Results 41 to 50 of about 1,856 (207)
Third-generation sequencing and the future of genomics [PDF]
, 2016 Abstract Third-generation long-range DNA sequencing and mapping technologies are creating a renaissance in high-quality genome sequencing. Unlike second-generation sequencing, which produces short reads a few hundred base-pairs long, third-generation single-molecule technologies generate over 10,000 bp reads or map ...
Lee, Hayan +7 more
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Rapid diagnosis of Mycobacterium marinum infection using targeted nanopore sequencing: a case report
Frontiers in Cellular and Infection Microbiology, 2023 Mycobacterium marinum (M. marinum) is a non-tuberculous mycobacterium (NTM) that can cause infectious diseases in aquatic animals and humans. Culture-based pathogen detection is the gold standard for diagnosing NTM infection. However, this method is time-
Yan-Ying Huang +4 more
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A Sequence-Based Novel Approach for Quality Evaluation of Third-Generation Sequencing Reads [PDF]
Genes, 2019 The advent of third-generation sequencing (TGS) technologies, such as the Pacific Biosciences (PacBio) and Oxford Nanopore machines, provides new possibilities for contig assembly, scaffolding, and high-performance computing in bioinformatics due to its long reads.
Zhang, Wenjing +5 more
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Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline
Agriculture, 2018 With the global human population growing rapidly, agricultural production must increase to meet crop demand. Improving crops through breeding is a sustainable approach to increase yield and yield stability without intensifying the use of fertilisers and ...
Haifei Hu, Armin Scheben, David Edwards
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DNA Preparation In Vitis Vinifera L. for Third Generation Sequencing [PDF]
, 2021 Abstract Background: There have been several attempts to sequence the genome of Vitis vinifera L. (grapevine), utilizing low-resolution second-generation platforms. Nevertheless, the characterization of the grapevine genetic resources and its adaptation to vulnerable conditions could be better addressed through extensive and high-resolution ...
Bibi C. Androniki +6 more
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Life, 2022 Next-generation sequencing (NGS) applications have flourished in the last decade, permitting the identification of cancer driver genes and profoundly expanding the possibilities of genomic studies of cancer, including melanoma. Here we aimed to present a
Adrián Muñoz-Barrera +7 more
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Emerging Microbes and Infections, 2023 Virus circular RNAs (circRNA) have been reported to be extensively expressed and play important roles in viral infections. Previously we build the first database of virus circRNAs named VirusCircBase which has been widely used in the field.
Ping Fu +4 more
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BMC Genomics, 2020 Background The emergence of the third generation sequencing technology, featuring longer read lengths, has demonstrated great advancement compared to the next generation sequencing technology and greatly promoted the biological research.
Jiaqi Liu +9 more
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Analyzing Modern Biomolecules: The Revolution of Nucleic-Acid Sequencing – Review
Biomolecules, 2021 Recent developments have revolutionized the study of biomolecules. Among them are molecular markers, amplification and sequencing of nucleic acids. The latter is classified into three generations. The first allows to sequence small DNA fragments.
Gabriel Dorado +4 more
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Evolutionary Insight into the Trypanosomatidae Using Alignment-Free Phylogenomics of the Kinetoplast
Pathogens, 2019 Advancements in next-generation sequencing techniques have led to a substantial increase in the genomic information available for analyses in evolutionary biology.
Alexa Kaufer, Damien Stark, John Ellis
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