Mushroom lectin overcomes hepatitis B virus tolerance via TLR6 signaling [PDF]
Scientific Reports, 2017 Currently, chronic hepatitis B virus (HBV) infection remains a serious public health problem in the world. Recombinant HBV vaccine, as a preventive strategy against HBV infection, generates high antibody level, but it is not effective to activate innate ...
Meina He +4 more
semanticscholar +4 more sources
NFKB1 genetic variation and allergic rhinitis susceptibility: a study in the Chinese Han population [PDF]
Scientific ReportsAllergic rhinitis (AR), a highly prevalent inflammatory disorder of the upper respiratory tract, demonstrates strong genetic determinants. TLR6 and NFKB1 variants were genotyped to assess the associations with AR susceptibility. Blood samples from 992 AR
Haiying Wang +5 more
doaj +2 more sources
Association of toll like receptors polymorphism (<i>TLR</i>1-rs4833095, <i>TLR</i>1-rs5743611, <i>TLR</i>6-rs5743810, <i>TLR</i>6-rs5743809, <i>TLR</i>4-rs4986790, <i>TLR</i>4-rs4986791, <i>TLR</i>9 rs187084) with clinical outcome of malaria among children in Ibadan, Southwest Nigeria. [PDF]
Pathog Glob HealthDifferent genetic polymorphisms, particularly in the erythrocyte receptors and immune response-related genes, have been implicated in the development of malaria. With the first immune response to Plasmodium falciparum related to the activity of toll-like
Bamikole OJ +4 more
europepmc +2 more sources
International Journal of Molecular Sciences, 2016 Current evidence suggests that gut dysbiosis drives obesity and non-alcoholic fatty liver disease (NAFLD) pathogenesis. Toll-like receptor 2 (TLR2) and TLR6 specifically recognize components of Gram-positive bacteria.
Paula Iruzubieta +2 more
exaly +2 more sources
The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6. [PDF]
Veterinary Research, 2013 TLR2 recognises bacterial lipopeptides and lipoteichoic acid, and forms heterodimers with TLR1 or TLR6. TLR2 is relatively well characterised in mice and humans, with published crystal structures of human TLR2/1/Pam3CSK4 and murine TLR2/6/Pam2CSK4 ...
Bryant, Clare Elizabeth +3 more
core +5 more sources
Frontiers in Pharmacology, 2018 Arctigenin (ARG), one of the most active ingredients abstracted from seeds of Arctium lappa L., has been proved to exert promising biological activities such as immunomodulatory, anti-viral, and anti-cancer etc.
Zheng Lu +11 more
doaj +2 more sources
TLR6 Gene Polymorphism, Sequence Analysis, and Phylogenetic Tree in Susscrofa
THE INDIAN JOURNAL OF VETERINARY SCIENCES AND BIOTECHNOLOGY, 2017 TLRs (Toll like receptors) gene have a very important role in early defense against invading pathogens, still we do not have sufficient literature available about them specially TLR6 gene in swine.
N. Kumari, L. B. Singh
semanticscholar +2 more sources
7α-Hydroxycholesterol Elicits TLR6-Mediated Expression of IL-23 in Monocytic Cells [PDF]
Biomolecules & Therapeutics, 2015 We investigated the question of whether 7-oxygenated cholesterol derivatives could affect inflammatory and/or immune responses in atherosclerosis by examining their effects on expression of IL-23 in monocytic cells.
H. Seo +4 more
semanticscholar +3 more sources
Revista Facultad Nacional de Agronomía Medellín, 2017 Specialized dairy systems are one of the most important lines in the agricultural sector in Colombia and the world. Currently there are strategies, both of environmental management and animal breeding, seeking to optimize the production.
Juan Pablo Arismendy Morales +2 more
doaj +2 more sources
Hepatocyte Toll‐like receptors contribute to the hepcidin inflammatory response to pathogens and pathogen‐derived ligands [PDF]
HemaSphereIron restriction is a critical pathomechanism underlying the Anemia of Inflammation and an innate immune response limiting the replication of extracellular pathogens.
Katharina Bonitz +9 more
doaj +2 more sources