Results 41 to 50 of about 10,412 (198)
Association of TLR2 and TLR6 gene polymorphism with Trichomoniasis vaginalis Infection
Advancements in Life Sciences, 2023 Background: Toll-like receptors (TLR2 and TLR6) are a group of receptors that play a crucial role in the innate immune response and recognition of T. vaginalis. Single nucleotide polymorphisms (SNPs) in TLRs were manifested as important determinant affecting the susceptibility to trichomoniasis. This study aims to examine the impact of rs5743708 SNP in
Zainab Waddah Kermasha +2 more
openaire +1 more source
PLoS ONE, 2017 Kawasaki disease (KD) is the most common acquired pediatric heart disease. We analyzed Whole Genome Sequences (WGS) from a 6-member African American family in which KD affected two of four children.
Jihoon Kim +14 more
doaj +1 more source
Contribution of toll-like receptor 2 and nicotinamide adenine dinucleotide phosphate oxidase to the trimethylamine N-oxide-induced inflammatory reactions in U937-derived macrophages [PDF]
ARYA Atherosclerosis, 2021 BACKGROUND: Trimethylamine N-oxide (TMAO) is emerging as a new generation of metabolites related to the activation of inflammatory reactions in the macrophages during atherosclerosis.
Abbas Ahmadi +4 more
doaj +1 more source
Toll-like receptor 6 inhibits colorectal cancer progression by suppressing NF-κB signaling
HeliyonBackground: Toll-like receptors (TLRs) are implicated in the pathogenesis and progression of inflammation-associated cancers, except their role in regulating innate immunity.
Lina Ma +9 more
doaj +1 more source
Polymorphism of genes of Toll-like receptors as a potential factor of predisposition to tuberculosis
Туберкулез и болезни лёгких, 2018 The objective of the study: to detect genotypes and frequency of gene alleles of Toll-receptors (Arg753Gln – for TLR2; Phe412Leu – for TLR3; Asp299Gly – for TLR4; Ser249Pro – for TLR6) among respiratory tuberculosis patients in Zabaykalsky Kray.Subjects ...
E. S. Bogodukhovа, E. E. Bаyke
doaj +1 more source
TLR6 was involved in NS3 mediated microglial activation.
, 2015 Microglia was exposed to 20 ng/ml of NS3 for different time points and cells were stained for TLR6 protein expression. (A-B) Flow cytometry results indicates that TLR6 expression was significantly high from 1 hr to 3 hr time point.
Ayilam Ramachandran Rajalakshmy (737648) +2 more
core +1 more source
MicroRNA-494-3p alleviates inflammatory response in sepsis by targeting TLR6.
European review for medical and pharmacological sciences, 2019 To clarify whether microRNA-494-3p could exert an anti-inflammation effect by suppressing the expression of toll-like receptor 6 (TLR6), thus inhibiting the development of sepsis.Plasma levels of microRNA-494-3p and TLR6 in sepsis patients and healthy controls were determined by quantitative real-time polymerase chain reaction (qRT-PCR).
Wang, H.-F. +4 more
openaire +2 more sources
Surface-Expressed TLR6 Participates in the Recognition of Diacylated Lipopeptide and Peptidoglycan in Human Cells [PDF]
The Journal of Immunology, 2005 Abstract Recognition of microbial components by TLR2 requires cooperation with other TLRs. TLR6 has been shown to be required for the recognition of diacylated lipoproteins and lipopeptides derived from mycoplasma and to activate the NF-κB signaling cascade in conjunction with TLR2.
Yoshiya, Nakao +7 more
openaire +2 more sources
TLR6 restores PDG-mediated inhibition of trophoblast IL-6 expression.
, 2013 (A) The human first trimester trophoblast cell line, 3A, which lacks TLR6 (TLR6-), was treated with no treatment (NT) or peptidoglycan (PDG) at 80μg/ml for 3-24h, after which total RNA was isolated and IL-6 mRNA measured by qRT-PCR using GAPDH as an ...
Julie A. Potter (470868) +2 more
core +1 more source
, 2017 Positions of the exonic SNVs rs5743809 and rs3522046 on the TLR6 protein diagrammed using NCBI Molecular Modeling database (MMDB). The replaced amino acids (p.Leu194Pro and p.Arg247Lys) are shown in green.
Narayanan Veeraraghavan (13928) +13 more
core +1 more source