Results 111 to 120 of about 156,491 (330)

Spirochetal Lipoproteins and Immune Evasion. [PDF]

, 2017
Spirochetes are a major threat to public health. However, the exact pathogenesis of spirochetal diseases remains unclear. Spirochetes express lipoproteins that often determine the cross talk between the host and spirochetes.
Boyadjian, Ani, Christodoulides, Alexei, Kelesidis, Theodoros   +2 more
core   +1 more source

Toll-Like Receptor 4, 2, and Interleukin 1 Receptor Associated Kinase4: Possible Diagnostic Biomarkers in Myelodysplastic Syndrome Patients

Advanced Biomedical Research
Background: Myelodysplastic syndrome (MDS) is a clonal hematologic disorder that requires the integration of morphologic, cytogenetic, hematologic, and clinical findings for a successful diagnosis.
Parvin Khalilian, Nahid Eskandari, Mohammad Jafar Sharifi, Mohammad Soltani, Pardis Nematollahi   +4 more
doaj   +1 more source

Systemic TLR2 tolerance enhances central nervous system remyelination

Journal of Neuroinflammation, 2019
Background Multiple sclerosis (MS) is a central nervous system (CNS) autoimmune disease characterized by both inflammatory demyelination and impaired remyelination.
Nicholas J. Wasko, Meghan Horne Kulak, Debayon Paul, Alexandra M. Nicaise, Stephen T. Yeung, Frank C. Nichols, Kamal M. Khanna, Stephen Crocker, Joel S. Pachter, Robert B. Clark   +9 more
doaj   +1 more source

Multi‐Omics Insights Into the Role of Fructooligosaccharides Supplementation in Alleviating Salpingitis in Laying Hens

Animal Research and One Health, EarlyView.
Multi‐omics analysis revealed that FOS supplementation increased the abundance of Phascolarctobacterium, GCA‐900066575, Shuttleworthia, Olsenella, Eubacterium_hallii_group while decreasing Alistipes. It also influenced the metabolism of S‐lactoylglutathione, p‐cresol glucuronate, 2‐phenylethanol glucuronide, propionic acid, dulcitol, and inhibited the ...
Dan Song, Tao Duan, Rong Li, Xiaoqiu Wang, Fengdong Zhang, Jia Feng, Lin Qiao, Junlin Cheng, Lixian Chen, Aike Li, Yuna Min, Weiwei Wang   +11 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Active Components of Leptospira Outer Membrane Protein LipL32 to Toll-Like Receptor 2

Scientific Reports, 2017
Proteins belonging to the toll-like receptor (TLR) family, particularly TLR2, are the major components of innate immunity against Leptospira infection.
Shen-Hsing Hsu, Cheng-Chieh Hung, Ming-Yang Chang, Yi-Ching Ko, Huang-Yu Yang, Hsiang-Hao Hsu, Ya-Chung Tian, Li-Fang Chou, Rong-Long Pan, Fan-Gang Tseng, Chih-Wei Yang   +10 more
doaj   +1 more source

Integrative single cell RNA‐sequencing and spatial transcriptomics uncovers distinct macrophage‐fibroblast cross‐talk in human hip synovium between patients with femoroacetabular impingement and osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objectives Femoroacetabular impingement (FAI) and synovitis have been recognized as essential factors for developing osteoarthritis (OA) in the hip joints. However, little is known about altered synovial cellular compositions, their associated transcriptomic profiles, and cell‐cell interactions in FAI and hip OA.
Gulzada Kulzhanova, Alexis Klee, Mina Botros, Victoria L. Hansen, John Reuter, Eliya Tazreena Tashbib, Eloise Fadial, Benjamin F. Ricciardi, Brian Giordano, Chia‐Lung Wu   +9 more
wiley   +1 more source

TLR2 signaling is required for the innate, but not adaptive response to LVS clpB

Frontiers in Immunology, 2014
Toll-like receptor 2 (TLR2) is the best characterized pattern-recognition receptor for the highly pathogenic intracellular bacterium, Francisella tularensis.
Lydia Marie Roberts, Hannah E Ledvina, Gregory eSempowski, Jeffrey eFrelinger   +3 more
doaj   +1 more source

Hyaluronan Fragments Act as an Endogenous Danger Signal by Engaging TLR2 [PDF]

, 2006
Kara Scheibner, Michael A. Lutz, Sada Boodoo, Matthew J. Fenton, Jonathan D. Powell, Maureen R. Horton   +5 more
openalex   +1 more source

Decision letter: SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway

, 2021
C. C. Allen
openalex   +1 more source