Results 201 to 210 of about 151,127 (263)

CXCR4 involvement in neurodegenerative diseases [PDF]

, 2018
Karch, Celeste M., Wen, Natalie
core   +1 more source

Systematic Proteomic Characterization of EV‐A71‐Infected Mice Identifies Dynamic Molecular Changes and Therapeutic Targets

MedComm, Volume 7, Issue 4, April 2026.
Time‐resolved multi‐omics of EV‐A71‐infected BALB/c mice uncovered dynamic host responses, revealing rapid neutrophil extracellular traps (NETs) activation as a key event. Screened drugs (kinase inhibitors) suppressed viral replication in vitro and in vivo, suggesting the promise of targeting host phosphorylation networks as a viable antiviral strategy.
Wanjun Peng, Qiaochu Wang, Binbin Zhao, Lihong Zhang, Jing Wu, Xiaohui Wei, Na Rong, Zhaohua Wang, Kaihui Liu, Jiangfeng Liu, Juntao Yang, Jiangning Liu   +11 more
wiley   +1 more source

Toll-like receptor 2 (TLR2) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Ultrasonic repression of TRPA1-dependent astrocyte reactivity confers neuroprotection in models of Lewy body dementia. [PDF]

Transl Neurodegener
Kim JH, Lee K, Koo M, Kim D, Hong JK, Choi JY, Ko HS, Shin JH, Park JM, Park J, Lee Y.   +10 more
europepmc   +1 more source

In Vitro Modeling of Age‐Associated Lipid Mediator's Impact on Vascular Biology Following Platelet Concentrate Transfusion

Aging Cell, Volume 25, Issue 4, April 2026.
Age‐associated LPA affects adverse reactions and alters platelet and endothelial biology following platelet concentrate transfusion. Age‐associated LPC, S1P could be involved in adverse reactions, in platelet and endothelium biology following a PC transfusion.
Amelie Prier, Mailys Portier, Chloe Heranney, Nancy Kouadio, Charles‐Antoine Arthaud, Marie‐Ange Eyraud, Marco Heestermans, Justine Bertrand‐Michel, Hind Hamzeh‐Cognasse, Fabrice Cognasse, Anne‐Claire Duchez   +10 more
wiley   +1 more source

Programmable Antigen‐Specific Immunity via Self‐Adjuvanting Nanovaccines Co‐Delivering Immune Modulators

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito, Yoshiyuki Manabe, Shino Ohshima, Masatoshi Maeki, Manabu Tokeshi, Hiroshi Inaba, Kazunori Matsuura, Kazuya Kabayama, Yoshie Kametani, Koichi Fukase   +9 more
wiley   +2 more sources

<i><b>Muribaculum intestinale</b></i> <b>negatively impacts glioma growth in mice through the toll-like receptor 2</b>. [PDF]

Gut Microbes
Marrocco F, Cocozza G, Antonangeli F, Khan R, Pietropaolo G, Elkihel A, Favaretto G, Lin X, Mancinelli R, Busdraghi LM, Reccagni A, Scarno G, Sciumè G, Laffranchi M, Peng L, Iebba V, Sozzani S, D'Alessandro G, Limatola C.   +18 more
europepmc   +1 more source

Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy

Allergy, Volume 81, Issue 4, Page 1138-1148, April 2026.
We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt, Andrea Knorz, Katharina Meder, Simon Goller, Fabian Imdahl, Yamila Rocca, Matthias Goebeler, Pierre Khoueiry   +7 more
wiley   +1 more source

Immunomodulatory effects of cathelicidin in the gut–brain axis: A novel link between mucosal immunity and neuroinflammation

Experimental Physiology, Volume 111, Issue 4, Page 1733-1745, 1 April 2026.
Abstract Cathelicidins are evolutionarily conserved host defence peptides known for their dual antimicrobial and immunomodulatory functions. Among them, LL‐37 in humans and CRAMP in rodents have emerged as crucial regulators of both mucosal immunity and CNS inflammation.
Mehrdad Nourizadeh, Amir Arsalan Ghahari, Ehsan Zandi, Seyedeh Zeynab Rasouli, Shaghayegh Davari, Mobina Hoseinzadeh, Mir Alireza Nourazar   +6 more
wiley   +1 more source

Toll-like receptor 2 (TLR2) [PDF]

Science-Business eXchange, 2009
openaire   +1 more source