Results 71 to 80 of about 2,990,232 (287)

Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review [PDF]

, 2008
The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed.
Brand, H., van den, Kemp, B., Bruggeman, V., Debonne, M., Decuypere, E., Baarendse, P.J.J., E. DECUYPERE, V. BRUGGEMAN, M. DEBONNE, P.J.J. BAARENDSE, H. VAN DEN BRAND, B. KEMP   +11 more
core   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Regulatory harmonization: Evolution, globalization and future directions

British Journal of Clinical Pharmacology, EarlyView.
Regulatory harmonization has become an increasingly important and accepted approach to streamline regulatory review processes and expedite access to safe, effective and high‐quality medicines globally. This review explores the evolution and current status of regulatory harmonization, convergence and reliance initiatives.
Orin Chisholm, Elaine Y. L. Blair, Christine Y. Lu   +2 more
wiley   +1 more source

Relationship of thyroid hormones and metabolic parameters in euthyroid women

Turkish Journal of Family Practice
Objective: Thyroid hormones play a role in metabolic regulation, yet their associations with obesity and insulin resistance in euthyroid individuals remain unclear. This study aimed to evaluate the relationship between thyroid-stimulating hormone (TSH),
Fatma Nur Yürekten Sıcakyüz, Furkan Alp Eren, Kağan Güngör, Hacer Hicran Mutlu   +3 more
doaj   +1 more source

Syndromes of resistance to thyroid hormone

Клиническая и экспериментальная тиреоидология, 2013
Синдром резистентности к тиреоидным гормо нам (RTH) является наследственным синдромом, характеризующимся пониженной чувствительнос тью тканеймишеней к гормонам щитовидной желе зы.

doaj   +1 more source

Assessing kidney function for drug dosing in critical illness

British Journal of Clinical Pharmacology, EarlyView.
Kidney‐function assessment supports drug dosing in critical illness but does not directly measure drug clearance. Reduced creatinine generation, fluid shifts and rapidly changing filtration can make creatinine‐based estimates misleading, whereas genuinely augmented renal clearance can cause insufficient drug exposure. These processes can coexist.
Ming‐Shen Lin, Kuo‐Fan Liao
wiley   +1 more source

Thyroid-stimulating Hormone and Insulin Resistance: Their Association with Polycystic Ovary Syndrome without Overt Hypothyroidism

, 2017
Objective This study analyzed the effectiveness of the thyroid-stimulating hormone (TSH) as a predictor of insulin resistance (IR) and its association with the clinical and metabolic parameters of women with polycystic ovary syndrome (PCOS) without ...
Cristina Laguna Benetti-Pinto (4661203), Vanessa Berini Piccolo (12726428), Heraldo Garmes (12726431), Daniela Angerame Yela (4661212)   +3 more
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Sex-specific associations between obstructive sleep apnea and thyroid hormone sensitivity in euthyroid adults

Biology of Sex Differences
Background The relationship between obstructive sleep apnea (OSA) and thyroid hormone sensitivity remains unclear. Thyroid hormone sensitivity indices may reveal subclinical hypothalamic-pituitary-thyroid (HPT) axis dysregulation beyond conventional ...
Beini Zhou, Yixuan Wang, Yuhan Wang, Jingyi Zhang, Qingfeng Zhang, Ke Hu   +5 more
doaj   +1 more source