Results 11 to 20 of about 17,677,818 (279)
LOCAL IMMUNITY BY TISSUE-RESIDENT CD8+ MEMORY T CELLS [PDF]
Frontiers in Immunology, 2012 Microbial infection primes a CD8+ cytotoxic T cell response that gives rise to a long-lived population of circulating memory cells able to provide protection against systemic reinfection.
Thomas eGebhardt, Laura K Mackay
doaj +6 more sources
Tissue-resident memory T cells in renal autoimmune diseases [PDF]
Frontiers in Immunology, 2023 The discovery of tissue-resident memory T cells (TRM cells) reinterpreted the potential of human tissue-specific immunity. Following T cell receptor (TCR) activation and clonal expansion, effector T cells migrate to peripheral tissues where they remain ...
Pauline Ginsberg +2 more
doaj +4 more sources
Tissue-Resident Memory T Cells in Antifungal Immunity [PDF]
Frontiers in Immunology, 2021 Fungi are an integral part of the mammalian microbiota colonizing most if not all mucosal surfaces and the skin. Maintaining stable colonization on these surfaces is critical for preventing fungal dysbiosis and infection, which in some cases can lead to ...
Salomé LeibundGut-Landmann +1 more
doaj +4 more sources
Gut tissue-resident memory T cells in coeliac disease [PDF]
Scandinavian Journal of Immunology, 2022 This mini-review describes observations of the 1990ies with culturing of gluten-specific and astrovirus-specific CD4+ T cells from duodenal biopsies from subjects who presumably had a long time between the exposure to gluten or astrovirus antigens and ...
Sollid, Ludvig Magne
core +5 more sources
Heterogeneity of tissue resident memory T cells
Immunology Letters, 2022 Non-lymphoid organs, in mice and humans, contain CD8+ tissue-resident memory T (TRM) cells. They play important roles in tissue homoeostasis as well as defence against infections and cancer. TRM cells have common characteristics that enables their tissue
Iannacone M. +3 more
core +3 more sources
Tissue-resident memory T cells in the kidney
Seminars in Immunopathology, 2022 The identification of tissue-resident memory T cells (T(RM) cells) has significantly improved our understanding of immunity. In the last decade, studies have demonstrated that T(RM) cells are induced after an acute T-cell response, remain in peripheral ...
Ginsberg, P +9 more
core +3 more sources
Tissue Adaptations of Memory and Tissue-Resident Gamma Delta T Cells [PDF]
Frontiers in Immunology, 2018 Epithelial and mucosal barriers are critical interfaces physically separating the body from the outside environment and are the tissues most exposed to microorganisms and potential inflammatory agents.
Camille Khairallah +2 more
doaj +3 more sources
Editorial: Tissue Resident Memory T Cells
Frontiers in Immunology, 2019 Fathia Mami-Chouaib +2 more
doaj +3 more sources
Bone marrow T cells and the integrated functions of recirculating and tissue-resident memory T cells [PDF]
Frontiers in Immunology, 2016 Changes in T cell trafficking accompany the naïve to memory T cell antigen-driven differentiation, which remains an incompletely defined developmental step. Upon priming, each naïve T cell encounters essential signals–i.e.
Francesca eDi Rosa, Thomas eGebhardt
doaj +2 more sources
Human circulating and tissue-resident memory CD8+ T cells [PDF]
Nature Immunology, 2023 Our current knowledge of human memory CD8+ T cells is derived largely from studies of the intravascular space. However, emerging data are starting to challenge some of the dogmas based on this work, suggesting that a conceptual revision may be necessary.
Betts, Michael R. +8 more
core +4 more sources