Results 81 to 90 of about 2,741,553 (288)

Elevated total cholesterol in healthy adults mediates the association between impaired thyroid hormone sensitivity and hyperuricemia

Frontiers in Endocrinology
PurposeThis study aims to explore the association between impaired thyroid hormone sensitivity and hyperuricemia, and to analyze the potential mediating role of total cholesterol (TC), thereby providing a new theoretical basis for the early prevention ...
Xiying Huang, Xiying Huang, Daojun Yu
doaj   +1 more source

Factors Related to Clinical Hypothyroid Severity in Thyroid Cancer Patients after Thyroid Hormone Withdrawal

, 2011
Thyroid hormone withdrawal (THW) to stimulate thyrotropin ( TSH) secretion produces acute thyroid hormone deficiency in patients who have undergone thyroidectomy for differentiated thyroid cancer (DTC), but not all patients developed clinically overt ...
吳允升;林時逸;許惠恒;宋育民;林彥宏;吳誠中;張文道, WU, VIN-CENT;LIN, SHIH-YI;SHEU, WAYNE HUEY-HERNG;SONG, YUH-MIN;LIN, YEN-HUNG;WU, CHENG-CHUNG;CHANG, WEN-DAU   +1 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Resistance to thyroid hormone beta (R243Q) with autoimmune primary hypothyroidism: report of a kindred [PDF]

Archives of Endocrinology and Metabolism
The syndrome of resistance to thyroid hormone beta (RTHβ) is characterized by impaired tissue responsiveness to thyroid hormone and manifests as non-suppressed thyrotropin despite elevated thyroid hormone levels.
Alpesh Goyal, Rahul Gupta, Rekha Singh
doaj   +1 more source

Thyroid Hormone Receptor Beta Gene Mutation (P453A) in a Family Producing Resistance to Thyroid Hormone

, 2008
Background: Resistance to thyroid hormone (RTH) is a dominantly inherited syndrome characterized by decreased responsiveness of target tissues to thyroid hormone. Two members of a Turkish family, a mother and son, had thyroid function tests suggestive of
J. Noel, Bayraktaroglu, T., N. Mukaddes, Alagol, F., N. Colak, Mulkaddes, N. M., Colak, N., T. Bayraktaroglu, F. Alagol, Refetoff, S., S. Refetoff, Noel, J.   +11 more
core   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Impaired sensitivity to thyroid hormones is associated with all-cause and cause-specific mortality among chronic kidney disease patients: results from National Health and Nutrition Examination Survey (NHANES) 2007–2012

Renal Failure
Background Resistance to thyroid hormone shows underlying mechanical link with chronic kidney disease (CKD) and is prevalent in CKD population. However, whether it attributes to mortality risk among CKD population is unknown.
Chan Liu, Xiaoxiao Zhu, Dingding Wang, Naya Huang, Wei Chen   +4 more
doaj   +1 more source

Characterization of a Low Affinity Thyroid Hormone Receptor Binding Site within the Rat GLUT4 Gene Promoter

, 2023
Previous studies have demonstrated that thyroid hormone (T3) stimulates insulin-responsive glucose transporter (GLUT4) transcription and protein expression in rat skeletal muscle.
Dohm, G. Lynis, Torrance, Christopher J., Usala, Stephen J., NC DOCKS at East Carolina University, Pessin, Jeffrey E.   +4 more
core  

Thyroid Hormone Receptor Mutations in Cancer and Resistance to Thyroid Hormone: Perspective and Prognosis [PDF]

, 2011
Thyroid hormone, operating through its receptors, plays crucial roles in the control of normal human physiology and development; deviations from the norm can give rise to disease. Clinical endocrinologists often must confront and correct the consequences
Martin L. Privalsky, Meghan D. Rosen
core   +1 more source

Association of Urinary pH With Overall Survival in Patients With Stage IV Cancer: A Single‐Center Retrospective Cohort Study

Cancer Nexus, EarlyView.
ABSTRACT Objective This single‐center retrospective cohort study evaluated whether, among patients with stage IV cancer who participated in a pragmatic “alkalization therapy”—defined as a low potential renal acid load diet plus oral sodium bicarbonate and/or potassium/sodium citrate—urinary pH was associated with long‐term survival.
Shion Kachi, Kazuyuki Suzuki, Reo Hamaguchi, Ryoko Narui, Hiromasa Morikawa, Hiromi Wada   +5 more
wiley   +1 more source