Trigonal-bipyramidal vs. octahedral coordination in indium(III) complexes with potentially S,N,S‐tridentate thiosemicarbazones [PDF]
, 2020 Three bis‐chelates of indium(III) with (partially fluorinated) S,N,S‐tridentate thiosemicarbazones (H2L) were prepared and their structures were studied in solution and in the solid state by NMR, ESI MS and single‐crystal X‐ray diffraction.
Abram, Ulrich +3 more
core +1 more source
Biomolecules, 2022 In this paper, thiosemicarbazide derivatives were synthesized as potential anticancer agents. X-ray investigations for 1-(2,4-dichlorophenoxy)acetyl-4-(2-fluorophenyl) thiosemicarbazide, 1-(2,4-dichlorophenoxy)acetyl-4-(4-metylothiophenyl ...
Paweł Kozyra +9 more
doaj +1 more source
A facile synthesis of N-Z/Boc-protected 1,3,4-oxadiazole-based peptidomimetics employing peptidyl thiosemicarbazides [PDF]
, 2010 Synthesis of 1,3,4-oxadiazole containing peptidomimetics is described by a p-TsCl/pyridine-mediated cyclization of the corresponding dipeptidyl thiosemicarbazides, which are readily prepared by coupling N-protected amino acid hydrazides with amino acid ...
Lamani, R.S. +2 more
core +1 more source
Molecules, 2022 The emergence of drug-resistant bacterial strains continues to be one of the major challenges of medicine. For this reason, the importance of searching for novel structures of antibacterial drugs chemically different from the currently known antibiotics ...
Sara Janowska +3 more
doaj +1 more source
Cytotoxic effect and molecular docking of 4-ethoxycarbonylmethyl-1-(piperidin-4-ylcarbonyl)-thiosemicarbazide—a novel topoisomerase II inhibitor [PDF]
, 2012 The preliminary cytotoxic effect of 4-ethoxycarbonylmethyl-1-(piperidin-4-ylcarbonyl)-thiosemicarbazide hydrochloride (1)—a potent topoisomerase II inhibitor—was measured using a MTT assay.
Agata Siwek +5 more
core +1 more source
Isatin thiosemicarbazone-blended polymer films for biomedical applications : surface morphology, characterisation and preliminary biological assessment [PDF]
, 2016 Poly (methyl methacrylate) and polyurethane are polymers currently used for a range of biomedical applications. To modify their surface characteristics, biocompatibility and potentially reduce any related side effects the addition to the polymers of ...
Alexiou, Polyxeni +5 more
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Synthesis, Reactions and Antimicrobial Activities of 8-Ethoxycoumarin Derivatives
Molecules, 2012 Condensation of 3-acetyl-8-ethoxycoumarin (3) with thiosemicarbazide gave ethylidenehydrazinecarbothioamide 5, which was transformed into the thiazolidin-4-one derivatives 6,7. Interaction of 3 with DMF/POCl3 gave b-chloroacroline derivative 8. Treatment
Mostafa M. Khafagy +6 more
doaj +1 more source
Journal of Pharmacopuncture, 2021 Objectives: Pathogenic microbes are causal agents for various types of severe and even lethal infectious diseases. Despite of development in medication, bacterial and fungal infections still persist to be a vital problem in health care.
Sagar Sahu +3 more
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Synthesis and Anthelmintic Activity of New Thiosemicarbazide Derivatives—A Preliminary Study
Molecules, 2020 Parasitic infections caused by different species of intestinal helminths still poses a threat to public health. There is a need to search for new, effective anthelmintic drugs. A series of novel thiosemicarbazides were synthesized and evaluated for their
Katarzyna Dziduch +4 more
doaj +1 more source
Investigation on Quantitative Structure-Activity Relationships of 1,3,4 Oxadiazole Derivatives as Potential Telomerase Inhibitors [PDF]
, 2018 The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/164022/article, DOI : 10.2174/1570163815666180724113208. © 2018 Bentham ScienceA series of 1,3,4-oxadiazole derivatives with significant broad-spectrum anticancer ...
Almerico, Anna Maria +2 more
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