Results 61 to 70 of about 1,985,368 (271)

Defining the elusive oncogenic role of the methyltransferase TMT1B

open access: yesFrontiers in Oncology, 2023
Methyltransferases are enzymes fundamental to a wide range of normal biological activities that can become dysregulated during oncogenesis. For instance, the recent description of the methyltransferase-like (METTL) family of enzymes, has demonstrated the
Sarah E. Denford   +2 more
doaj   +1 more source

Resolution- and throughput-enhanced spectroscopy using a high-throughput computational slit [PDF]

open access: yesOptics Letters, 2016
There exists a fundamental tradeoff between spectral resolution and the efficiency or throughput for all optical spectrometers. The primary factors affecting the spectral resolution and throughput of an optical spectrometer are the size of the entrance aperture and the optical power of the focusing element. Thus far collective optimization of the above
Alexander Wong, Farnoud Kazemzadeh
openaire   +4 more sources

Exploring the impact of primer length on efficient gene detection via high-throughput sequencing

open access: yesNature Communications
Reverse transcription (RT) is a crucial step in most RNA analysis methods. Optimizing protocols for this initial stage is critical for effective target detection, particularly when working with limited input RNA.
Julia Micheel   +3 more
doaj   +1 more source

A Programmable, Scalable-Throughput Interleaver [PDF]

open access: yesEURASIP Journal on Wireless Communications and Networking, 2010
The interleaver stages of digital communication standards show a surprisingly large variation in throughput, state sizes, and permutation functions. Furthermore, data rates for 4G standards such as LTE-Advanced will exceed typical baseband clock frequencies of handheld devices.
C. H. vanBerkel, E. J. C. Rijshouwer
openaire   +4 more sources

Meta-analysis of kindling-induced gene expression changes in the rat hippocampus

open access: yesFrontiers in Neuroscience, 2009
Numerous studies have been performed to examine gene expression patterns in the rodent hippocampus in the kindling model of epilepsy. However, recent reviews of this literature have revealed limited agreement among studies.
Sanja Rogic, Paul Pavlidis
doaj   +1 more source

HERB: a high-throughput experiment- and reference-guided database of traditional Chinese medicine

open access: yesNucleic Acids Res., 2020
Pharmacotranscriptomics has become a powerful approach for evaluating the therapeutic efficacy of drugs and discovering new drug targets. Recently, studies of traditional Chinese medicine (TCM) have increasingly turned to high-throughput transcriptomic ...
Shuangsang Fang   +14 more
semanticscholar   +1 more source

Approximations for Throughput Maximization

open access: yesAlgorithmica
In this paper we study the classical problem of throughput maximization. In this problem we have a collection $J$ of $n$ jobs, each having a release time $r_j$, deadline $d_j$, and processing time $p_j$. They have to be scheduled non-preemptively on $m$ identical parallel machines.
Hyatt-Denesik, Dylan   +2 more
openaire   +5 more sources

On the Throughput Cost of Physical Layer Security in Decentralized Wireless Networks

open access: yes, 2011
This paper studies the throughput of large-scale decentralized wireless networks with physical layer security constraints. In particular, we are interested in the question of how much throughput needs to be sacrificed for achieving a certain level of ...
Andrews, Jeffrey G.   +3 more
core   +1 more source

Utilising acoustic mist ionisation mass spectrometry to identify redox cycling compounds in high throughput screening outputs

open access: yesSLAS Discovery, 2022
Rapid triage of compounds acting via undesired mechanisms is a crucial stage in a high-throughput screening (HTS) cascade to ensure time and resource is efficiently assigned to the most propitious hits.
Rachel Moore   +4 more
doaj  

Glc7/PP1 dephosphorylates histone H3T11 to regulate autophagy and telomere silencing in response to nutrient availability

open access: yesCell Discovery, 2023
How cells adapt their gene expression to nutritional changes remains poorly understood. Histone H3T11 is phosphorylated by pyruvate kinase to repress gene transcription.
Xinyu Zhang   +7 more
doaj   +1 more source

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