Results 71 to 80 of about 148,086 (284)

Immune Modulatory Effects of Probiotic Streptococcus thermophilus on Human Monocytes

Biologics, 2021
Ingesting probiotics contributes to the development of a healthy microflora in the GIT with established benefits to human health. Some of these beneficial effects may be through the modulation of the immune system.
Narges Dargahi, Joshua C. Johnson, Vasso Apostolopoulos   +2 more
doaj   +1 more source

Dynamic current susceptibility as a probe of Majorana bound states in nanowire-based Josephson junctions

, 2017
We theoretically study a Josephson junction based on a semiconducting nanowire subject to a time-dependent flux bias. We establish a general density matrix approach for the dynamical response of the Majorana junction and calculate the resulting flux ...
Aguado, Ramon, Bouchiat, Helene, Dmytruk, Olesia, Simon, Pascal, Trif, Mircea   +4 more
core   +2 more sources

The in vitro effects of resistin on the innate immune signaling pathway in isolated human subcutaneous adipocytes [PDF]

, 2007
Context: Obesity-associated inflammation is a contributory factor in the pathogenesis of type 2 diabetes mellitus (T2DM); the mechanisms underlying the progression to T2DM are unclear.
Adam R. Baker, Alison L. Harte, Aranda, Asensio, Baan, Banerjee, Bokarewa, Borst, Bradford, Christine M. Kusminski, Creely, Curat, Einstein, Ffolliott M. Fisher, Fu, Graveleau, Hirosumi, Hotamisligil, Kusminski, Lehrke, Li, Lin, McTernan, McTernan, Nancy F. da Silva, Pagano, Patel, Philip G. McTernan, Rae, Rajala, Rajala, Rangwala, Reilly, Ridker, Roeder, Sato, Savage, Shetty, Silswal, Steppan, Steppan, Steven J. Creely, Sudhesh Kumar, Tzou, Weisberg, Xu   +45 more
core   +1 more source

Bacteroides fragilis signals through Toll-like receptor (TLR) 2 and not through TLR4 [PDF]

Journal of Medical Microbiology, 2009
Although it is desirable to identify the interactions between endotoxin/LPS and the innate immune mechanism, it is often not possible to isolate these interactions from other cell wall-related structures of protein or polysaccharide origin. There is no universally accepted method to extract different LPSs from different bacteria, and their natural ...
Alhawi, M, Stewart, J, Erridge, C, Patrick, S, Poxton, IR   +4 more
openaire   +3 more sources

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Tunneling through ultrasmall NIS junctions in terms of Andreev reflection: a nonlinear response approach

, 1995
The Andreev current through an ultrasmall NIS junction is calculated in a systematic way by means of a nonlinear response approach basing on the elementary Hamiltonian of quasiparticle tunneling.
Andreev, Averin, Averin, Averin, Blonder, Devoret, Grabert, Grabert, Hanke, Hekking, Hekking, Hekking, Hesse, Ingold, Krech, Lafarge, Rogovin, Schoeller, Tinkham   +18 more
core   +1 more source

TLR-2 Recognizes Propionibacterium acnes CAMP Factor 1 from Highly Inflammatory Strains

PLOS ONE, 2016
Propionibacterium acnes (P. acnes) is an anaerobic, Gram-positive bacteria encountered in inflammatory acne lesions, particularly in the pilosebaceous follicle. P. acnes triggers a strong immune response involving keratinocytes, sebocytes and monocytes, the target cells during acne development. Lipoteicoic acid and peptidoglycan induce the inflammatory
Lheure, Coralie, Grange, Philippe Alain, Ollagnier, Guillaume, Morand, Philippe, Désiré, Nathalie, Sayon, Sophie, Corvec, Stéphane, Raingeaud, Jöel, Marcelin, Anne-Geneviève, Calvez, Vincent, Khammari, Amir, Batteux, Frédéric, Dréno, Brigitte, Dupin, Nicolas   +13 more
openaire   +6 more sources

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association

Frontiers in Cellular and Infection Microbiology, 2015
To survive in macrophages, Coxiella burnetii hijacks the activation pathway of macrophages. Recently, we have demonstrated that C. burnetii, via its lipopolysaccharide (LPS), avoids the activation of p38α-MAPK through an antagonistic engagement of Toll ...
Filippo eConti, Nicolas eBoucherit, Veronica eBaldassarre, Virginie eTrouplin, Giovanna eMottola, Rudolf eToman, Jean-louis eMege, Eric eGhigo   +7 more
doaj   +1 more source

Trichinella spiralis galectin binding to toll-like receptor 4 induces intestinal inflammation and mediates larval invasion of gut mucosa

Veterinary Research, 2023
Previous studies showed that Trichinella spiralis galectin (Tsgal) facilitates larval invasion of intestinal epithelium cells (IECs). However, IEC proteins binding with Tsgal were not identified, and the mechanism by which Tsgal promotes larval invasion ...
Kai Ning Ma, Yao Zhang, Zhao Yu Zhang, Bo Ning Wang, Yan Yan Song, Lu Lu Han, Xin Zhuo Zhang, Shao Rong Long, Jing Cui, Zhong Quan Wang   +9 more
doaj   +1 more source