A Mechanism for Neurodegeneration Induced by Group B Streptococci through Activation of the TLR2/MyD88 Pathway in Microglia [PDF]
Seija Lehnardt+9 more
openalex +1 more source
Astrocyte in Neurological Disease: Pathogenesis and Therapy
This review provides comprehensive overview of astrocytes in neurological disorders. Astrocytes contribute to neurological disorders via A1/A2 polarization, inducing neuroinflammation, synaptic, and BBB dysfunction. Metabolic disturbances in glucose, lipid, and amino acid pathways leading to oxidative stress and mitochondrial damage.
Meihui Huang+4 more
wiley +1 more source
Royal jelly fermented by honeybee queen (Apis mellifera)-derived Lactobacillus panisapium M1 enhances macrophage phagocytosis through the TLR2/MAPK/SR signaling pathway. [PDF]
Nonobe S+5 more
europepmc +1 more source
Moraxella catarrhalis is internalized in respiratory epithelial cells by a trigger-like mechanism and initiates a TLR2- and partly NOD1-dependent inflammatory immune response [PDF]
Hortense Slevogt+10 more
openalex +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng+10 more
wiley +1 more source
Correction: Development of a subunit vaccine against the cholangiocarcinoma causing <i>Opisthorchis viverrini</i>: a computational approach. [PDF]
Shah M+12 more
europepmc +1 more source
CELLULAR OUTSIDE - INSIDE PAMP SIGNALLING THROUGH TLR2
Alina Grabiec+6 more
openalex +1 more source
Expression and function of TLR2, TLR4, and Nod2 in primary canine colonic epithelial cells [PDF]
Mathew P. Swerdlow+7 more
openalex +1 more source
Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley +1 more source