Results 131 to 140 of about 169,438 (276)
Experimental Physiology, EarlyView.Abstract Type 2 diabetes mellitus (T2DM) is associated with chronic systemic and cardiac inflammation, contributing to the development of diabetic cardiomyopathy. The mitochondrial‐derived peptide mitochondrial open reading frame of the 12S rRNA type‐C (MOTS‐c) has emerged as a promising regulator of metabolic and inflammatory pathways.
Aimee R. Mills +3 more
wiley +1 more source
Melatonin Protects Mouse Type A Spermatogonial Stem Cells against Oxidative Stress via The Mitochondrial Thioredoxin System. [PDF]
Cell J, 2023 Heidarizadi S +6 more
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley +1 more source
The dynamics of thioredoxin-dependent reactions. [PDF]
, 2014 M. Sc. University of KwaZulu-Natal, Pietermaritzburg 2014.The thioredoxin system, comprising thioredoxin (Trx), thioredoxin reductase (TrxR) and NADPH, is present in most organisms from prokaryotes to eukaryotes.
Photolo, Mampolelo M.
core
Regulation of the Thioredoxin System under Hypoxia and Different Oxygen Conditions
, 2011 The thioredoxin system is one of the key antioxidant systems in the cell and is crucial for cell survival. It is comprised of thioredoxin and thioredoxin reductase and plays important roles in maintaining the redox homeostasis within the cell.
Karlenius, Therese Christina
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray +16 more
wiley +1 more source
The thioredoxin system: Balancing redox responses in immune cells and tumors. [PDF]
Eur J Immunol, 2023 Muri J, Kopf M.
europepmc +1 more source
NADPH-Dependent Thioredoxin System In Regulation of Chloroplast Functions [PDF]
, 2011 Photosynthesis, the process in which carbon dioxide is converted into sugars using the energy of sunlight, is vital for heterotrophic life on Earth. In plants, photosynthesis takes place in specific organelles called chloroplasts.
Lepistö, Anna
core
The Journal of Physiology, EarlyView.Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto +7 more
wiley +1 more source
Cyclic Dichalcogenides Extend the Reach of Bioreductive Prodrugs to Harness Thiol/Disulfide Oxidoreductases: Applications to seco-Duocarmycins Targeting the Thioredoxin System. [PDF]
ACS Cent Sci, 2023 Felber JG +6 more
europepmc +1 more source