Results 51 to 60 of about 18,028 (232)

Toll-Like Receptor (TLR) 1, 2, and 6 Gene Polymorphisms Support Evidence of Innate Immune Factors in Schizophrenia

open access: yesNeuropsychiatric Disease and Treatment, 2023
Carlo E Sotelo-Ramírez,1,2 Beatriz Camarena,2 Marco Antonio Sanabrais-Jiménez,2 Julio Uriel Zaragoza-Hoyos,2 Bruno Ordoñez-Martínez,2 Raul I Escamilla-Orozco,3 Beatriz Gómez-González4 1Posgrado en Biología Experimental, Universidad Autónoma Metropolitana-
Sotelo-Ramírez CE   +6 more
doaj  

The Toll-Like Receptor 2 Ligand Pam2CSK4 Activates Platelet Nuclear Factor-κB and Bruton’s Tyrosine Kinase Signaling to Promote Platelet-Endothelial Cell Interactions

open access: yesFrontiers in Immunology, 2021
Circulating platelets establish a variety of immunological programs and orchestrate inflammatory responses at the endothelium. Platelets express the innate immunity family of Toll-like receptors (TLRs).
Iván Parra-Izquierdo   +12 more
doaj   +1 more source

Molecular evolution of the vertebrate TLR1 gene family - a complex history of gene duplication, gene conversion, positive selection and co-evolution [PDF]

open access: yes, 2011
Background: The Toll-like receptors represent a large superfamily of type I transmembrane glycoproteins, some common to a wide range of species and others are more restricted in their distribution.
Yinhua Huang   +5 more
core   +2 more sources

Association of TLR2 and TLR6 gene polymorphism with Trichomoniasis vaginalis Infection

open access: yesAdvancements in Life Sciences, 2023
Background: Toll-like receptors (TLR2 and TLR6) are a group of receptors that play a crucial role in the innate immune response and recognition of T. vaginalis. Single nucleotide polymorphisms (SNPs) in TLRs were manifested as important determinant affecting the susceptibility to trichomoniasis. This study aims to examine the impact of rs5743708 SNP in
Zainab Waddah Kermasha   +2 more
openaire   +1 more source

Synergic activation of toll-like receptor (TLR) 2/6 and 9 in response to Ureaplasma parvum & urealyticum in human amniotic epithelial cells. [PDF]

open access: yesPLoS ONE, 2013
Ureaplasma species are the most frequently isolated microorganisms inside the amniotic cavity and have been associated with spontaneous abortion, chorioamnionitis, premature rupture of the membranes (PROM), preterm labour (PL) pneumonia in neonates and ...
Martha Triantafilou   +5 more
doaj   +1 more source

Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population [PDF]

open access: yes, 2013
Background: The control of Mycobacterium tuberculosis (Mtb) infection begins with the recognition of mycobacterial structural components by toll like receptors (TLRs) and other pattern recognition receptors.
Angeles, Javier   +16 more
core   +1 more source

Whole genome sequencing of an African American family highlights toll like receptor 6 variants in Kawasaki disease susceptibility.

open access: yesPLoS ONE, 2017
Kawasaki disease (KD) is the most common acquired pediatric heart disease. We analyzed Whole Genome Sequences (WGS) from a 6-member African American family in which KD affected two of four children.
Jihoon Kim   +14 more
doaj   +1 more source

Contribution of toll-like receptor 2 and nicotinamide adenine dinucleotide phosphate oxidase to the trimethylamine N-oxide-induced inflammatory reactions in U937-derived macrophages [PDF]

open access: yesARYA Atherosclerosis, 2021
BACKGROUND: Trimethylamine N-oxide (TMAO) is emerging as a new generation of metabolites related to the activation of inflammatory reactions in the macrophages during atherosclerosis.
Abbas Ahmadi   +4 more
doaj   +1 more source

Signatures of positive selection in Toll-like receptor (TLR) genes in mammals [PDF]

open access: yes, 2011
International audienceUNLABELLED: ABSTRACT: BACKGROUND: Toll-like receptors (TLRs) are a major class of pattern recognition receptors (PRRs) expressed in the cell surface or membrane compartments of immune and non-immune cells.
Helena Areal   +2 more
core   +6 more sources

Association between Toll-Like Receptor Gene Cluster (TLR6, TLR1, and TLR10) and Prostate Cancer [PDF]

open access: yesCancer Epidemiology, Biomarkers & Prevention, 2007
Abstract Background: Chronic inflammation may be a risk factor for prostate cancer. Previously, we found significant associations between single nucleotide polymorphisms (SNPs) and haplotypes in Toll-like receptor (TLR) 4 and the risk of prostate cancer.
Chen, Yen-Ching   +4 more
openaire   +3 more sources

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