Aggregation and Propagation of α‐Synuclein in Parkinson's Disease: A Bibliometric Perspective
Mechanisms of aggregation and spreading of α‐syn in PD. Abbreviations: ATP, adenosine triphosphate; ROS, reactive oxygen species; SOD, superoxide dismutase; ALP, autophagosome‐lysosome fusion pathway; TNF, tumor necrosis factor; IL, interleukin; ICAM, intercellular cell adhesion molecule; IBD, inflammatory bowel disease. ABSTRACT Introduction Parkinson'
Xinyue Zhang +3 more
wiley +1 more source
Mitochondrial ROS-ER Stress Axis Governs IL-10 Production in Neutrophils and Regulates Inflammation in Murine <i>Chlamydia pneumoniae</i> Lung Infection. [PDF]
Chou B +8 more
europepmc +1 more source
A Mechanism for Neurodegeneration Induced by Group B Streptococci through Activation of the TLR2/MyD88 Pathway in Microglia [PDF]
Seija Lehnardt +9 more
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ABSTRACT Background and Objective This study employed Mendelian randomization (MR) to investigate the causal relationships between 4907 circulating proteins and hyperlipidemia, with the aim of identifying potential drug targets. Methods Instrumental variables were derived from genome‐wide association study (GWAS) data on 4907 circulating proteins ...
Hui Cheng, Dayuan Zhong
wiley +1 more source
Altered microRNA expression correlates with reduced TLR2/4-dependent periodontal inflammation and bone resorption induced by polymicrobial infection. [PDF]
Jeepipalli S +11 more
europepmc +1 more source
CD86, the double agent: Significance of CD86 expression in B‐cell malignancies
Abstract Bypassing the anti‐tumor functions of the immune system is one of the keys to tumor survival. Tumors, especially hematological tumors, produce or express factors that retune T and B cells to inhibit the immune response. Coreceptors CD28 and CTLA‐4, and their ligands, CD80 and CD86, are involved in the immunological synapse and play an ...
Gábor Barna +4 more
wiley +1 more source
Membrane receptors cluster phosphatidylserine to activate LC3-associated phagocytosis. [PDF]
Boada-Romero E +7 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) have gained increasing attention in recent years due to their pivotal role in both health and disease. Emerging from both eukaryotic and prokaryotic cells, EVs serve as essential mediators of intercellular communication, exceeding the simplistic interactions observed with individual molecules. In this comprehensive
Philipp Arnold +23 more
wiley +1 more source
Identifying pyroptosis-hub genes and immune infiltration in neonatal hypoxic-ischemic brain injury. [PDF]
Qin C +8 more
europepmc +1 more source
TLR2 Expression in Relation to IL-6 and IL-1
Ewa Jabłońska, Magdalena Marcińczyk
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