Results 51 to 60 of about 8,698 (205)

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

2-(2-Imino-1-methylimidazolidin-4-ylidene)hydrazinecarbothioamide

Molbank, 2012
A new thiosemicarbazone, 1-methyl-2-imino-N-(methanethialdiamine)-yl-4-iminoimidazolidin was synthesized and its UV-VIS, IR, and NMR spectroscopic data and CHN analysis are presented.
Abdul Amir H. Kadhum, Abu Bakar Mohamad, Ahmed A. Al-Amiery   +2 more
doaj   +1 more source

Microwave‐Assisted Organic Syntheses in Deep Eutectic Solvents: A Win‐Win Association for Sustainable Chemistry

ChemistryOpen, EarlyView.
In organic synthesis, deep eutectic solvents (DES) have demonstrated their ability to be used as reaction media for the development of reactions in line with green chemistry principles. This review presents an overview of microwave‐assisted organic synthesis in DES, highlighting the diversity of uses for these solvents, their role in mechanisms, the ...
Pierre‐Olivier Delaye, Chefikou Salami, Emilie Thiery   +2 more
wiley   +1 more source

Synthesis and Antimicrobial Activity of Some New 1,3,4-Thiadiazole and 1,2,4-Triazole Compounds Having a D,L-Methionine Moiety

Molecules, 2007
New 1,3,4-thiadiazole, 5a-e, and 1,2,4-triazolecompounds 6a-c, containing a D,L-methionine moiety were synthesized by intramolecular cyclization of 1,4-disubstituted thiosemicarbazides 4a-e in acid and alkaline media, respectively.
Aurel Pui, Marcel Popa, Valeriu Sunel, Lenuta Profire, Otilia Pintilie   +4 more
doaj   +1 more source

Structure‐Guided Optimization and Biological Validation of 1,3,4‐Thiadiazole‐Based SIRT2 Inhibitors Reinforcing Channel Entrance Interactions

Drug Development Research, Volume 87, Issue 2, April 2026.
ABSTRACT SIRT2, the cytoplasmic member of the sirtuin family, is generally acknowledged to promote cancer and contribute to the progression of various pathologies, including neurodegeneration, inflammation, obesity, and bacterial infection through the deacetylation of target substrates.
Ahmet Bugra Aksel, Fikriye Ozgencil, Filiz Bakar‐Ates, Habibe Beyza Gunindi, Alberto Massarotti, Erva Ozkan, Selen Gozde Kaya, Mahmut Gozelle, Yesim Ozkan, Gokcen Eren   +9 more
wiley   +1 more source

Biocompatibility of a self-assembled crosslinkable hyaluronic acid nanogel [PDF]

, 2016
Hyaluronic acid nanogel (HyA-AT) is a redox sensitive crosslinkable nanogel, obtained through the conjugation of a thiolated hydrophobic molecule to the hyaluronic acid chain.
Correia, Alexandra, Gama, F. M., Moreira, Susana, Pedrosa, Sílvia Santos, Pereira, Paula Alexandra Cunha, Rocha, Huho   +5 more
core   +2 more sources

Study of the Relationships between the Structure, Lipophilicity and Biological Activity of Some Thiazolyl-carbonyl-thiosemicarbazides and Thiazolyl-azoles

Molecules, 2015
Lipophilicity, as one of the most important physicochemical parameters of bioactive molecules, was investigated for twenty-two thiazolyl-carbonyl-thiosemicarbazides and thiazolyl-azoles.
Radu Tamaian, Augustin Moţ, Radu Silaghi-Dumitrescu, Ioana Ionuţ, Anca Stana, Ovidiu Oniga, Cristina Nastasă, Daniela Benedec, Brînduşa Tiperciuc   +8 more
doaj   +1 more source

Does thiosemicarbazide lead nitrate crystal exist? [PDF]

Optik, 2016
3 ...
Fernandes, R., Srinivasan, Bikshandarkoil R.   +1 more
openaire   +2 more sources

Dietary essential oils modulate post‐mortem oxidative damage in trout fillets exposed to slaughter stress during frozen storage

Journal of the Science of Food and Agriculture, Volume 106, Issue 6, Page 3686-3695, April 2026.
Abstract BACKGROUND Slaughter is a critical phase in aquaculture that can severely compromise both animal welfare and product quality. Stress responses triggered during this stage may accelerate post‐mortem biochemical degradation and promote oxidative damage in fish fillets. Essential oils, known for their antioxidant and anti‐inflammatory properties,
Lucía Méndez, Giulia Secci, Lorena Barros, Gabriel Dasilva, Giuliana Parisi, Isabel Medina   +5 more
wiley   +1 more source

2-Methyl-3-thiosemicarbazide

Acta Crystallographica Section E Structure Reports Online, 2007
The title compound, C2H7N3S, exhibits an anti arrangement between the thione S atom and the hydrazine N atom. The thio­semicarbazide mol­ecules are inter­connected into a three-dimensional hydrogen-bonded network.
Jesús Valdés-Martínez, Rubén A. Toscano   +1 more
openaire   +1 more source