Results 41 to 50 of about 19,241 (251)

Assessment of laboratory indicators of inflammatory, infection and indicators of subclinical atherosclerosis in patients with systemic lupus erythematosus

Научно-практическая ревматология
The aim of the study was to reveal the relationship between the activity of inflammation, the infectious component, platelet function and dyslipidemia, in the development of subclinical atherosclerosis in patients with systemic lupus erythematosus (SLE ...
A. V. Arshinov, N. Yu. Levshin, I. G. Maslova, A. A. Baranov, V. I. Emanuylov   +4 more
doaj   +1 more source

Hemagglutinin protein of Peste des Petits Ruminants virus (PPRV) activates the innate immune response via Toll-like receptor 2 signaling

Virulence, 2021
The toll-like receptor (TLR) family comprises both cell-surface and intracellular receptors that recognize different types of pathogen-associated molecular patterns (PAMPs) leading to the production of pro-inflammatory cytokines and subsequent ...
José M. Rojas, Elena Pascual, Sean R. Wattegedera, Miguel Avia, César Santiago, Verónica Martín, Gary Entrican, Noemí Sevilla   +7 more
doaj   +1 more source

Association of TLR2 Arg753Gln gene polymorphism with its expression level in nonagenarians with frailty

Медицинская иммунология
TLR2 is an exceptional pattern-recognizing receptor because of its ability to heterodimerise with different types of TLRs, which allows it to recognize a wide range of molecular structures on the surface of pathogens.
S. O. Lukyanova, O. V. Artemieva, E. D. Nasaeva, L. V. Gankovskaya   +3 more
doaj   +1 more source

Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models

OncoImmunology, 2018
Chronic inflammation drives the development of colorectal cancer (CRC), where tumor-infiltrating immune cells interact with cancer cells in a dynamic crosstalk.
Yingxin Yu, Bart Blokhuis, Yvonne Derks, Sangeeta Kumari, Johan Garssen, Frank Redegeld   +5 more
doaj   +1 more source

Trypanosoma evansi evades host innate immunity by releasing extracellular vesicles to activate TLR2-AKT signaling pathway

Virulence, 2021
Surra, one of the most important animal diseases with economic consequences in Asia and South America, is caused by Trypanosoma evansi. However, the mechanism of immune evasion by T. evansi has not been extensively studied.
Ran Wei, Xin Li, Xiaocen Wang, Nan Zhang, Yuru Wang, Xichen Zhang, Pengtao Gong, Jianhua Li   +7 more
doaj   +1 more source

TLR2-FcgR Synergy

, 2018
Data supporting PLoS ONE manuscript on TLR2-FcgR ...
Danielle Hunt (322731), James Drake (5463110), Lisa A. Drake (5463209)   +2 more
core   +1 more source

Trypanosomiasis-induced Th17-like immune responses in carp [PDF]

, 2010
Background - In mammalian vertebrates, the cytokine interleukin (IL)-12 consists of a heterodimer between p35 and p40 subunits whereas interleukin-23 is formed by a heterodimer between p19 and p40 subunits.
B M Lidy Verburg-van Kemenade, Verburg-van Kemenade, B.M.L., Chadzinska Magdalena, Wiegertjes Geert F., Chadzinska, M.K., Huub F. J. Savelkoul, Scheer Marleen, Savelkoul, H.F.J., Scheer, M.H., Geert F Wiegertjes, Savelkoul Huub F. J., Bird, S., Maria J. S. L. Pontes, Ribeiro, Carla M. S., B. M. Lidy Verburg-van Kemenade, Wiegertjes, G.F., Savelkoul, Huub F. J., Carla M S Ribeiro, Scheer, Marleen, Marleen Scheer, Verburg-van Kemenade B. M. Lidy, Steve Bird, Maria J S L Pontes, Huub F J Savelkoul, Pontes, Maria J. S. L., Verburg-van Kemenade, B. M. Lidy, Ribeiro, C.M.S., Wiegertjes, Geert F., Bird Steve, Magdalena Chadzinska, Carla M. S. Ribeiro, Pontes, M.J.S.L., Ribeiro Carla M. S., Chadzinska, Magdalena, Pontes Maria J. S. L., Bird, Steve, Geert F. Wiegertjes   +36 more
core   +2 more sources

Enhanced TLR2 responses in multiple sclerosis [PDF]

Clinical and Experimental Immunology, 2018
Summary The roles of the microbiome and innate immunity in the pathogenesis of multiple sclerosis (MS) remain unclear. We have previously documented abnormally low levels of a microbiome-derived Toll-like receptor (TLR)2-stimulating bacterial lipid in the blood of MS patients and postulated that this is indicative of a deficiency in the ...
M Fujiwara, E J Anstadt, B Flynn, K Morse, C Ng, P Paczkowski, J Zhou, S Mackay, N Wasko, F Nichols, R B Clark   +10 more
openaire   +2 more sources

АССОЦИАЦИЯ ПОЛИМОРФИЗМОВ ГЕНОВ TLR2, TLR4 И TLR6 С КОЛОНИЗАЦИЕЙ STREPTOCOCCUS PNEUMONIAE У РАБОТНИКОВ МЕТАЛЛУРГИЧЕСКОГО ПРОИЗВОДСТВА

Медицина в Кузбассе
Работники предприятий черной металлургии подвергаются воздействию промышленных аэрозолей органической и неорганической природы, что может приводить к нарушению механизмов врожденного иммунитета и увеличению частоты респираторных инфекций.
Татьяна Викторовна Бушуева, Елизавета Павловна Артёменко, Наталья Алексеевна Рослая, Юлия Витальевна Грибова, Алла Константиновна Лабзова, Владимир Борисович Гурвич   +5 more
doaj   +1 more source

Core residues of TLR2 TIR domain critical for TLR2-VCL interaction.

, 2023
Core residues of TLR2 TIR domain critical for TLR2-VCL interaction.
Jeba Gnanasekaran (15195368), Luba Eli-Berchoer (422858), Gabriel Nussbaum (269899), Fabian Glaser (9878), Karthikeyan Pandi (15195362), Sarah Angabo (15195365), Hasnaa Makkawi (15195371)   +6 more
core   +1 more source