Results 21 to 30 of about 190,023 (93)

Robust Bayesian FDR Control using Bayes Factors, with Applications to Multi-tissue eQTL Discovery [PDF]

open access: yesarXiv, 2013
Motivated by the genomic application of expression quantitative trait loci (eQTL) mapping, we propose a new procedure to perform simultaneous testing of multiple hypotheses using Bayes factors as input test statistics. One of the most significant features of this method is its robustness in controlling the targeted false discovery rate (FDR) even under
arxiv  

Cell-level modelling of homeostasis in confined epithelial monolayers [PDF]

open access: yesarXiv
Tissue homeostasis, the biological process of maintaining a steady state in tissue via control of cell proliferation, death, and metabolic function, is essential for the development, growth, maintenance, and proper function of living organisms. Disruptions to this process can lead to serious diseases and even death.
arxiv  

Statistical Problems in a Paper on Variation In Cancer Risk Among Tissues, and New Discoveries [PDF]

open access: yesarXiv, 2015
Tomasetti and Vogelstein (2015) collected data on 31 different tissue types and found a correlation of 0.8 between the logarithms of the incidence of cancer (LCI), and the estimated number of stem cell divisions in those tissues (LSCD). Some of their conclusions however are statistically erroneous. Their excess risk score, "ERS" (log10 LCI x log10 LSCD)
arxiv  

Applications of aligned nanofiber for tissue engineering [PDF]

open access: yesarXiv
In tissue engineering, we seek to address comprehensive tissue repair and regeneration needs. Aligned nanofibers have emerged as powerful and versatile tools, attributable to their structural and biochemical congruence with the natural extracellular matrix (ECM).
arxiv  

Micromechanical Experimental and Numerical Studies of Collagen Fibers Failure in Arterial Tissue [PDF]

open access: yesarXiv, 2018
Arterial tissue failures lead to a number of clinical conditions that develop rapidly and unpredictably in vivo. Structural components and their interfacial mechanical strength of arterial tissue play a critical role in the process of arterail delamination.
arxiv  

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