Results 61 to 70 of about 262,724 (386)
Interaction of Opioids with TLR4—Mechanisms and Ramifications [PDF]
Cancers, 2021 The innate immune receptor toll-like receptor 4 (TLR4) is known as a sensor for the gram-negative bacterial cell wall component lipopolysaccharide (LPS). TLR4 activation leads to a strong pro-inflammatory response in macrophages; however, it is also recognised to play a key role in cancer.
Mai Mahmoud Gabr +6 more
openaire +3 more sources
Journal of Veterinary Research, 2021 Inflammation is one of the main causes of impaired health in livestock and some of its processes weaken animal productivity and impact human health. The present study was conducted to evaluate the effect of echinacea extract (cichoric acid – CA) on yak ...
Xue Cai-hua +8 more
doaj +1 more source
Food & Nutrition Research, 2022 Background: Inflammatory bowel diseases are characterized by the alterations of the mucosa and gastrointestinal physiology, and the core of these alterations is endothelial cells.
Hui-Xin Zhang +3 more
doaj +1 more source
Targeting danger molecules in tendinopathy: the HMGB1/TLR4 axis [PDF]
, 2017 Objectives: To seek evidence of the danger molecule, high-mobility group protein B1 (HMGB1) expression in human tendinopathy and thereafter, to explore mechanisms where HMGB1 may regulate inflammatory mediators and matrix regulation in human tendinopathy.
Akbar, Moeed +10 more
core +1 more source
Frontiers in Immunology, 2020 The innate immune response to lipopolysaccharide is essential for host defense against Gram-negative bacteria. In response to bacterial infection, the TLR4/MD-2 complex that is expressed on the surface of macrophages, monocytes, dendritic, and epithelial
A. Zamyatina, H. Heine
semanticscholar +1 more source
مقایسه بیان ژن های لاکتوفرین و TLR4 در سلول های سوماتیک شیر گاو هلشتاین، بومی گیلان و آمیخته‌های حاصل از آنها [PDF]
تحقیقات تولیدات دامی, 2016 هدف تحقیق حاضر مقایسه بیان ژنهای لاکتوفرین و TLR4 در سلولهای سوماتیک شیر گاو و بررسی تفاوتهای ژنتیکی و آمیختهگری بر بیان ژنهای سیستم ایمنی و همچنین اثرات ورم پستان بر بیان ژنهای مذکور است.
پری ناز رضوانی +3 more
doaj
Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence [PDF]
, 2005 Viral immune evasion strategies target key aspects of the host antiviral response. Recently, it has been recognized that Toll-like receptors (TLRs) have a role in innate defense against viruses.
Bartlett, Nathan W +8 more
core +2 more sources
TLR4 and HMGB1: partners in crime? [PDF]
Kidney International, 2011 Chen et al. confirmed the role of Toll-like receptor 4 (TLR4) in ischemic kidney injury using mice harboring spontaneous disabling mutations of the receptor and generated chimeras between TLR4-/- and TLR4+/+ mice. The major findings demonstrate the necessity of TLR4 in leukocytes, as well as in epithelial and endothelial cells, for the full-blown ...
openaire +3 more sources
Oxidative Medicine and Cellular Longevity, 2020 Background It is widely accepted that inflammation may contribute to cognitive impairment in patients with vascular dementia (VD). Our prior clinical researches have reported that acupuncture can alleviate cognitive function in VD, but the underlying ...
Lu Wang +8 more
semanticscholar +1 more source
TLR4 rs1927914 polymorphism contributes to serum TLR4 levels in patients with aortic aneurysm
Experimental and Molecular Pathology, 2021 Toll-like receptor 4 (TLR4) is a crucial regulator of inflammatory reactions and vascular remodeling. Elevated TLR4 expression has been proved to be correlated with an increased risk of aortic aneurysm (AA). This study aimed to explore the influence of TLR4 gene polymorphisms on TLR4 expression levels and its probable functional significance in AA ...
Chunyan Ma +5 more
openaire +3 more sources