Results 31 to 40 of about 1,856 (207)
Identification of double heterozygous -α4.2Ⅰ/-α4.2Ⅱ using third-generation sequencing
Hematology, 2023 Objective The 4.2 kb deletion (-α4.2/) is a common a+-thalassemia with a carrier rate, followed by the South-East Asian deletion (–SEA) and the 3.7 kb deletion (-α3.7/). There are few reports about 4.2 kb deletion sub-types.
Liang Liang +5 more
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Computational methods for 16S metabarcoding studies using Nanopore sequencing data
Computational and Structural Biotechnology Journal, 2020 Assessment of bacterial diversity through sequencing of 16S ribosomal RNA (16S rRNA) genes has been an approach widely used in environmental microbiology, particularly since the advent of high-throughput sequencing technologies.
Andres Santos +3 more
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Data in Brief, 2020 The complete genome of the thraustochytrid Aurantiochytrium limacinum strain CCAP_4062/1 was sequenced using both Illumina Novaseq 6000 and third generation sequencing technology PacBio RSII in order to obtain trustworthy assembly and annotation.
Christian Morabito +4 more
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Cheap third-generation sequencing [PDF]
Nature Methods, 2009 By covalently attaching cyclodextrin to a hemolysin nanopore, researchers show single-molecule, label-free sequencing at very high accuracy.
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PaSS: a sequencing simulator for PacBio sequencing
BMC Bioinformatics, 2019 Background Third-generation sequencing platforms, such as PacBio sequencing, have been developed rapidly in recent years. PacBio sequencing generates much longer reads than the second-generation sequencing (or the next generation sequencing, NGS ...
Wenmin Zhang, Ben Jia, Chaochun Wei
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The third generation sequencing: the advanced approach to genetic diseases
Translational Pediatrics, 2020 Genomic sequencing technologies have revolutionized mutation detection of the genetic diseases in the past few years. In recent years, the third generation sequencing (TGS) has been gaining insight into more genetic diseases owing to the single molecular and real time sequencing technology.
Xiao, Tiantian, Zhou, Wenhao
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Highly Contiguous Genome Assemblies of 15 Drosophila Species Generated Using Nanopore Sequencing
G3: Genes, Genomes, Genetics, 2018 The Drosophila genus is a unique group containing a wide range of species that occupy diverse ecosystems. In addition to the most widely studied species, Drosophila melanogaster, many other members in this genus also possess a well-developed set of ...
Danny E. Miller +3 more
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Third-Generation Sequencing in the Clinical Laboratory: Exploring the Advantages and Challenges of Nanopore Sequencing [PDF]
Journal of Clinical Microbiology, 2019 Metagenomic sequencing for infectious disease diagnostics is an important tool that holds promise for use in the clinical laboratory. Challenges for implementation so far include high cost, the length of time to results, and the need for technical and bioinformatics expertise.
Lauren M, Petersen +4 more
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Frontiers in Oncology, 2023 The link between viruses and cancer has intrigued scientists for decades. Certain viruses have been shown to be vital in the development of various cancers by integrating viral DNA into the host genome and activating viral oncogenes.
Ruichen Ye +9 more
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Challenges in Third-Generation DNA Sequencing [PDF]
Journal of Nanomedicine & Nanotechnology, 2012 DNA sequencing is one of the leading precursors of the personalized medicine, i.e. for reading hereditary traits for predisposition to diseases which are coded in DNA, and thus to prevent, diagnose, and treat diseases. After the success of the Human Genome Project in 2003, which achieved reading a human genome for $3B spent over thirteen years, the ...
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