Results 231 to 240 of about 175,490 (344)

Exploring the Role of Acrylamide in Food Allergy via Dendritic Cell‐Dependent Th2 Immune Responses

Food Frontiers, EarlyView.
Acrylamide may disrupt immune tolerance as a foodborne immunotoxicant, priming allergic inflammatory susceptibility through DC‐dependent Th2/Th17 polarization, TLR4/NF‐κB signaling amplification, and IL‐10 production suppression. ABSTRACT Acrylamide (AA), a prevalent food processing contaminant with recognized multi‐organ toxicity, has an unexplored ...
Xue Feng, Jiamin Chen, Zhencong Yang, Philippe Madjirebaye, Zhoujin Xu, Li Yan, Yuting Fan, Xiaoliang Shu, Xuli Wu   +8 more
wiley   +1 more source

Evaluation of the Percentage of Monocyte Subpopulations with TLR2 and TLR4 Expression About Selected Skin Functional Parameters in Patients with Acne Vulgaris-Cross-Sectional Study. [PDF]

J Clin Med
Firlej E, Grzegorzewska W, Jastrzębska-Pawłowska K, Janiszewska M, Gąbka-Flis I, Makarska-Białokoz M, Roliński J, Bartosińska J.   +7 more
europepmc   +1 more source

ENDOTOXIN (LPS) STIMULATES IN VIVO EXPRESSION OF INFLAMMATORY CYTOKINES IN SKELETAL MUSCLE VIA TLR4.

, 2002
Charles H. Lang, Christine Silvis, Gerald J. Nystrom, R A Frost   +3 more
openalex   +1 more source

Specific Engagement of TLR4 or TLR3 Does Not Lead to IFN-β-Mediated Innate Signal Amplification and STAT1 Phosphorylation in Resident Murine Alveolar Macrophages [PDF]

, 2004
Antonello Punturieri, Rebecca S. Alviani, Timothy Polak, Phil Copper, Joanne Sonstein, Jeffrey L. Curtis   +5 more
openalex   +1 more source

SP696SOLUBLE TLR4 IN HEMODIALYSIS PATIENTS [PDF]

Nephrology Dialysis Transplantation, 2017
Elena Caramella, Giacomo Garibotto, Maria Antonietta Grignano, Marilena Gregorini, Marta Calatroni, Edoardo La Porta, Alessandro Avella, Yuri Battaglia, Carmelo Libetta, Francesca Ansaldo, Teresa Rampino, Samantha Milanesi, Pasquale Esposito, Daniela Verzola   +13 more
openaire   +2 more sources

C9orf72 Repeat Expansion Induces Metabolic Dysfunction in Human iPSC‐Derived Microglia and Modulates Glial‐Neuronal Crosstalk

Glia, EarlyView.
C9orf72 microglia display heightened glycolysis and oxidative stress, driving astrocytic reprogramming that impacts motor neurons. iPSC tricultures uncover key glial–neuronal interactions in C9orf72 pathology. ABSTRACT The C9orf72 hexanucleotide repeat expansion mutation is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and ...
Marika Mearelli, Insa Hirschberg, Christin Weissleder, Carmela Giachino, María José Pérez, Malvina Dubroux, Francesca Provenzano, Mafalda Rizzuti, Linda Ottoboni, Udit Sheth, Tania F. Gendron, Stefania Corti, Michela Deleidi   +12 more
wiley   +1 more source

The relationship between the expression of serum PTEN and TLR4 and the severity and prognosis of neonatal sepsis. [PDF]

Ital J Pediatr
Lu J, Wang J, Qi Q, Du M.
europepmc   +1 more source

TLR4 mediates LPS-induced HO-1 expression in mouse liver: Role of TNF-α and IL-1β

, 2003
Yong Song
openalex   +1 more source

Altered Inflammatory Signature in a C9ORF72‐ALS iPSC‐Derived Motor Neuron and Microglia Coculture Model

Glia, EarlyView.
Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao, Jessica L. Brothwood, Harpreet Saini, Gregory A. O'Sullivan, Carla F. Bento, James M. McCarthy, Nicola G. Wallis, Elena Di Daniel, Brent Graham, Daniel M. Tams   +9 more
wiley   +1 more source

An immunoinformatics-based designed multi-epitope candidate vaccine against Mycoplasma pneumoniae. [PDF]

BMC Microbiol
Shahbazi B, Mottaghi-Dastjerdi N, Soltany-Rezaee-Rad M, Ahmadi K.   +3 more
europepmc   +1 more source