Results 21 to 30 of about 3,940,286 (283)
Tissue Factor Encryption [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2006 Tissue factor (TF) encryption is the post-translational suppression of TF procoagulant activity (PCA) on the cell surface. There is emerging evidence of encrypted TF in normal blood associated with monocytes and platelets. Expression of this latent TF PCA during the propagation phase of blood coagulation may contribute to hemostasis.
openaire +2 more sources
Isolation and primary cultures of human intrahepatic bile ductular epithelium [PDF]
, 1988 A technique for the isolation of human intrahepatic bile ductular epithelium, and the establishment of primary cultures using a serum- and growth-factor-supplemented medium combined with a connective tissue substrata is described.
A. E. Sirica +24 more
core +1 more source
Perspectives in Microvascular Fluid Handling: Does the Distribution of Coagulation Factors in Human Myocardium Comply with Plasma Extravasation in Venular Coronary Segments? [PDF]
, 2010 Background: Heterogeneity of vascular permeability has been suggested for the coronary system. Whereas arteriolar and capillary segments are tight, plasma proteins pass readily into the interstitial space at venular sites.
Becker, Bernhard F. +8 more
core +1 more source
mTOR Promotes Tissue Factor Expression and Activity in EGFR-Mutant Cancer
Frontiers in Oncology, 2020 Mechanistic target of rapamycin (mTOR) signaling pathway mediates the function of oncogenic receptor tyrosine kinases (RTKs). We aimed to elucidate new role of mTOR in EGFR-mutant (EGFR-mut) non-small cell lung cancer (NSCLC) and glioblastoma (GBM) with ...
Ying Cong +4 more
doaj +1 more source
Frontiers in Immunology, 2023 Venous thromboembolism (VTE) is a leading cause of preventable deaths in hospitals, and its incidence is not decreasing despite extensive efforts in clinical and laboratory research. Venous thrombi are primarily formed in the valve pockets of deep veins,
Casper J.E. Wahlund +7 more
doaj +1 more source
Disseminated intravascular coagulation
Indian Journal of Anaesthesia, 2014 Disseminated intravascular coagulation (DIC) is a reflection of an underlying systemic disorder which affects the coagulation system, simultaneously resulting in pro-coagulant activation, fibrinolytic activation, and consumption coagulopathy and finally ...
A Venugopal
doaj +1 more source
Transcriptional repression by ApiAP2 factors is central to chronic toxoplasmosis [PDF]
, 2018 Tachyzoite to bradyzoite development in Toxoplasma is marked by major changes in gene expression resulting in a parasite that expresses a new repertoire of surface antigens hidden inside a modified parasitophorous vacuole called the tissue cyst.
Hong, David +6 more
core +5 more sources
Journal of Extracellular Vesicles, 2014 Microvesicles were isolated from the conditioned media of 3 cell lines (MDA-MB-231, AsPC-1 and A375) by ultracentrifugation at a range of relative centrifugal forces, and the tissue factor (TF) protein and activity, microvesicle number, size distribution
Camille Ettelaie +3 more
doaj +1 more source
Tissue factor release following traumatic brain injury drives thrombin generation
Research and Practice in Thrombosis and Haemostasis, 2022 Background Traumatic brain injury (TBI) results in neurovascular damage that initiates intrinsic mechanisms of hypercoagulation, which can contribute to the development of life‐threatening complications, such as coagulopathy and delayed thrombosis ...
W. Brad Hubbard +4 more
doaj +1 more source
Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]
, 2017 An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto +6 more
core +2 more sources