Results 51 to 60 of about 9,070 (169)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Determination of Genetic Variations of Toll-Like Receptor (TLR) 2, 4, and 6 with Next-Generation Sequencing in Native Cattle Breeds of Anatolia and Holstein Friesian

Diversity, 2016
In recent years, the focus of disease resistance and susceptibility studies in cattle have been on determining patterns in the innate immune response of key proteins, such as Toll-like receptors (TLR).
Nuket Bilgen, Bengi Cinar Kul, Victoria Offord, Dirk Werling, Okan Ertugrul   +4 more
doaj   +1 more source

Haplotype Disequilibrium in the TLR Genes of Czech Red Pied Cattle

Diversity, 2023
Hybrid resequencing of the antibacterial innate immune genes coding for toll-like receptors, namely TLR1, TLR2, TLR4, TLR5, and TLR6, using HiSeq and PacBio technologies of pooled population samples of Czech Simmental (Czech Red) cattle allowed us to ...
Kalifa Samaké, Karel Novák
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Association of Toll-like receptor polymorphism and gene expression level with the risk of developing chronic obstructive pulmonary disease (COPD) and its severity

Бюллетень сибирской медицины
Aim. Determine the influence of genetic factors of innate immunity on the risk of development and severity of COPD. Materials and methods. The study included 103 patients diagnosed with chronic obstructive pulmonary disease and 47 conditionally healthy ...
S. A. Salamaikina, V. I. Korchagin, K. O. Mironov, M. A. Karnaushkina   +3 more
doaj   +1 more source

TLRs and Bcl-2 family proteins in neutrophils of oral cavity cancer patients.

Folia Histochemica et Cytobiologica, 2010
Human neutrophils (PMNs), the cells engaged in the early phase of anti-tumor response, express TLR2 and TLR6 that can modulate the Bcl-2 family proteins, regulating the intrinsic apoptotic pathway in these cells.
Marzena Garley, Ewa Jablonska
doaj   +1 more source

Lung Pericytes: Molecular Mechanisms, Signaling Pathways, and Roles in Pulmonary Diseases

Comprehensive Physiology, Volume 16, Issue 4, August 2026.
Central role of pericytes across major pulmonary diseases. Conceptual wheel diagram illustrating the central role of lung pericytes across diverse pulmonary disease states. A pericyte positioned at the center expresses canonical markers, including PDGFRβ, CD146, and NG2, and connects radially to five major disease contexts.
Stuti Agarwal, Anuradha Bankar, Vinicio A. de Jesus Perez   +2 more
wiley   +1 more source

Additional file 1 of A 192 bp ERV fragment insertion in the first intron of porcine TLR6 may act as an enhancer associated with the increased expressions of TLR6 and TLR1

, 2021
Additional file 1: Table S1. Predicted Structural variations (SVs) of pig TLRs. Table S2 Number and origin of pig breeds for TLRs RIPs detection. Table S3 The primers for PCR, vectors construction and q-PCR.
Wang, XiaoYan, Chen, Zixuan, Murani, Eduard, D’Alessandro, Enrico, An, Yalong, Chen, Cai, Li, Kui, Galeano, Grazia, Wimmers, Klaus, Song, Chengyi   +9 more
openaire   +1 more source

Role for MyD88, TLR2 and TLR9 but Not TLR1, TLR4 or TLR6 in Experimental Autoimmune Encephalomyelitis [PDF]

The Journal of Immunology, 2011
Abstract The potential roles of TLRs in the cause and pathogenesis of autoimmune CNS inflammation remain contentious. In this study, we examined the effects of targeted deletions of TLR1, TLR2, TLR4, TLR6, TLR9, and MyD88 on the induction of myelin oligodendrocyte glycoprotein 35–55 (MOG35–55) peptide/CFA/pertussis toxin-induced ...
Miranda-Hernandez, Socorro, Gerlach, Nicole, Fletcher, Julie M., Biros, Erik, Mack, Matthias, Körner, Heinrich, Baxter, Alan G.   +6 more
openaire   +2 more sources