Results 31 to 40 of about 6,398,546 (257)

Benchmarking second and third-generation sequencing platforms for microbial metagenomics

Scientific Data, 2022
Measurement(s) mock community • Metagenomic profiling Technology Type(s) Illumina HiSeq 3000 • ThermoFisher Ion Proton and GeneStudio S5 • MGI DNBseq G400 and T7 • Oxford Nanopore Sequencing • PacBio Sequel System • Genome mapping and assembly Sample ...
Victoria Meslier, Benoit Quinquis, Kévin Da Silva, Florian Plaza Oñate, Nicolas Pons, Hugo Roume, Mircea Podar, Mathieu Almeida   +7 more
doaj   +1 more source

Diagnostic applications of next generation sequencing: working towards quality standards [PDF]

, 2012
Over the past 6 years, next generation sequencing (NGS) has been established as a valuable high-throughput method for research in molecular genetics and has successfully been employed in the identification of rare and common genetic variations. All major
Klein, Hanns-Georg, Biskup, S., Vogl, Ina, Hirv, K., Greif, P.A., Kotschote, S., Gehring, A., Kuhn, M., Stuhrmann, Manfred, Bergmann, C., Eck, Sebastian H., Biskup, Saskia, Metzeler, Klaus H., Greif, Philipp A., Stuhrmann, M., Bolz, Hanno Joern, Benet-Pages, Anna, Hirv, Kaimo, Benet-Pagès, A., Klein, H.G., Vogl, I., Bolz, H.J., Kuhn, Marius, Kotschote, Stefan, Gehring, Andrea, Bergmann, Carsten, Metzeler, K.H., Eck, S.H.   +27 more
core   +1 more source

3GOLD: optimized Levenshtein distance for clustering third-generation sequencing data

BMC Bioinformatics, 2022
Background Third-generation sequencing offers some advantages over next-generation sequencing predecessors, but with the caveat of harboring a much higher error rate. Clustering-related sequences is an essential task in modern biology.
Robert Logan, Zoe Fleischmann, Sofia Annis, Amy Wangsness Wehe, Jonathan L. Tilly, Dori C. Woods, Konstantin Khrapko   +6 more
doaj   +1 more source

RADSeq: next-generation population genetics [PDF]

, 2010
Next-generation sequencing technologies are making a substantial impact on many areas of biology, including the analysis of genetic diversity in populations.
Davey, John L, M. L. Blaxter, Blaxter, Mark W, J. W. Davey   +3 more
core   +1 more source

Highly Contiguous Genome Assemblies of 15 Drosophila Species Generated Using Nanopore Sequencing

G3: Genes, Genomes, Genetics, 2018
The Drosophila genus is a unique group containing a wide range of species that occupy diverse ecosystems. In addition to the most widely studied species, Drosophila melanogaster, many other members in this genus also possess a well-developed set of ...
Danny E. Miller, Cynthia Staber, Julia Zeitlinger, R. Scott Hawley   +3 more
doaj   +1 more source

Characterization of Third-Generation Cephalosporin-Resistant Escherichia coli Isolated from Pigs in Cuba Using Next-Generation Sequencing. [PDF]

, 2021
Resistance to third-generation cephalosporins (3GC) in Escherichia coli has been reported worldwide from humans and animals, but the situation in Cuba is still poorly understood.
Marrero-Moreno, Carelia Martha, Baez, Michel, Hernandez-Fillor, Rosa Elena, Espinosa, Ivette, Perreten, Vincent, Brilhante, Michael, Michel Baez, Vincent Perreten, Ivette Espinosa, Carelia Martha Marrero-Moreno, Michael Brilhante, Rosa Elena Hernández-Fillor   +11 more
core   +1 more source

Recovery of human gut microbiota genomes with third-generation sequencing

Cell Death and Disease, 2021
Human gut microbiota modulates normal physiological functions, such as maintenance of barrier homeostasis and modulation of metabolism, as well as various chronic diseases including type 2 diabetes and gastrointestinal cancer. Despite decades of research,
Yanfei Li, Yueling Jin, Jianming Zhang, Haoying Pan, Lan Wu, Dingsheng Liu, Jinlong Liu, Jing Hu, Junwei Shen   +8 more
doaj   +1 more source

Viral oncogenes, viruses, and cancer: a third-generation sequencing perspective on viral integration into the human genome

Frontiers in Oncology, 2023
The link between viruses and cancer has intrigued scientists for decades. Certain viruses have been shown to be vital in the development of various cancers by integrating viral DNA into the host genome and activating viral oncogenes.
Ruichen Ye, Ruichen Ye, Ruichen Ye, Angelina Wang, Brady Bu, Pengxiang Luo, Wenjun Deng, Xinyi Zhang, Shanye Yin, Shanye Yin   +9 more
doaj   +1 more source

High-throughput SuperSAGE for digital gene expression analysis of multiple samples using next generation sequencing [PDF]

, 2010
We established a protocol of the SuperSAGE technology combined with next-generation sequencing, coined "High- Throughput (HT-) SuperSAGE". SuperSAGE is a method of digital gene expression profiling that allows isolation of 26-bp tag fragments from ...
Schroth, G.P., Terauchi, Ryohei, Hideo Matsumura, Krüger Detlev H., Kentaro Yoshida, Kahl, G., Takahiro Fujibe, Luo, Shujun, Fujibe, T., Terauchi Ryohei, Eiji Kimura, Yoshida Kentaro, Luo, S., Shujun Luo, Barrero, R.A., Schroth, Gary P., Detlev H Krüger, Albertyn, Z., Ryohei Terauchi, Roberto A Barrero, Kahl Günter, Luo Shujun, Albertyn Zayed, Gary P. Schroth, Matsumura, Hideo, Yoshida, K., Fujibe, Takahiro, Schroth Gary P., Krüger, D.H., Kahl, Günter, Krüger, Detlev H., Kimura, Eiji, Gary P Schroth, Matsumura Hideo, Barrero Roberto A., Zayed Albertyn, Kimura, E., Terauchi, R., Kimura Eiji, Detlev H. Krüger, Albertyn, Zayed, Matsumura, H., Yoshida, Kentaro, Fujibe Takahiro, Barrero, Roberto A., Roberto A. Barrero, Günter Kahl, Kahl, Guenter, Schroth, Gary P, Krueger, Detlev H, Barrero, Roberto A   +50 more
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Advances in Integrating Genomics and Bioinformatics in the Plant Breeding Pipeline

Agriculture, 2018
With the global human population growing rapidly, agricultural production must increase to meet crop demand. Improving crops through breeding is a sustainable approach to increase yield and yield stability without intensifying the use of fertilisers and ...
Haifei Hu, Armin Scheben, David Edwards
doaj   +1 more source