Results 61 to 70 of about 8,698 (205)

1-[2-(4-Isobutylphenyl)propanoyl]thiosemicarbazide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
في مركب العنوان، C(14)H(21)N(3)OS، تولد التفاعلات بين الجزيئات N - H - O حلقات ذات عشرة أطراف بزخارف حلقية R(2)(2) (10)، بينما تولد تفاعلات N - H - S ثماني حلقات و 14 و 16 عضوًا بزخارف حلقية R(2)(2) (8) و R (4)(4) (14) و R(4)(4)(16)، على التوالي. هناك تفاعلات ضعيفة داخل الجزيء N - H π والتي قد تؤثر على تكوّن الجنين.
Hoong‐Kun Fun, Reza Kia, S.R. Jebas, K. V. Sujith, Balakrishna Kalluraya   +4 more
openaire   +3 more sources

From Design to Bioactivity: 2‐Benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone and Its 3d Metal Coordination Compounds

ChemistryOpen, Volume 15, Issue 4, April 2026.
The new 2‐benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone (HL) and its copper(II), nickel(II), cobalt(III), and iron(III) coordination compounds [Cu(L)Cl] (1), [Cu(L)NO3] (2), {[Cu(L)(Cl2CHCOO)]}n (3), [Ni(HL)2](NO3)2 (4), [Fe(L)2]NO3 (5), [Co(L)2]NO3 (6) were obtained.
Ianina Graur, Vasilii Graur, Elena Melnic, Carolina Lozan‐Tirsu, Greta Balan, Victor Tsapkov, Aurelian Gulea   +6 more
wiley   +1 more source

Exploring Novel Nitrofuryl‐1,3,4‐Thiadiazole‐Based Derivatives: Design, Synthesis, and Evaluation of In Vitro Leishmanicidal and Trypanocidal Activity

Archiv der Pharmazie, Volume 359, Issue 3, March 2026.
In a series of substituted 1‐[5‐(5‐nitrofuran‐2‐yl)‐1,3,4‐thiadiazol‐2‐yl]piperidine‐4‐carboxamides evaluated for in vitro antileishmanial and antitrypanosomal activity, compound 18 emerged as the most promising derivative, showing submicromolar anti‐parasitic effects targeting diverse Leishmania and Trypanosoma species and acceptable selectivity ...
Alireza Mousavi, Martina Slapničková, Maryam Norouzbahari, Sarah D'Alessandro, Parham Foroumadi, Fariba Peytam, Federica Perego, Eva Doleželová, Zahra Emamgholipour, Maliheh Barazandeh Tehrani, Seyed Esmaeil Sadat‐Ebrahimi, Elahe Hosseinzadeh, Elmira Meghrazi Ahadi, Loghman Firoozpour, Hamidreza Bijanzadeh, Nicoletta Basilico, Alena Zíková, Alireza Foroumadi   +17 more
wiley   +1 more source

Microwave-Assisted Synthesis of New N1,N4-Substituted Thiosemicarbazones

Molecules, 2011
We present an efficient procedure for the synthesis of thirty-six N1,N4-substituted thiosemicarbazones, including twenty-five ones that are reported for the first time, using a microwave-assisted methodology for the reaction of thiosemicarbazide ...
Aurea Echevarria, Danilo Sousa Pereira, Lucimar Ferreira Kneipp, Rojane de Oliveira Paiva, Camilla Moretto dos Reis   +4 more
doaj   +1 more source

Imidazole-Thiosemicarbazide Derivatives as Potent Anti-Mycobacterium tuberculosis Compounds with Antibiofilm Activity

Cells, 2021
Mycobacterium tuberculosis (Mtb) is an intracellular pathogenic bacterium and the causative agent of tuberculosis. This disease is one of the most ancient and deadliest bacterial infections, as it poses major health, social and economic challenges at a ...
Adrian Bekier, Malwina Kawka, Jakub Lach, Jarosław Dziadek, Agata Paneth, Justyna Gatkowska, Katarzyna Dzitko, Bożena Dziadek   +7 more
doaj   +1 more source

4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis [PDF]

, 2019
A new series of 4-(3-nitrophenyl)thiazol-2-ylhydrazone derivatives were designed, synthesised, and evaluated to assess their inhibitory effect on the human monoamine oxidase (hMAO) A and B isoforms. Different (un)substituted (hetero)aromatic substituents
Alcaro, Stefano, Bagetta, Donatella, Carradori, Simone, Chimenti, Paola, D’Ascenzio, Melissa, Guglielmi, Paolo, Ortuso, Francesco, Petzer, Anél, Petzer, Jacobus P., Secci, Daniela, Zengin, Gokhan   +10 more
core   +1 more source

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, Volume 73, Issue 1, Page 14-27, February 2026.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

Four cytotoxic N4-substituted thiosemicarbazones derived from 2-hydroxynaphthalene-1-carboxaldehyde [PDF]

, 2003
The X-ray crystal structures are reported of four novel and potentially O,N,S-tridentate donor ligands that demonstrate antitumour activity.
Bernhardt, P. V., Caldwell, L., Lovejoy, D., Richardson, D. R.   +3 more
core   +1 more source

Reprogramming Immunogenicity of Iron Oxide Nanoparticles through Sulfated Glycan Presentation

Small, Volume 22, Issue 11, 20 February 2026.
This study presents a comparative analysis of heparin (HP)‐ and dextran sulfate (DS)‐coated superparamagnetic iron oxide nanoparticles (SPIONs) as a tunable immunomodulatory platform where surface chemistry dictates therapeutic function. DS‐SPIONs are preferentially internalized by myeloid cells, reprogramming them into a pro‐healing M2 phenotype ...
Negin Pournoori, Heela Sarlus, Dick J. Sjöström, Rohith Pavan Parvathaneni, Oommen P. Varghese, Vesa P. Hytönen, Robert A. Harris, Per H. Nilsson, Oommen P. Oommen   +8 more
wiley   +1 more source

Synthetical Application of Alkyl 2-isothiocyanatocarboxylates. A Simple Synthesis of 5-Substituted-3-amino-2-thioxo-4-imidazolidinones (3-Amino-2-thiohydantoins)

Molecules, 1999
The title 3-amino-2-thiohydantoins 3 has been prepared in very good yields by the reaction of alkyl isothiocynatocarboxylates 1 with hydrazine hydrate.The synthesis of starting isothiocyanates as well as spectral data of 3-aminothiohydantoins and alkyl ...
Martin Kovac, Vladimir Oremus, Lubomir Floch   +2 more
doaj   +1 more source