Results 41 to 50 of about 44,050 (359)

Safety and efficacy of thiazoles, thiophene and thiazoline belonging to chemical group 29 when used as flavourings for all animal species

open access: yesEFSA Journal, 2016
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 12 compounds belonging to chemical group 29 ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Thiazole-Bearing 4-Thiazolidinones as New Anticonvulsant Agents

open access: yesScientia Pharmaceutica, 2020
Here, we describe the synthesis and anticonvulsant activity of thiazole-bearing hybrids based on 2-imino-4-thiazolidinone and 2,4-dioxothiazolidine-5-carboxylic acid cores.
Mariia Mishchenko   +3 more
doaj   +1 more source

Thiazoles in glycosylation reactions: Novel synthesis of thiazole thioglycosides

open access: yesHeteroatom Chemistry, 2017
AbstractThis research reports a novel method for synthesizing new thiazole thioglycosides. This series of thiazole thioglycosides were designed by the reaction of potassium cyanocarbonimidodithioate 2 with benzoyl acetonitrile 3a and ethyl bromoacetate 3b in the presence of ethanol‐KOH to give the corresponding potassium 4‐amino‐5‐substituted‐thiazole ...
Mamdouh A. Abu‐Zaied   +1 more
openaire   +2 more sources

Inhibition of Carboxylase by Thiazole Pyrophosphate [PDF]

open access: yesProceedings of the National Academy of Sciences, 1940
In the course of investigations dealing with vitamin B1 (thiamin) analogs, and having as their goal the furtherance of our knowledge of the physiological role of the vitamin, we have observed that a number of substances having a structure similar to that of cocarboxylase (thiamin pyrophosphate [1]), although not themselves able to replace the latter in
Buchman, Edwin R.   +2 more
openaire   +4 more sources

The thiazole and triazole derivatives as inhibitors of metal corrosion: Part II

open access: yesZaštita Materijala, 2016
The result of the literature survey about the possibility inhibition of copper corrosion in different conditions using thiazole and triazole derivatives are presented in this review.
Đenđi Vaštag, Jelena Nakomčić
doaj   +1 more source

Selected 5-amino-1-aryl-1H-1,2,3-triazole scaffolds as promising antiproliferative agents [PDF]

open access: yesThe Ukrainian Biochemical Journal, 2020
Development of a new effective drugs with low side effects and definite chemical characteristics needs indentification of bioactive scaffolds for further structural optimization.
N. Pokhodylo   +3 more
doaj   +1 more source

Thiazoles and Thiazolidinones as COX/LOX Inhibitors

open access: yesMolecules, 2018
Inflammation is a natural process that is connected to various conditions and disorders such as arthritis, psoriasis, cancer, infections, asthma, etc. Based on the fact that cyclooxygenase isoenzymes (COX-1, COX-2) are responsible for the production of ...
K. Liaras, M. Fesatidou, A. Geronikaki
semanticscholar   +1 more source

Application of Docking Analysis in the Prediction and Biological Evaluation of the Lipoxygenase Inhibitory Action of Thiazolyl Derivatives of Mycophenolic Acid

open access: yesMolecules, 2018
5-LOX inhibition is among the desired characteristics of anti-inflammatory drugs, while 15-LOX has also been considered as a drug target. Similarity in inhibition behavior between soybean LOX-1 and human 5-LOX has been observed and soybean LOX (sLOX ...
Evangelia Tsolaki   +4 more
doaj   +1 more source

A Convenient Ultrasound-Promoted Synthesis of Some New Thiazole Derivatives Bearing a Coumarin Nucleus and Their Cytotoxic Activity

open access: yesMolecules, 2012
Successful implementation of ultrasound irradiation for the rapid synthesis of a novel series of 3-[1-(4-substituted-5-(aryldiazenyl)thiazol-2-yl)hydrazono)ethyl]-2<em>H</em>-chromen-2-ones<strong> 5a</strong>–<strong>h< ...
Sobhi M. Gomha, Khaled D. Khalil
doaj   +1 more source

5-(4-Methoxyphenyl)-1-[4-(4-methoxyphenyl)thiazol-2-yl]-3-[4-(prop-2-ynyloxy)phenyl]-4,5-dihydro-1H-pyrazole

open access: yesIUCrData, 2022
The title compound, C29H25N3O3S, crystallizes in the monoclinic space group P21/n. The molecule contains a central four-ring system in which all of the rings are almost coplanar.
Sreeramapura D. Archana   +5 more
doaj   +1 more source

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