Results 211 to 220 of about 133,056 (344)

Connexin26 and 43 play a role in regulating pro-inflammatory events in the epidermis [PDF]

, 2019
Bartholomew, Christopher, García-Vega, Laura, Jan, Afnan, Martin, Patricia E., O'Shaughnessy, Erin M.   +4 more
core   +1 more source

Innate Immune Activation Is a Strong Suppressor of CCL22 and Impedes Regulatory T Cell–Dendritic Cell Interaction

Immunology, EarlyView.
During homeostasis, CCL22 is secreted by dendritic cells (DC), which mediate contacts between regulatory T cells (Treg) and DC to maintain immune balance. Activation of innate immunity via microbes or pattern recognition receptor (PRR) agonists induces the secretion of several soluble factors (e.g., type I and II interferons, IL‐10), which mediate ...
Ignazio Piseddu, Jan Gärtig, Stephan Eiber, Stefan Moder, Raffael Thaler, Matthias Thaler, Juliane Gruen, Marlies Vornhülz, Kevin Bahner, Luana Messa, Benjamin Kühnemuth, Jennifer Müller, Konstantin Schnell, Antonia Beimert, Carolin Perleberg, Natascha Röhrle, Maximilian Martin Ludwig Knott, Linda Hammann, Vanessa Wittmann, Patrick Layritz, Moritz Rapp, Carole Bourquin, Julia Mayerle, Stefan Endres, David Anz   +24 more
wiley   +1 more source

Oral Treatment With Heat Shock Protein 65‐Producing Lactococcus lactis Induces Regulatory T Cells, Modulating Inflammatory Response in Leishmania braziliensis Infection

Immunology, EarlyView.
Oral treatment with HSP65‐producing Lactococcus lactis after Leishmania braziliensis infection modulates inflammation by promoting lesion resolution through increased IL‐10 production and expansion of regulatory T cells. These findings highlight the potential of oral tolerance induction as a promising therapeutic strategy for chronic inflammatory ...
Camila Mattos Andrade, Ítalo da Silva Gonçalves, Maria Luiza das Neves Nascimento, Washington Luís Conrado Santos, Vasco Ariston Azevedo, Deborah Bittencourt Mothé, Juliana Perrone Menezes Fullam, Patrícia Sampaio Tavares Veras, Natalia Machado Tavares, Tatiani Uceli Maioli, Ana Maria Caetano Faria, Cláudia Ida Brodskyn   +11 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Involvement of ERK, p38 and NF‐κB signal transduction in regulation of TLR2, TLR4 and TLR9 gene expression induced by lipopolysaccharide in mouse dendritic cells

, 2002
Huazhang An, Yizhi Yu, Minghui Zhang, Hongmei Xu, Runzi Qi, Xiaoyi Yan, Shuxun Liu, Wenya Wang, Zhenghong Guo, Jun Guo, Zhihai Qin, Xuetao Cao   +11 more
openalex   +2 more sources

TLR2 and TLR4 Stimulation Differentially Induce Cytokine Secretion in Human Neonatal, Adult, and Murine Mononuclear Cells [PDF]

, 2004
Bianca Schaub, Abdelouahab Bellou, Fiona K. Gibbons, German Velasco, Monica Campo, Hongzhen He, Yurong Liang, Matthew W. Gillman, Diane R. Gold, Scott T. Weiss, David L. Perkins, Patricia W. Finn   +11 more
openalex   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Limosilactobacillus reuteri‐Fusobacterium nucleatum Interactions Modulate Biofilm Composition and Immunogenicity

Journal of Periodontal Research, EarlyView.
The coaggregation between L. reuteri and F. nucleatum modulates its immunogenicity and affects the latter's ability to coaggregate with late colonizers, altering the biofilm composition. ABSTRACT Aim The interactions between Limosilactobacillus reuteri and oral bacteria are poorly understood.
Luming Yang, Gopu Sriram, Ren Jie Jacob Chew, Kai Soo Tan   +3 more
wiley   +1 more source

The glycopeptide vancomycin does not enhance toll-like receptor 2 (TLR2) activation by Streptococcus pneumoniae [PDF]

, 2004
L.J. Moore
openalex   +1 more source

A Role for High Mobility Group Box 1 (HMGB1) Release in the Pathogenesis of Gastroesophageal Reflux Disease

Neurogastroenterology &Motility, EarlyView.
Incubation of esophageal epithelial cells with a weakly acidic (pH 5) bile salt (deoxycholic acid) induces translocation of HMGB1 from the nucleus to the cytosol, and its subsequent release from the cell. This process can be ameliorated by pre‐treatment with the antioxidant, curcumin.
Tom Leech, David Kelsell, Diana Blaydon, Philip Woodland, Madusha Peiris   +4 more
wiley   +1 more source