Results 61 to 70 of about 2,741,553 (288)

Association between Sensitivity to Thyroid Hormone Indices and Bone Mineral Density in US Males

International Journal of Endocrinology, 2022
Objectives. Thyroid hormone is acknowledged as a pivotal factor in skeletal development and adult bone maintenance. However, available data about the relationship between sensitivity to thyroid hormone and bone mineral density (BMD) remain limited and ...
Shuai Chen, Wucui Huang, Guowei Zhou, Xiaohe Sun, Jie Jin, Zhiwei Li   +5 more
doaj   +1 more source

A Novel NR3C1 Frameshift Variant Associated With Familial Glucocorticoid Resistance Syndrome: An Integrated Analysis of Steroid Profiling and Structural Modeling

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Glucocorticoid resistance syndrome (GRS) is a rare hereditary disorder caused by pathogenic variants in NR3C1, characterized by marked phenotypic heterogeneity and frequent misdiagnosis as primary aldosteronism or subclinical Cushing's syndrome.
Sufang Yun, Zhifeng Zhu, Fengye Zhou, Ying Liu, Chunfang Liang, Haitao Ju, Lin Lu, Zhaoli Yan   +7 more
wiley   +1 more source

ADNP‐Related Helsmoortel–Van der Aa Syndrome: A Review of the Literature and Clinical Recommendations for Assessment and Monitoring

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman, Ana Kolevzon, Paige Siper, Tess Levy, Jeffrey M. Saland, Yitzchak Frank, Robert Rapaport, Kayla Kupietzky, William E. Bennett Jr, Bruce Gelb, Sandra Bedrosian Sermone, Alexander Kolevzon   +11 more
wiley   +1 more source

Syndromes of resistance to thyroid hormone

Клиническая и экспериментальная тиреоидология, 2013
Синдром резистентности к тиреоидным гормо нам (RTH) является наследственным синдромом, характеризующимся пониженной чувствительнос тью тканеймишеней к гормонам щитовидной желе зы.

doaj   +1 more source

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
Mohammed Elsalanty, Jack C Yu, Cray, JJ, Elsalanty, M, Yu Jack C., James J Cray, Weinberg, SM, Khaksarfard Kameron, Cray, James J., Yu, JC, Khaksarfard, K, Yu, Jack C., Elsalanty, Mohammed, Kameron Khaksarfard, Weinberg Seth M., Weinberg, Seth M., Cray James J., Khaksarfard, Kameron, Seth M Weinberg, Elsalanty Mohammed   +19 more
core   +2 more sources

Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri, Alessandro Serretti, Marco Menchetti, Benedetta Vai, Francesco Benedetti, Lidia Fortaner‐Uyà, Concetta Crisafulli   +6 more
wiley   +1 more source

Relationship of thyroid hormones and metabolic parameters in euthyroid women

Turkish Journal of Family Practice
Objective: Thyroid hormones play a role in metabolic regulation, yet their associations with obesity and insulin resistance in euthyroid individuals remain unclear. This study aimed to evaluate the relationship between thyroid-stimulating hormone (TSH),
Fatma Nur Yürekten Sıcakyüz, Furkan Alp Eren, Kağan Güngör, Hacer Hicran Mutlu   +3 more
doaj   +1 more source

Psychological well-being on thyroid hormone replacement [PDF]

Despite 100 years after the discovery of thyroxine, controversy still exists regarding optimal thyroid hormone replacement therapy. Several anecdotal reports suggest that thyroxine alone therapy does not normalise psychological wellbeing.
Saravanan, Ponnusamy
core  

Resistance to Thyroid Hormone (RTH)

, 2004
The syndrome of resistance to thyroid hormone (RTH) is characterized by reduced tissue responsiveness to thyroid hormone (TH) despite elevated circulating levels of free triiodothyronine (T3) and thyroxine (T4).
Roy E. Weiss, Gisah Amaral de Carvalho, de Carvalho, Gisah Amaral, Weiss, Roy E   +3 more
core   +1 more source

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source