Results 11 to 20 of about 9,070 (169)

A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1 [PDF]

Mobile DNA, 2021
Background Toll-like receptors (TLRs) play important roles in building innate immune and inducing adaptive immune responses. Associations of the TLR genes polymorphisms with disease susceptibility, which are the basis of molecular breeding for disease ...
XiaoYan Wang, Zixuan Chen, Eduard Murani, Enrico D’Alessandro, Yalong An, Cai Chen, Kui Li, Grazia Galeano, Klaus Wimmers, Chengyi Song   +9 more
doaj   +3 more sources

Gene conversion limits divergence of mammalian TLR1 and TLR6 [PDF]

BMC Evolutionary Biology, 2007
Background Toll-like receptors (TLR) recognize pathogen-associated molecular patterns and are important mediators of the innate immune system. TLR1 and TLR6 are paralogs and located in tandem on the same chromosome in mammals. They form heterodimers with
Dunoyer-Geindre Sylvie, Liu Jia, Satta Nathalie, Kruithof Egbert KO, Fish Richard J   +4 more
doaj   +4 more sources

CopE and TLR6 RNAi-mediated tomato resistance to western flower thrips

Journal of Integrative Agriculture, 2023
The western flower thrips (WFT; Frankliniella occidentalis) is a mesophyll cell feeder that damages many crops. Management of WFT is complex due to factors such as high fecundity, short reproduction time, ability to feed on a broad range of host plants ...
Jelli VENKATESH, Sung Jin KIM, Muhammad Irfan SIDDIQUE, Ju Hyeon KIM, Si Hyeock LEE, Byoung-Cheorl KANG   +5 more
doaj   +2 more sources

An 192 bp ERV Insertion in the First Intron of TLR6 Acts as an Enhancer to Increase TLR6 and TLR1 Expression [PDF]

, 2020
Abstract BackgroundToll-like receptors (TLRs) play important roles in building innate immune and inducing adaptive immune responses. Associations of the TLR gene polymorphisms with diseases susceptibility, which are the basis of molecular breeding for disease resistant animals, have been reported extensively.
xiaoyan wang, Zixuan Chen, Eduard Murani, Enrico D'alessandro, Yalong An, Cai Chen, Kui Li, Grazia Galeano, Klaus Wimmers, Chengyi Song   +9 more
openaire   +4 more sources

BacSp222 bacteriocin as a novel ligand for TLR2/TLR6 heterodimer

Inflammation Research, 2023
Abstract Objective and design BacSp222 bacteriocin is a bactericidal and proinflammatory peptide stimulating immune cells to produce selected cytokines and NO in NF-ĸB dependent manner. This study aims to identify the receptor which mediates this activity.
Śmiałek-Bartyzel, Justyna, Bzowska, Monika, Mężyk-Kopeć, Renata, Kwissa, Marcin, Mak, Paweł   +4 more
openaire   +3 more sources

Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis

HGG Advances, 2022
Summary: Human genetic diversity can have profound effects on health outcomes upon exposure to infectious agents. For infections with Chlamydia trachomatis (C.
Alyson B. Barnes, Rachel M. Keener, Benjamin H. Schott, Liuyang Wang, Raphael H. Valdivia, Dennis C. Ko   +5 more
doaj   +1 more source

TLR6 Modulates First Trimester Trophoblast Responses to Peptidoglycan [PDF]

The Journal of Immunology, 2008
Abstract Intrauterine bacterial infections are a well-established cause of pregnancy complications. One key observation in a number of abnormal pregnancies is that placental apoptosis is significantly elevated. First trimester trophoblast cells are known to express TLR1 and TLR2 and to undergo apoptosis following exposure to Gram ...
Vikki M, Abrahams, Paulomi B, Aldo, Shaun P, Murphy, Irene, Visintin, Kaori, Koga, Gabriella, Wilson, Roberto, Romero, Surendra, Sharma, Gil, Mor   +8 more
openaire   +2 more sources

Hypoxia inducible factor (HIF)-1 coordinates induction of Toll-like receptors TLR2 and TLR6 during hypoxia. [PDF]

PLoS ONE, 2007
During acute infection and inflammation, dramatic shifts in tissue metabolism are typical, thereby resulting in profound tissue hypoxia. Therefore, we pursued the hypothesis, that tissue hypoxia may influence innate immune responses by transcriptional ...
Johannes Kuhlicke, Julia S Frick, Julio C Morote-Garcia, Peter Rosenberger, Holger K Eltzschig   +4 more
doaj   +1 more source

Aberrant DNA methylation of the toll-like receptors 2 and 6 genes in patients with obstructive sleep apnea.

PLoS ONE, 2020
Obstructive sleep apnea (OSA) is a syndrome leading to chronic intermittent hypoxia, and the up-regulation of toll-like receptors (TLR) 2 and 6 on peripheral blood cells has been reported.
Kuo-Tung Huang, Yung-Che Chen, Chia-Cheng Tseng, Huang-Chih Chang, Mao-Chang Su, Ting-Ya Wang, Yong-Yong Lin, Yi-Xin Zheng, Jen-Chieh Chang, Chien-Hung Chin, Chang-Chun Hsiao, Meng-Chih Lin   +11 more
doaj   +1 more source

Role of TLR1 and TLR6 in the host defense against disseminated candidiasis [PDF]

FEMS Immunology & Medical Microbiology, 2008
Toll-like receptor-1 (TLR1) and TLR6 are receptors of the TLR family that form heterodimers with TLR2. The role of TLR1 and TLR6 for the recognition of the fungal pathogen Candida albicans was investigated. TLR1 is not involved in the recognition of C.
Netea, M.G., Veerdonk, F.L. van de, Verschueren, I., Meer, J.W.M. van der, Kullberg, B.J.   +4 more
openaire   +3 more sources