Results 21 to 30 of about 17,692,743 (361)
Thrombosis Journal, 2005 Background Thrombin generation assay was developed several years ago to mimic physiological coagulation mechanisms but it had important limitations. Thrombogram-Thrombinoscope assay using a fluorogenic substrate, allows obtaining thrombin generation ...
Leflem Lena +5 more
doaj +1 more source
Value of multimodal MRI in evaluation of tissue factor expression in glioblastoma
Di-san junyi daxue xuebao, 2020 Objective To explore the correlation between multimodal magnetic resonance imaging (MRI) and expression of tissue factor (TF) in glioblastoma (GBM), and investigate the values of MRI parameters as imaging markers for TF.
ZHOU Bo +5 more
doaj +1 more source
Molecules, 2023 Chuanxiong rhizoma (CX) has been utilized for centuries as a traditional herb to treat blood stasis syndromes. However, the pharmacological mechanisms are still not completely revealed.
Shasha He +3 more
doaj +1 more source
Tissue Factor and Cancer: Regulation, Tumor Growth, and Metastasis
Seminars in Thrombosis and Hemostasis, 2019 There is a strong relationship between tissue factor (TF) and cancer. Many cancer cells express high levels of both full-length TF and alternatively spliced (as) TF. TF expression in cancer is associated with poor prognosis.
Y. Hisada, N. Mackman
semanticscholar +1 more source
Comparison of the coagulopathies associated with COVID‐19 and sepsis
Research and Practice in Thrombosis and Haemostasis, 2021 Background Coronavirus disease 2019 (COVID‐19) is associated with activation of coagulation that mainly presents as thrombosis. Sepsis is also associated with activation of coagulation that mainly presents as disseminated intravascular coagulation.
Robert A. Campbell +8 more
doaj +1 more source
Frontiers in Immunology, 2023 ObjectiveIL-1β is a leaderless cytokine with poorly known secretory mechanisms that is barely detectable in serum of patients, including those with an IL-1β-mediated disease such as systemic juvenile idiopathic arthritis (sJIA).
Audrey Cambon +24 more
doaj +1 more source
Tissue factor at the crossroad of coagulation and cell signaling
Journal of Thrombosis and Haemostasis, 2018 The tissue factor (TF) pathway plays a central role in hemostasis and thrombo‐inflammatory diseases. Although structure‐function relationships of the TF initiation complex are elucidated, new facets of the dynamic regulation of TF's activities in cells ...
H. Zelaya +4 more
semanticscholar +1 more source
Research and Practice in Thrombosis and Haemostasis, 2022 Background Circulating tissue factor (TF)‐expressing extracellular vesicles (EVs) are associated with thrombosis in several diseases, such as coronavirus disease 2019 (COVID‐19). Activity assays have higher sensitivity and specificity compared to antigen
Sierra J. Archibald +3 more
doaj +1 more source
Biomolecules, 2021 The vast majority of coagulation factor VII (FVII), a trypsin-like protease, circulates as the inactive zymogen. Activated FVII (FVIIa) is formed upon proteolytic activation of FVII, where it remains in a zymogen-like state and it is fully activated only
Jesper J. Madsen, Ole H. Olsen
doaj +1 more source
The abnormalities of coagulation and fibrinolysis in acute lung injury caused by gas explosion
Kaohsiung Journal of Medical Sciences, 2020 Acute lung injury (ALI) caused by gas explosion is common, and warrants research on the underlying mechanisms. Specifically, the role of abnormalities of coagulation and fibrinolysis in this process has not been defined.
Lin‐Qiang Tian +14 more
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