Results 21 to 30 of about 3,935,952 (212)
Thrombosis Journal, 2005 Background Thrombin generation assay was developed several years ago to mimic physiological coagulation mechanisms but it had important limitations. Thrombogram-Thrombinoscope assay using a fluorogenic substrate, allows obtaining thrombin generation ...
Leflem Lena +5 more
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Comparison of the coagulopathies associated with COVID‐19 and sepsis
Research and Practice in Thrombosis and Haemostasis, 2021 Background Coronavirus disease 2019 (COVID‐19) is associated with activation of coagulation that mainly presents as thrombosis. Sepsis is also associated with activation of coagulation that mainly presents as disseminated intravascular coagulation.
Robert A. Campbell +8 more
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Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]
, 2010 Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F. +8 more
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Research and Practice in Thrombosis and Haemostasis, 2022 Background Circulating tissue factor (TF)‐expressing extracellular vesicles (EVs) are associated with thrombosis in several diseases, such as coronavirus disease 2019 (COVID‐19). Activity assays have higher sensitivity and specificity compared to antigen
Sierra J. Archibald +3 more
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Journal of Cardiovascular Development and Disease, 2022 Background: Thrombosis with cardiovascular involvement is a crucial complication in COVID-19 infection. COVID-19 infects the host by the angiotensin converting enzyme-2 receptor (ACE2r), which is expressed in endothelial cells too.
Giovanni Cimmino +9 more
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Heparanase and Coagulation–New Insights
Rambam Maimonides Medical Journal, 2014 Heparanase, a β-D-endoglucuronidase abundant in platelets that was discovered 30 years ago, is an enzyme that cleaves heparan sulfate side chains on the cell surface and in the extracellular matrix. It was later recognized as being a pro-inflammatory and
Yona Nadir
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Isolation and primary cultures of human intrahepatic bile ductular epithelium [PDF]
, 1988 A technique for the isolation of human intrahepatic bile ductular epithelium, and the establishment of primary cultures using a serum- and growth-factor-supplemented medium combined with a connective tissue substrata is described.
A. E. Sirica +24 more
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Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis [PDF]
, 2018 Tachyzoite to bradyzoite development in Toxoplasma is marked by major changes in gene expression resulting in a parasite that expresses a new repertoire of surface antigens hidden inside a modified parasitophorous vacuole called the tissue cyst.
Hong, David +6 more
core +5 more sources
Heparanase—A Link between Coagulation, Angiogenesis, and Cancer
Rambam Maimonides Medical Journal, 2012 Heparanase that was cloned from and is abundant in the placenta is implicated in cell invasion, tumor metastasis, and angiogenesis. Recently we have demonstrated that heparanase may also affect the hemostatic system in a non-enzymatic manner.
Yona Nadir, Benjamin Brenner
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Frontiers in Immunology, 2023 ObjectiveIL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic arthritis (sJIA).
Audrey Cambon +24 more
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