Results 61 to 70 of about 10,412 (198)

Monocytes Derived From Human Pluripotent Stem Cells Engineered for Detection of Pyrogens

Cell Proliferation, EarlyView.
In summary, we have developed a monocyte‐based reporter system using hESC‐Mono for interrogating the NF‐κB signalling axis, a central pathway governing pyrogenic responses. Our platform enables rapid and dose‐dependent detection of both endotoxins (LPS) and non‐endotoxins (LTA and Zymosan).
Jingjing Liu, Bingyu Cai, Tingting Gao, Wumei Wei, Liu Wang, Qi Zhou, Wei Li, Jie Hao, Jun Wu   +8 more
wiley   +1 more source

Primer sequences for TLR1, TLR2, TLR4 and TLR6.

, 2014
Primer sequences for TLR1, TLR2, TLR4 and TLR6.
Teske Schoffelen (278687), Annemieke Dinkla (299308), Tom Sprong (278692), Hendrik-I J. Roest (639405), Jacob Post (639406), Johanna M. Rebel (639407), Anne Ammerdorffer (639404), Marcel van Deuren (15650)   +7 more
core   +1 more source

The summarized results of multivariate linear regression and multiple comparisons in DNA methylation levels of TLR2 promoter region, TLR6 gene body, and protein expressions of TLR2 and TLR6 between healthy subjects and patients with severe OSA.

, 2020
The DNA methylation levels over CpG#1, #2, #3, #18, #25, and #28 of TLR2, and CpG#1 and CpG#3 of TLR6 were significant differently between HS and OSA after multivariate linear regression.
Chang-Chun Hsiao (381914), Chia-Cheng Tseng (598324), Huang-Chih Chang (598326), Meng-Chih Lin (162902), Yung-Che Chen (381913), Kuo-Tung Huang (598325), Yong-Yong Lin (4030910), Jen-Chieh Chang (381921), Chien-Hung Chin (4030907), Mao-Chang Su (33430), Ting-Ya Wang (381920), Yi-Xin Zheng (4030904)   +11 more
core   +1 more source

Haplotype Disequilibrium in the TLR Genes of Czech Red Pied Cattle

Diversity, 2023
Hybrid resequencing of the antibacterial innate immune genes coding for toll-like receptors, namely TLR1, TLR2, TLR4, TLR5, and TLR6, using HiSeq and PacBio technologies of pooled population samples of Czech Simmental (Czech Red) cattle allowed us to ...
Kalifa Samaké, Karel Novák
doaj   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Role for MyD88, TLR2 and TLR9 but Not TLR1, TLR4 or TLR6 in Experimental Autoimmune Encephalomyelitis [PDF]

The Journal of Immunology, 2011
Abstract The potential roles of TLRs in the cause and pathogenesis of autoimmune CNS inflammation remain contentious. In this study, we examined the effects of targeted deletions of TLR1, TLR2, TLR4, TLR6, TLR9, and MyD88 on the induction of myelin oligodendrocyte glycoprotein 35–55 (MOG35–55) peptide/CFA/pertussis toxin-induced ...
Miranda-Hernandez, Socorro, Gerlach, Nicole, Fletcher, Julie M., Biros, Erik, Mack, Matthias, Körner, Heinrich, Baxter, Alan G.   +6 more
openaire   +2 more sources

Determination of Genetic Variations of Toll-Like Receptor (TLR) 2, 4, and 6 with Next-Generation Sequencing in Native Cattle Breeds of Anatolia and Holstein Friesian

Diversity, 2016
In recent years, the focus of disease resistance and susceptibility studies in cattle have been on determining patterns in the innate immune response of key proteins, such as Toll-like receptors (TLR).
Nuket Bilgen, Bengi Cinar Kul, Victoria Offord, Dirk Werling, Okan Ertugrul   +4 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

TLR6 variants in African American family with two affected siblings.

, 2017
TLR6 variants in African American family with two affected siblings.
Narayanan Veeraraghavan (13928), Stephen F. Kingsmore (104189), Eric Levy (3713023), Chisato Shimizu (84989), Olivier Harismendy (239761), Hai Yang (1646371), Martin L. Hibberd (167212), Jane C. Burns (268128), Andre M. Ribeiro dos Santos (3713029), Long Truong Hoang (653872), Adriana H. Tremoulet (387274), Jay Flatley (3713026), Lucila Ohno-Machado (3907), Jihoon Kim (10090)   +13 more
core   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source