heteroarenes: High Sterically Derived Selectivity from a Pyridyl-Imidazoline Ligand. [PDF]
, 2020 The steric effects of substituents on five-membered rings are less pronounced than those on six-membered rings because of the difference in bond angles. Thus, the regioselectivities of reactions of five-membered heteroarenes that occur with selectivities
Hartwig, John F +3 more
core +1 more source
sp3–sp3 carbon–carbon bonds formation using 2-alkylazoles and a bromoacrylate as the reaction partners [PDF]
, 2015 International ...
Bruneau, Christian +4 more
core +3 more sources
EFSA Journal, 2023 The Panel on Food Additives and Flavourings (FAF) was requested to consider the JECFA evaluations of 28 flavouring substances in the Flavouring Group Evaluation 76 (FGE.76Rev2). Twenty‐one of these substances have been considered in FGE.76Rev1.
EFSA Panel on Food Additives and Flavourings (FAF) +26 more
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Molecules, 2020 Thiazole derivatives attract the attention of scientists both in the field of organic synthesis and bioactivity research due to their high biological activity.
Birutė Sapijanskaitė-Banevič +4 more
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