Results 31 to 40 of about 103,839 (247)
Virulence, 2021 The toll-like receptor (TLR) family comprises both cell-surface and intracellular receptors that recognize different types of pathogen-associated molecular patterns (PAMPs) leading to the production of pro-inflammatory cytokines and subsequent ...
José M. Rojas +7 more
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Медицинская иммунологияTLR2 is an exceptional pattern-recognizing receptor because of its ability to heterodimerise with different types of TLRs, which allows it to recognize a wide range of molecular structures on the surface of pathogens.
S. O. Lukyanova +3 more
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OncoImmunology, 2018 Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk.
Yingxin Yu +5 more
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Virulence, 2021 Surra, one of the most important animal diseases with economic consequences in Asia and South America, is caused by Trypanosoma evansi. However, the mechanism of immune evasion by T. evansi has not been extensively studied.
Ran Wei +7 more
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TLR2 Mediates Immunity to Experimental Cysticercosis [PDF]
International Journal of Biological Sciences, 2011 Information concerning TLR-mediated antigen recognition and regulation of immune responses during helminth infections is scarce. TLR2 is a key molecule required for innate immunity and is involved in the recognition of a wide range of viruses, bacteria, fungi and parasites. Here, we evaluated the role of TLR2 in a Taenia crassiceps cysticercosis model.
José L, Reyes +4 more
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The function of TLR2 during staphylococcal diseases [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 Staphylococcus aureus is a versatile pathogen causing a wide range of infections. It has been a major threat both in hospitals and in the community for decades. S. aureus is a pyogenic bacterium that elicits recruitment of polymorphonuclear leukocytes (neutrophils) to the site of infection.
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TLR2 and TLR4 in Ischemia Reperfusion Injury [PDF]
Mediators of Inflammation, 2010 Ischemia reperfusion (I/R) injury refers to the tissue damage which occurs when blood supply returns to tissue after a period of ischemia and is associated with trauma, stroke, myocardial infarction, and solid organ transplantation. Although the cause of this injury is multifactorial, increasing experimental evidence suggests an important role for the ...
F. Arslan +3 more
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Медицина в КузбассеРаботники предприятий черной металлургии подвергаются воздействию промышленных аэрозолей органической и неорганической природы, что может приводить к нарушению механизмов врожденного иммунитета и увеличению частоты респираторных инфекций.
Татьяна Викторовна Бушуева +5 more
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Evaluation of TlR2 and 4 in Chronic Periodontitis
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2016 Periodontal disease is the major cause of adult tooth loss and is commonly characterized by a chronic inflammation caused by infection due to oral bacteria. Members of Toll-Like Receptor (TLR) family recognize conserved microbial structures, such as bacterial lipopolysaccharides and activate signalling pathways that result in immune responses against ...
Paavai Ilango +4 more
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PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source