Results 21 to 30 of about 45,202 (234)
Methylation Regulation of TLR3 on Immune Parameters in Lung Adenocarcinoma
Frontiers in Oncology, 2021 This study aims to analyze the methylation regulation of TLR3 in lung adenocarcinoma (LUAD) and to explore the association of TLR3 expression with immune microenvironment.
Ang Li +7 more
doaj +1 more source
HLA-A*0206 with TLR3 polymorphisms exerts more than additive effects in Stevens-Johnson syndrome with severe ocular surface complications. [PDF]
PLoS ONE, 2012 BACKGROUND: Stevens-Johnson syndrome (SJS) is an acute inflammatory vesiculobullous reaction of the skin and mucosa, often including the ocular surface, and toxic epidermal necrolysis (TEN) occurs with its progression.
Mayumi Ueta +6 more
doaj +1 more source
Microcefalia por Zika un problema latente: Reporte de Caso y Aspectos Moleculares
Infectio, 2020 We present the case of a 20-day-old patient from Cartagena (Bolívar), hospitalized for presenting a 6-day fever associated with respiratory symptoms with normal neurological evaluation. The obstetric ultrasound showed a microcephaly with a percentile of
Oscar Patiño
doaj +1 more source
Roles of Toll-Like Receptor 3 in Human Tumors
Frontiers in Immunology, 2021 Toll-like receptor 3 (TLR3) is an important member of the TLR family, which is an important group of pathogen-associated molecular patterns. TLR3 can recognize double-stranded RNA and induce activation of NF-κB and the production of type I interferons ...
Xin Zheng, Song Li, Hui Yang
doaj +1 more source
Both MicroRNA-155 and Virus-Encoded MiR-155 Ortholog Regulate TLR3 Expression. [PDF]
PLoS ONE, 2015 MicroRNA-155 (miR-155) has been as an important controller of TLR3 signalling. However, the interactions between miR-155 and TLR3 are poorly understood. Here, we focused on the regulation of the relationship between miR-155 and TLR3.
Xuming Hu +5 more
doaj +1 more source
Journal of Virology, 2021 Zika virus (ZIKV) has a pronounced neurotropism, and infections with this virus can cause serious neurological disorders, most notably microcephaly and Guillain-Barré syndrome.
Agnieszka Płóciennikowska +8 more
semanticscholar +1 more source
Acta Pharmaceutica Sinica B, 2022 Toll-like receptor 3 (TLR3), as an important pattern recognition receptor (PRR), dominates the innate and adaptive immunity regulating many acute and chronic inflammatory diseases.
Xiaohong Cen +9 more
doaj +1 more source
Regulation of TLR3 Activation by S100A9 [PDF]
The Journal of Immunology, 2015 Abstract Recognition of viral dsRNA by endosomal TLR3 activates innate immune response during virus infection. Trafficking of TLR3 to the endolysosomal compartment arising from fusion of late endosome (LE) with lysosome is required for recognition and detection of pathogen associated molecular patterns, which results in activation of the
Su-Yu, Tsai +11 more
openaire +2 more sources
Bufalin Inhibits Cytokine Storm by Regulating TLR4/TLR3 Signaling Pathway. [PDF]
Immun Inflamm DisABSTRACT Background Bufalin is one main component of the dried venom from Bufo gargarizans Cantor, which has anti‐tumor, cardiotonic, anti‐inflammatory and other physiological activities. However, in recent years, researchers have mainly paid attention to its anti‐tumor effect and neglected its anti‐inflammatory effect.
Liu X +11 more
europepmc +2 more sources
The zinc-finger protein ZFYVE1 modulates TLR3-mediated signaling by facilitating TLR3 ligand binding [PDF]
Cellular & Molecular Immunology, 2019 Recognition of viral dsRNA by Toll-like receptor 3 (TLR3) leads to the induction of downstream antiviral effectors and the innate antiviral immune response. Here, we identified the zinc-finger FYVE domain-containing protein ZFYVE1, a guanylate-binding protein (GBP), as a positive regulator of TLR3-mediated signaling.
Xuan Zhong +7 more
openaire +2 more sources