Results 1 to 10 of about 274,305 (384)

Microglia/macrophage-specific deletion of TLR-4 protects against neural effects of diet-induced obesity in a sexually dimorphic manner. [PDF]

J Neuroinflammation
Liu J, Zaidi A, Pike CJ.
europepmc   +1 more source

TLR4-Based Immunotherapeutics in Cancer: A Review of the Achievements and Shortcomings.

Molecular Pharmaceutics, 2018
Toll-like Receptor 4 (TLR4) agonists have had a long journey in the field of cancer immunotherapy. Nevertheless, despite the remarkable number of the TLR4 ligands that have gone through various preclinical and clinical stages, only two (Bacillus Calmette-
Maryam A. Shetab Boushehri, A. Lamprecht
semanticscholar   +1 more source

Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.

Science, 1998
A. Poltorak, Xiaolong He, I. Smirnova, Mu-ya Liu, C. Huffel, Xin Du, D. Birdwell, Erica Alejos, Maria Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, Betsy Layton, B. Beutler   +13 more
semanticscholar   +1 more source

LPS/TLR4 signal transduction pathway.

Cytokine, 2008
Yong-Chen Lu, W. Yeh, P. Ohashi
semanticscholar   +1 more source

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

Nature, 2009
B. Park, D. Song, Ho Min Kim, Byong-Seok Choi, Hayyoung Lee, Jie-Oh Lee   +5 more
semanticscholar   +1 more source

Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood

Nature Medicine, 2007
Stephen R. Clark, Adrienne C. Ma, Samantha A. Tavener, B. McDonald, Zahra Goodarzi, M. Kelly, K. Patel, S. Chakrabarti, Erin F. McAvoy, G. Sinclair, Elizabeth Keys, E. Allen-Vercoe, R. Devinney, C. Doig, F. Green, P. Kubes   +15 more
semanticscholar   +1 more source

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

Nature Genetics, 2000
N. Arbour, E. Lorenz, B. Schutte, J. Zabner, J. Kline, Michael P. Jones, K. Frees, J. L. Watt, D. Schwartz   +8 more
semanticscholar   +1 more source

Noncanonical Inflammasome Activation by Intracellular LPS Independent of TLR4

Science, 2013
N. Kayagaki, M. Wong, Irma B. Stowe, S. R. Ramani, Lino C. Gonzalez, Sachiko Akashi-Takamura, K. Miyake, Juan Zhang, Wyne P. Lee, Artur Muszyński, L. S. Forsberg, R. Carlson, V. Dixit   +12 more
semanticscholar   +1 more source

Resistin facilitates breast cancer progression via TLR4-mediated induction of mesenchymal phenotypes and stemness properties

Oncogene, 2018
C-H Wang, P.-J. Wang, Y. Hsieh, S. Lo, Y-C Lee, Y-C Chen, Chun-Hao Tsai, Wen‐Chin Chiu, S. Hu, C.-W. Lu, Y.-F. Yang, Ching-Chi Chiu, F. Ou-Yang, Y-M Wang, M. Hou, S. Yuan   +15 more
semanticscholar   +1 more source