Macrophage migration inhibitory factor of zoonotic <i>Giardia duodenalis</i> triggers TLR4-MAPK/AKT/NLRP3 pathways to regulate inflammatory response. [PDF]
Chen M +12 more
europepmc +1 more source
Immunoinformatics‐Based Multi‐Epitope Vaccine Targeting Helicobacter Pylori
ABSTRACT Background The rising global incidence of Helicobacter pylori‐related diseases, particularly gastric cancer, underscores the urgent need for effective preventive vaccines, motivating the exploration of innovative immunoinformatic strategies to address this public health challenge.
Aytak Vahdat Khajeh Pasha +4 more
wiley +1 more source
Mechanisms of cellular senescence combined with molecular docking strategies: A biomarker study of potential therapeutic targets for allergic rhinitis. [PDF]
Chen Q +9 more
europepmc +1 more source
Bidirectional Pathogenesis Between AD and Periodontitis. Periodontal pathogens reach the brain via hematogenous/trigeminal/oral–intestinal pathways, triggering neuroinflammation and Aβ plaques to drive AD. Conversely, AD disrupts bone homeostasis (via Aβ, endocrine/autonomic dysregulation) to aggravate periodontitis.
Weidong Zhang +5 more
wiley +1 more source
Clostridium leptum attenuates allergic airway inflammation via tDC‒Treg axis activation in a murine model of gut dysbiosis-associated asthma. [PDF]
Ding H +7 more
europepmc +1 more source
New Insights Into the Evolution of Immune Adaptors in Murid Rodents
TIR domain‐containing adaptors were evolved under purifying selection in murine. Positively selected sites were identified in Mal and Myd88 genes. Reduced genetic diversity of each adaptor gene was observed in two rat populations. Shared polymorphisms were common phenomena in rat adaptors.
Qianqian Su, Zhenhua She, Yi Chen
wiley +1 more source
Allies in the Skin Defense System: The Role of Thread Cells in the Evolution of Hagfish (Myxiniformes). [PDF]
Marino S, Alesci A.
europepmc +1 more source
CXCR4 involvement in neurodegenerative diseases [PDF]
Karch, Celeste M., Wen, Natalie
core +1 more source

