Results 61 to 70 of about 3,940,286 (283)

Transforming Growth Factor Alpha Stimulation of Mucosal Tissue Cultures from Head and Neck Squamous Cell Carcinoma Patients Increases Chemoresistance to Cisplatin [PDF]

, 2010
The monoclonal epidermal growth factor receptor ( EGFR) antibody cetuximab (Erbitux(TM)) was recently approved by the European Medicines Agency for the treatment of recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) in combination ...
Baumeister, Philipp, Harreus, Ulrich, Reiter, Maximilian, Schwenk-Zieger, Sabina   +3 more
core   +1 more source

RT‐PCR–Based Detection of Bone Marrow Involvement in Ewing Sarcoma: Diagnostic Validity and Prognostic Relevance

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background In Ewing sarcoma (EwS), metastases, including those to bone marrow (BM), are the main factors influencing prognosis. Although reverse transcription polymerase chain reaction (RT‐PCR) offers greater sensitivity, the current EWING protocol defines BM metastases solely using light microscopic detection.
Thanh Pham, Andreas Ranft, Victor Rechl, Susanne Jabar, Wolfgang Hartmann, Kim Falkenberg, Heribert Jürgens, Norbert Graf, Torsten Keßler, Markus Metzler, Thomas Klingebiel, Thorsten Simon, Martin Benesch, Uta Dirksen   +13 more
wiley   +1 more source

Characterisation of tissue factor-bearing extracellular vesicles with AFM: comparison of air-tapping-mode AFM and liquid Peak Force AFM

Journal of Extracellular Vesicles, 2013
Introduction: Extracellular vesicles (EVs) are shed from cells and carry markers of the parent cells. Vesicles derived from cancer cells reach the bloodstream and locally influence important physiological processes.
Julie Hardij, Francesca Cecchet, Alexandre Berquand, Damien Gheldof, Christian Chatelain, François Mullier, Bernard Chatelain, Jean-Michel Dogné   +7 more
doaj   +1 more source

Clinical Correlates of Anxiety and Depression After Diagnosis of a Pediatric Brain Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The prevalence and clinical correlates of symptoms of anxiety and depression in pediatric patients with brain tumors are not well described. We aimed to identify clinical characteristics that are correlated with elevated symptoms of anxiety and depression following initial diagnosis.
Bryony J. Lucas, Se‐Kang Kim, Joan Yu, Ana Sofia C. Ibarrola, Heather H. Stancel, Kavyaa Choudry, Mary Elizabeth Moody, Krystal K. Christopher, David R. Grosshans, Arnold C. Paulino, Guillermo Aldave, M. Fatih Okcu, Murali M. Chintagumpala, Austin L. Brown, Michael E. Scheurer, Kimberly P. Raghubar, Lisa S. Kahalley   +16 more
wiley   +1 more source

Super-resolution photoacoustic fluctuation imaging with multiple speckle illumination [PDF]

, 2015
In deep tissue photoacoustic imaging, the spatial resolution is inherently limited by acoustic diffraction. Moreover, as the ultrasound attenuation increases with frequency, resolution is often traded-off for penetration depth.
Allain, Marc, Bossy, Emmanuel, Chaigne, Thomas, Gateau, Jérôme, Gigan, Sylvain, Katz, Ori, Sentenac, Anne   +6 more
core   +3 more sources

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell, Jessica Liang, Liliana Preiss, Angela Rivers, Jane S. Hankins, Allison King, Justin Williams, Michael B. Potter, Danielle Hessler   +8 more
wiley   +1 more source

A First-In-Class, Humanized Antibody Targeting Alternatively Spliced Tissue Factor: Preclinical Evaluation in an Orthotopic Model of Pancreatic Ductal Adenocarcinoma

Frontiers in Oncology, 2021
In 2021, pancreatic ductal adenocarcinoma (PDAC) is the 3rd leading cause of cancer deaths in the United States. This is largely due to a lack of symptoms and limited treatment options, which extend survival by only a few weeks.
Clayton S. Lewis, Aniruddha Karve, Kateryna Matiash, Timothy Stone, Jingxing Li, Jordon K. Wang, Henri H. Versteeg, Bruce J. Aronow, Syed A. Ahmad, Pankaj B. Desai, Vladimir Y. Bogdanov   +10 more
doaj   +1 more source

Age-related loss of skeletal muscle function; impairment of gene expression. [PDF]

, 2004
Mechano Growth Factor (MGF) is derived from the insulin-like growth factor (IGF-I) but its sequence differs from the systemic IGF-I produced by the liver. MGF is expressed by mechanically overloaded muscle and is involved in tissue repair and adaptation.
Goldspink, G
core  

Predicting survival from colorectal cancer histology slides using deep learning: A retrospective multicenter study [PDF]

, 2019
BACKGROUND: For virtually every patient with colorectal cancer (CRC), hematoxylin-eosin (HE)-stained tissue slides are available. These images contain quantitative information, which is not routinely used to objectively extract prognostic biomarkers.
Brenner, H., Chang-Claude, J., Charoentong, P., Ferber, D., Gaiser, T., Halama, N., Herpel, E., Hoffmeister, M., Jansen, L., Jäger, D., Kather, J. N., Krisam, J., Luedde, T., Marx, A., Reyes-Aldasoro, C. C., Valous, N. A., Weis, C. A., Zörnig, I.   +17 more
core   +2 more sources

Tissue factor and cancer [PDF]

Thrombosis Research, 2012
The hemostatic system is involved in multiple interactions with transformed cells that progress from a dormant, non-vascularized tumor to highly metastatic phenotypes. Oncogenic transformations up regulate not only the initiator of the coagulation cascade, tissue factor (TF), but also induce other molecules that are required for TF's direct cell ...
openaire   +2 more sources