Results 181 to 190 of about 156,491 (330)

Decision letter for "Tlr2/4‐mediated Hyperinflammation Promotes Cherubism‐like Jawbone Expansion in Sh3bp2 ( P416R ) Knockin Mice"

, 2021

openalex   +1 more source

Anti-inflammatory protein TSG-6 secreted by bone marrow mesenchymal stem cells attenuates neuropathic pain by inhibiting the TLR2/MyD88/NF-κB signaling pathway in spinal microglia [PDF]

, 2020
Hao Yang, Lingmin Wu, Huimin Deng, Yuanli Chen, Huanping Zhou, Meiyun Liu, Shaochen Wang, Zheng Li, Lina Zhu, Xin Lv   +9 more
openalex   +1 more source

Comparative Transcriptomic Analysis of Human Macrophages During Mycobacterium avium Versus Mycobacterium tuberculosis Infection

Molecular Microbiology, EarlyView.
Human macrophage transcriptomic responses to Mycobacterium avium (Mav), a major cause of nontuberculous lung disease, were compared to Mycobacterium tuberculosis (Mtb). Both infections activated overlapping immune pathways, including cytokine signaling and GPCRs involved in lipid metabolism, while phospholipases were more strongly regulated by Mav and ...
Gül Kilinç, Robin H. G. A. van den Biggelaar, Tom H. M. Ottenhoff, Leon H. Mei, Anno Saris   +4 more
wiley   +1 more source

New roles for TLR2 [PDF]

Nature Reviews Immunology, 2012
openaire   +2 more sources

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

Oral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du, Zi Yang, Yang Yang, Chunmei Zhang, Hideaki Kagami, Xianqi Li, Liang Hu, Junji Xu, Jian Zhou   +8 more
wiley   +1 more source

The function of Toll-like receptor 2 in control of transcriptome responses to the microbiome and microbiome composition. [PDF]

Anim Microbiome
Liu L, Spaink HP.
europepmc   +1 more source

Porphyromonas gingivalis GroEL exacerbates orthotopic allograft transplantation vasculopathy via impairment of endothelial cell function

Molecular Oral Microbiology, EarlyView.
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai, Chun‐Yao Huang, Yi‐Ting Tsai, Chun‐Ming Shih, Ze‐Hao Lai, Chen‐Wei Liu, Yi‐Wen Lin, Feng‐Yen Lin   +7 more
wiley   +1 more source

An underlying mechanism of bovine mastitis: PGE₂ regulates <i>Staphylococcus aureus</i>-induced inflammatory response through TLR2, TLR4, and NLRP3 in macrophages. [PDF]

Vet Q
Gong Z, Yu Z, Ren P, Zhang S, Gao R, Zhao J, Wang Y, Qin S, Bao W, Shuang F.   +9 more
europepmc   +1 more source

Hyperglycemia enhances group B Streptococcus pathogenicity by impairing TLR2 expression and chemotactic response in the human placenta

Rodrigo Jiménez‐Escutia, Arumi Villafuerte-Pérez, Donovan Vargas-Alcantar, Karina Martínez-Garfias, Samara Rodríguez‐Flores, Pilar Velázquez-Sánchez, Amaury Fortanel-Fonseca, Rodrigo Zamora‐Escudero, Marcela Islas‐López, Ismael Mancilla‐Herrera, Lorenza Dı́az, Verónica Zaga‐Clavellina, Andrea Olmos‐Ortiz   +12 more
openalex   +1 more source

Adenovirus Vector-Induced Innate Inflammatory Mediators, MAPK Signaling, As Well As Adaptive Immune Responses Are Dependent upon Both TLR2 and TLR9 In Vivo [PDF]

, 2008
Daniel M. Appledorn, Sonika Patial, Aaron J. McBride, Sarah Godbehere, Nico van Rooijen, Narayanan Parameswaran, Andrea Amalfitano   +6 more
openalex   +1 more source