Results 71 to 80 of about 18,028 (232)

TlR expression profile of human gingival margin-derived stem progenitor cells [PDF]

, 2015
Background: Gingival margin-derived stem/progenitor cells (G-MSCs) show remarkable periodontal regenerative potential in vivo. During regeneration, G-MSCs may interact with their inflammatory environment via toll-likereceptors (TLRs).
Adam-Klages, Sabine, Dörfer, Christof, Fawzy-El-Sayed, Karim, Kabelitz, Dietrich, Mekhemar, Mohamed   +4 more
core   +1 more source

gga-miR-146c Activates TLR6/MyD88/NF-κB Pathway through Targeting MMP16 to Prevent Mycoplasma Gallisepticum (HS Strain) Infection in Chickens

Cells, 2019
Mycoplasma gallisepticum (MG), a pathogen that infects chickens and some other birds, triggers chronic respiratory disease (CRD) in chickens, which is characterized by inflammation. The investigation of microbial pathogenesis would contribute to the deep
Kang Zhang, Yun Han, Zaiwei Wang, Yabo Zhao, Ya-li Fu, Xiuli Peng   +5 more
semanticscholar   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

Isolated Toll-like receptor transmembrane domains are capable of oligomerization. [PDF]

PLoS ONE, 2012
Toll-like receptors (TLRs) act as the first line of defense against bacterial and viral pathogens by initiating critical defense signals upon dimer activation.
James I Godfroy, Mohammad Roostan, Yurii S Moroz, Ivan V Korendovych, Hang Yin   +4 more
doaj   +1 more source

Polymorphisms of inflammation-related genes and susceptibility to childhood leukemia: evidence from a meta-analysis of 16 published studies

Hematology, 2023
Objective: This study was to comprehensively clarify the associations between single nucleotide polymorphisms (SNPs) in inflammatory genes and the susceptibility to childhood leukemia.Methods: Eligible articles were collected from the databases of PubMed,
Qiuping Zeng, Haoyan Ren, Cui Liu, Ting Liu, Yongwu Xie, Xiufu Tang   +5 more
doaj   +1 more source

Ligand‐specific tuning of CLEC10A signalling strength and dendritic cell responses through engagement of different GalNAc‐containing glycan structures

The FEBS Journal, EarlyView.
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs, Remi Hatinguais, Mike de Kok, R. J. Eveline Li, Tesfay M. Godefa, Victor L. J. L. Thijssen, Yvette van Kooyk, Sandra J. van Vliet   +7 more
wiley   +1 more source

АССОЦИАЦИЯ ПОЛИМОРФИЗМОВ ГЕНОВ TLR2, TLR4 И TLR6 С КОЛОНИЗАЦИЕЙ STREPTOCOCCUS PNEUMONIAE У РАБОТНИКОВ МЕТАЛЛУРГИЧЕСКОГО ПРОИЗВОДСТВА

Медицина в Кузбассе
Работники предприятий черной металлургии подвергаются воздействию промышленных аэрозолей органической и неорганической природы, что может приводить к нарушению механизмов врожденного иммунитета и увеличению частоты респираторных инфекций.
Татьяна Викторовна Бушуева, Елизавета Павловна Артёменко, Наталья Алексеевна Рослая, Юлия Витальевна Грибова, Алла Константиновна Лабзова, Владимир Борисович Гурвич   +5 more
doaj   +1 more source

Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus

Frontiers in Immunology, 2023
Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine inflammatory response at insemination, but its precise mechanism at molecular-level remains unknown.
Alireza Mansouri, Mohamed Samy Yousef, Mohamed Samy Yousef, Rasoul Kowsar, Nonoka Usui, Ihshan Akthar, Akio Miyamoto   +6 more
doaj   +1 more source

Toll-like receptor (TLR) 2 and TLR4 gene expression in canine heart [PDF]

, 2007
Toll-like receptors (TLRs) are archetypal pattern recognition receptors of immediate importance for an efficacious innate immune response. TLRs exhibit marked differential tissue activity and their levels within a discrete cell type can be highly dynamic.
Blecha, Frank, Linde, Annika, Melgarejo, Tonatiuh   +2 more
core   +2 more sources

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source