Results 61 to 70 of about 4,457,527 (301)

Prognostic significance of short-term blood pressure variability in acute stroke [PDF]

, 2015
Background and Purpose— Blood pressure variability (BPV) may be an important prognostic factor acutely after stroke. This review investigated the existing evidence for the effect of BPV on outcome after stroke, also considering ...
Manning, Lisa S., Potter, John F., Robinson, Thompson G., Rothwell, Peter M.   +3 more
core   +1 more source

Thrombolytic therapy for pulmonary embolism.

Cochrane Database of Systematic Reviews, 2015
BACKGROUND Thrombolytic therapy (powerful anticoagulation drugs) is usually reserved for patients with clinically serious or massive pulmonary embolism (PE).
Q. Hao, B. Dong, J. Yue, Taixiang Wu, G. Liu   +4 more
semanticscholar   +1 more source

Safety of alteplase intravenous thrombolysis and influencing factors of clinical outcome in elderly patients with acute ischemic stroke

BMC Neurology
Objective To explore the safety of intravenous thrombolysis with alteplase (rt-PA) in the treatment of acute ischemic stroke (AIS) in the elderly (≥ 80 years old) and with analyze the influencing factors of its clinical outcome.
Yongyin Zhang, Lifen Chi, Hao Shu, Qiang Zhou, Shunkai Zhang, Xuerong Huang, Xiaoyi Song   +6 more
doaj   +1 more source

Analysis of the Navigation of Magnetic Microrobots through Cerebral Bifurcations for Targeted Drug Delivery

Advanced Intelligent Systems, EarlyView.
The motion of magnetic microrobots through cerebral bifurcations depends on various parameters such as the microrobots size, the blood velocity, and the imposed magnetic field gradients, among others. This work presents an in‐depth analysis of the effects of these parameters and equations predicting the required magnetic gradients based on the ...
Pedro G. Alves, Maria Pinto, Rosa Moreira, Derick Sivakumaran, Fabian Landers, Maria Guix, Bradley J. Nelson, Andreas D. Flouris, Salvador Pané, Josep Puigmartí‐Luis, Tiago S. Mayor   +10 more
wiley   +1 more source

Editor's choice : European Society for Vascular Surgery (ESVS) 2020 clinical practice guidelines on the management of acute limb ischaemia

, 2020
A
Acosta, Stefan, Azuma, Nobuyoshi, Bastos Gonçalves, Frederico, Björck, Martin, Boyle, Jonathan R., Chakfé, Nabil, Choke, Edward T. C., Cochennec, Frederic, Cohnert, Tina U., de Borst, Gert J., Document Reviewers, Earnshaw, Jonothan J., ESVS Guidelines Committee, Fitridge, Robert A., Forbes, Thomas L., Hamady, Mohamad S., Hinchliffe, Robert, Jongkind, Vincent, Kakkos, Stavros K., Koelemay, Mark J. W., Koncar, Igor, Lindholt, Jes S., Mani, Kevin, Menyhei, Gabor, Munoz, Alberto, Müller-Hülsbeck, Stefan, Rai, Kumud, Sebastian Debus, E., Svetlikov, Alexei V., Tshomba, Yamume, Tulamo, Riikka, van den Berg, Jos C., Vega de Ceniga, Melina, Vermassen, Frank   +33 more
core   +2 more sources

Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research. [PDF]

, 2017
Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size.
Akyol, Onat, Applegate, Richard, Araujo, Camila, Ho, Wing Mann, Huang, Lei, Reis, Cesar, Zhang, John H   +6 more
core   +3 more sources

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

A fibrin targeted molecular imaging evaluation of microvascular no‐reflow in acute ischemic stroke

Brain and Behavior, 2022
Objective To investigate the relationship between fibrin deposition and “no‐reflow” within microcirculation after thrombolysis in acute ischemic stroke (AIS).
Xi Chen, Jing Wang, Liang Ge, Gang Lu, Hailin Wan, Yeqing Jiang, Zhenwei Yao, Gang Deng, Xiaolong Zhang   +8 more
doaj   +1 more source

Chemical Components of the Dried Latex of Euphorbia resinifera Berg and Its Medicinal Features

Chemistry &Biodiversity, EarlyView.
ABSTRACT A great deal of research has been carried out on the latex of Euphorbia resinifera Berg, which is an important source of several compounds of therapeutic and medicinal interest. Extraction, synthesis, and hemi synthesis pathways continue to reveal the existence of other new products with anticancer, antioxidant, antidiuretic, and antimalarial ...
Doaa Hammad, El‐Mahdi Ourhzif, Salha Hamri, Hafid Abderrafia, Mostafa Khouili, Maria Dolors Pujol   +5 more
wiley   +1 more source

Thrombolysis in very elderly people: controlled comparison of SITS international stroke thrombolysis registry and virtual international stroke trials archive [PDF]

, 2010
<p>Objective To assess effect of age on response to alteplase in acute ischaemic stroke.</p> <p>Design Adjusted controlled comparison of outcomes between non-randomised patients who did or did not undergo thrombolysis.
Ahmed, N., Andersen, G., Egido, J.A., Lees, K.R., Lindsberg, P.J., Mishra, N.K., Ringleb, P.A., Wahlgren, N.G.   +7 more
core   +1 more source