Results 1 to 10 of about 131,931 (297)
TLR4: the fall guy in sepsis? [PDF]
Cell Stress, 2020 Sepsis and its impact on human health can be traced back to 1000 BC and continues to be a major health burden today. It causes about 11 million deaths world-wide of which, more than a third are due to neonatal sepsis.
Joseph Menassa +3 more
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Effects of Escherichia coli lipopolysaccharide on innate immunity: The expression profile of TLR4 and CD14 genes in rat's liver [PDF]
Open Veterinary Journal, 2021 Background: Bacterial Endotoxin (lipopolysaccharide) is essential for bacterial virulence, as it has a biphasic effect which is either harmful and leads to aseptic shock and death or assists the body defense mechanisms as it stimulates B-cells activation.
Ammar M. Al-Aalim +2 more
doaj +1 more source
Polymorphism study of TLR4 gene in crossbred cattle of Kerala [PDF]
Journal of Veterinary and Animal Sciences, 2023 The present study was conducted to identify single nucleotide variations in exon 3 region of the bovine Toll-Like Receptor gene (TLR4) associated with somatic cell score (SCS) in crossbred cattle of Kerala using polymerase chain reaction-single ...
G. Chishi Kiyevi +5 more
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The role of Toll-like receptors in chemoradiotherapy-induced gastrointestinal mucositis
口腔疾病防治, 2021 Mucositis is a common gastrointestinal complication in cancer patients undergoing chemoradiotherapy, including oral mucositis and gastrointestinal mucositis, with clinical manifestations of oral ulcers, vomiting, diarrhea and pain that seriously reduce ...
JI Ling +3 more
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Virulence, 2021 Whole-cell vaccines against Gram-negative bacteria commonly display high reactogenicity caused by the endotoxic activity of lipopolysaccharide (LPS), one of the major components of the bacterial outer membrane. Underacylation of the lipid A moiety of LPS
Jesús Pérez-Ortega +7 more
doaj +1 more source
Pathogens, 2020 Bovine mastitis is the inflammatory reaction of the mammary gland and is commonly caused by bacterial infections in high-yielding dairy cows. The detailed investigation of the immunotranscriptomic response of bovine mammary epithelial (BME) cells to ...
Md. Aminul Islam +12 more
doaj +1 more source
Inflammatory signaling of HMGB1 in depressive disorder
Stress and Brain, 2023 Background:Depressive disorder is a common disease characterized by depressed mood and loss of pleasure, which often brings a great grief to patients and a huge burden to the society.
Qian Jiang +4 more
doaj +1 more source
Flower extract of Caragana sinica. ameliorates Dss-induced ulcerative colitis by affecting TLR4/NF-κB and TLR4/MAPK signaling pathway in a mouse model [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): This study aimed to find out the protective effects and preliminary mechanisms of the flower extract of Caragana sinica (FEC) on dextran sulfate sodium salt (DSS)-induced colitis.Materials and Methods: The ulcerative colitis models of mice ...
Ting Li +9 more
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The Prophylactic Use of Bovine Colostrum in a Murine Model of TNBS-Induced Colitis
Animals, 2020 This study investigated the effects of a short-term administration of bovine colostrum (BC) in a TNBS model of induced colitis. Colitis was induced by TNBS treatment after seven days of BC (BC group, n = 12) or saline (control group, n = 12 ...
Laura Menchetti +13 more
doaj +1 more source
The Defensive Action of LYRM03 on LPS-Induced Acute Lung Injury by NF-κB/TLR4/NLRP3 Signals
Journal of Investigative Surgery, 2021 The aim of the current investigation was to study the role of 3-amino-2-hydroxy-4-phenyl-valyl-isoleucine (LYRM03) in lipopolysaccharide (LPS)-induced acute lung injury (ALI) and investigate its potential pathogenesis.
Bin Wang +4 more
doaj +1 more source