Regulation of Toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia
Background Hypoxic-ischemic (HI) brain injury remains a major problem in newborns, resulting in increased risk of neurological disorders. Neonatal HI triggers a broad inflammatory reaction in the brain, including activation of the innate immune system ...
Naylor Andrew S +4 more
doaj +1 more source
Association of GT microsatellite polymorphism in TLR 2 gene with leprosy [PDF]
Background Toll-like receptor 2 (TLR2) is critical in bringing up immune responses to mycobacterial infections. The mutations in TLR2 are known to confer susceptibility for severe infection with mycobacteria. TLR2 may diminish response to mycobacterial proteins and place individuals at risk of developing leprosy.
Suryadevara NC +4 more
openaire +2 more sources
Temperature Measurement and Phonon Number Statistics of a Nanoelectromechanical Resonator [PDF]
Measuring thermodynamic quantities can be easy or not, depending on the system that is being studied. For a macroscopic object, measuring temperatures can be as simple as measuring how much a column of mercury rises when in contact with the object.
de Oliveira, M. C. +2 more
core +2 more sources
The presence of preceding cardiovascular disease (CVD) is an important risk factor for the severe clinical course of COVID-19. In addition, COVID-19 is often aggravated by cardiovascular complications.
Alla V. Shevchenko +5 more
doaj +1 more source
Mycobacterium tuberculosis multi-drug-resistant strain M induces IL-17+ IFNγ- CD4+ T cell expansion through an IL-23 and TGF-β-dependent mechanism in patients with MDR-TB tuberculosis [PDF]
We have previously reported that T cells from patients with multidrug-resistant tuberculosis (MDR-TB) express high levels of IL-17 in response to the MDR strain M(Haarlem family) of Mycobacterium tuberculosis (M.tuberculosis).
Balboa, Luciana +13 more
core +2 more sources
Sialylation of Helicobacter bizzozeronii lipopolysaccharides modulates Toll-like receptor (TLR) 2 mediated response [PDF]
Sialic acid in lipopolysaccharides (LPS) of mucosal pathogens is known to be an important virulence factor. Few strains of Helicobacter pylori express sialyl-Lewis-X and we have reported that human and canine Helicobacter bizzozeronii strains express sialyl-lactoseamine in their LPS.
Revez Joana +3 more
openaire +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
PENGARUH SUPLEMENTASI ISOFLAVON KEDELAI TERHADAP WANITA PENDERITA AKNE VULGARIS : Kajian Jumlah Lesi, Dihydrotestosterone, Toll-Like Receptor-2, dan Interleukin-8 [PDF]
Latar belakang : Akne vulgaris (AV) merupakan penyakit inflamasi kulit yang paling sering dijumpai. Isoflavon kedelai telah terbukti sebagai antiandrogen dan antiinflamasi.
RIYANTO, Puguh
core
Dog skin parasite load, TLR-2, IL-10 and TNF-α expression and infectiousness [PDF]
Visceral leishmaniosis is a zoonotic disease that is transmitted by Lutzomyia longipalpis sandflies. Dogs are the main peri-urban reservoir of the disease, and progression of canine leishmaniosis is dependent on the type of immune response elaborated ...
Avanço, S. V. +14 more
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source

