Results 31 to 40 of about 19,241 (251)

Toll-like receptor signaling and SIGIRR in renal fibrosis upon unilateral ureteral obstruction. [PDF]

, 2011
Innate immune activation via IL-1R or Toll-like receptors (TLR) contibutes to acute kidney injury but its role in tissue remodeling during chronic kidney disease is unclear.
Skuginna Veronika, Mantovani Alberto, S. Clauss, Heni Eka Susanti, R. Allam, Skuginna, Veronika, Clauss, Sebastian, Susanti, Heni Eka, Ramanjaneyulu Allam, H. E. Susanti, Hans-Joachim Anders, Christoph Römmele, Sebastian Clauss, M. Lech, Veronika Skuginna, Clauss Sebastian, Cecilia Garlanda, Lech, Maciej, Ryu, Mi, Lech Maciej, Garlanda Cecilia, C. Garlanda, Ryu Mi, Römmele, Christoph, Heni Eka, Mantovani, Alberto, Alberto Mantovani, Anders Hans-Joachim, Allam Ramanjaneyulu, Maciej Lech, Cecilia Garl, M. Ryu, Susanti Heni Eka, A. Mantovani, Anders, Hans-Joachim, Mi Ryu, Allam, Ramanjaneyulu, Römmele Christoph, C. Römmele, H. J. Anders, Garlanda, Cecilia, V. Skuginna   +41 more
core   +1 more source

TLR2 activation by Porphyromonas gingivalis requires both PPAD activity and fimbriae [PDF]

, 2022
Porphyromonas gingivalis, a keystone oral pathogen implicated in development and progression of periodontitis, may also contribute to the pathogenicity of diseases such as arthritis, atherosclerosis, and Alzheimer's. P. gingivalis is a master manipulator
Grabiec, Aleksander, Bereta, Grzegorz, Potempa, Jan, Grabiec, Aleksander M, Bereta, Grzegorz P, Łagosz-Ćwik, Katarzyna B, Lamont, Richard J, Łagosz-Ćwik, Katarzyna, Wielento, Aleksandra, Lamont, Richard J., Eick, Sigrun   +10 more
core   +2 more sources

Toll-Like Receptor (TLR) 1, 2, and 6 Gene Polymorphisms Support Evidence of Innate Immune Factors in Schizophrenia

Neuropsychiatric Disease and Treatment, 2023
Carlo E Sotelo-Ramírez,1,2 Beatriz Camarena,2 Marco Antonio Sanabrais-Jiménez,2 Julio Uriel Zaragoza-Hoyos,2 Bruno Ordoñez-Martínez,2 Raul I Escamilla-Orozco,3 Beatriz Gómez-González4 1Posgrado en Biología Experimental, Universidad Autónoma Metropolitana-
Sotelo-Ramírez CE, Camarena B, Sanabrais-Jiménez MA, Zaragoza-Hoyos JU, Ordoñez-Martínez B, Escamilla-Orozco RI, Gómez-González B   +6 more
doaj  

Increased Expression of Toll-Like Receptor (TLR) 2 and TLR6 on Peripheral Blood Monocytes by Induction of Staphylococcal Enterotoxin B During Exacerbation of Atopic Dermatitis Patients

Clinical, Cosmetic and Investigational Dermatology, 2023
Fitria Salim,1,2 Hendra Gunawan,3 Oki Suwarsa,3 Endang Sutedja3 1Doctoral Study Program, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, Indonesia; 2Department of Dermatology and Venereology, Faculty of Medicine, Universitas Syiah Kuala,
Salim F, Gunawan H, Suwarsa O, Sutedja E
doaj  

Hyperexpression of TLR2 and TLR4 in patients with ischemic stroke in acute period of the disease

Медицинская иммунология, 2020
Pathogenesis of ischemic stroke  is actively  involved  in the  system  of innate immunity. Under conditions of cerebral  ischemia, a number of biologically  active  substances are  released  that  interact with innate immunity receptors, in particular ...
L. V. Gankovskaya, L. V. Stakhovskaya, V. V. Grechenko, E. A. Koltsova, O. S. Uvarova, M. D. Demina, T. V. Gromova, O. A. Svitich   +7 more
doaj   +1 more source

Structural and Functional Evidence for the Role of the TLR2 DD Loop in TLR1/TLR2 Heterodimerization and Signaling [PDF]

Journal of Biological Chemistry, 2006
The Toll/Interleukin-1 receptor (TIR) domain of the Toll-like receptors (TLRs) plays an important role in innate host defense signaling. The TIR-TIR platform formed by the dimerization of two TLRs promotes homotypic protein-protein interactions with additional cytoplasmic adapter molecules to form an active signaling complex resulting in the expression
Jitendra K, Gautam, , Ashish, Laurey D, Comeau, Joanna K, Krueger, Michael F, Smith   +4 more
openaire   +2 more sources

The association of rs4696480 polymorphism in TLR2 gene and Staphylococcus aureus skin colonization in children with atopic dermatitis

Український журнал Перинатологія і педіатрія, 2022
Topicality. Up to 90% of patients with atopic dermatitis are colonized with S. aureus, with S. aureus predominance being unique to atopic dermatitis. TLR2 play a role in the presentation of S. aureus antigens in a course of atopic dermatits. Purpose -
O.V. Mozyrska
doaj   +1 more source

Characterization and investigation of single nucleotide polymorphisms and a novel TLR2 mutation in the human TLR2 gene [PDF]

Human Molecular Genetics, 2007
In the innate immune system, TLR2 plays a central role for the response to a wide variety of microbial and endogenous danger signals. A considerable number of genetic polymorphisms within the human TLR2 gene have been reported in non-coding and coding sequences.
Sabine, Merx, Michael, Neumaier, Hermann, Wagner, Carsten J, Kirschning, Parviz, Ahmad-Nejad   +4 more
openaire   +2 more sources

Clostridium scindens promotes gallstone formation by inducing intrahepatic neutrophil extracellular traps through CXCL1 produced by colonic epithelial cells

Microbial Cell
Cholelithiasis is one of the most common diseases of the biliary system. Neutrophil extracellular traps (NETs) in the liver play an important role in accelerating the formation of gallstones. The upstream mechanism of NETs formation remains unclear.
Wenchao Yao, Yuanhang He, Zhihong Xie, Qiang Wang, Yang Chen, Jingjing Yu, Xuxu Liu, Dongbo Xue, Liyi Wang, Chenjun Hao   +9 more
doaj   +1 more source

TLR2 and TLR4 in Ischemia Reperfusion Injury [PDF]

Mediators of Inflammation, 2010
Ischemia reperfusion (I/R) injury refers to the tissue damage which occurs when blood supply returns to tissue after a period of ischemia and is associated with trauma, stroke, myocardial infarction, and solid organ transplantation. Although the cause of this injury is multifactorial, increasing experimental evidence suggests an important role for the ...
F. Arslan, B. Keogh, P. McGuirk, A. E. Parker   +3 more
openaire   +3 more sources